Peptides
GEP44: Inside the GLP-1/PYY Chimeric Peptide Research Model
GEP44 fuses GLP-1R and Y1/Y2 receptor pharmacophores into one peptide; explore chimeric design logic and rodent and shrew model findings.
Read articleEvidence-led explainers and analytical insights for serious research teams.
GEP44 fuses GLP-1R and Y1/Y2 receptor pharmacophores into one peptide; explore chimeric design logic and rodent and shrew model findings.
Read the articleGEP44 fuses GLP-1R and Y1/Y2 receptor pharmacophores into one peptide; explore chimeric design logic and rodent and shrew model findings.
Read articleBRP, a 12-amino-acid hypothalamic peptide found via peptidomic mining, alters feeding in rodent and porcine models independent of GLP-1R.
Read articleHow computational design balances GLP-1R, GIPR, and GCGR potency ratios in next-gen triple agonist candidates like ASC37.
Read articleExploring cone snail venom peptide libraries, disulfide frameworks, and alpha, omega, and mu conotoxin classes as channel-selective research probes.
Read articleResearch overview of metal-coordinating self-assembling peptides, mtDNA-driven cGAS-STING activation, and multivalent polymer-peptide mimics.
Read articleExamining phage-derived bicyclic peptides, RGD motif variants like norArg-Gly-Asp, and αvβ3 vs αIIbβ3 selectivity in conjugate research design.
Read articleFocused educational resources should make the next step obvious. Move from a research question into the corresponding Loti collection without losing context.
Start with focused, readable science written for research context.
Understand the methods, terminology, and variables that shape research.
Move directly into the relevant Loti research collection without dead ends.
Peptides
Peptides
Peptides