Loti Labs, based in the USA, stocks only domestically produced hexarelin for research. We know that only the highest quality products can lead to reliable answers, and we’ve invested in the infrastructure to guarantee that our peptides meet those standards. Importantly, hexarelin:like all peptides:must be handled by trained personnel in controlled settings.
Hexarelin Identity
What are Growth Hormone Releasing Peptides?
Hexarelin, also called examorelin, is a synthetic GHRP-6 analogue in which D-tryptophan is replaced by its 2-methyl derivative (Ong et al., 1998). Its sequence is His-D-Trp(2-Me)-Ala-Trp-D-Phe-Lys-NH2.
Hexarelin in Research on Ghrelin Function
Hexarelin is a useful research tool for studying ghrelin, a 28-amino-acid peptide that needs added lipid modification, called acylation, to attach to the GHS-R1a receptor.
Research on hexarelin and similar peptides is expanding consistently, particularly in clinical endocrinology.
Structure of Hexarelin (Growth Hormone-Releasing Peptide)
Bodart et al. (2002) identified CD36 as a hexarelin-binding protein in rat cardiac membranes. In perfused-heart experiments, hexarelin activation of CD36 was associated with increased coronary perfusion pressure. CD36 binding alone does not establish cardioprotection.
Cardiac CD36 Findings
Hormonal Interactions
Experimental Context
Mechanism of Action
These findings set a helpful foundation for the ongoing investigation of hexarelin.
When scientists study hexarelin to understand how it affects the heart and circulation, they should routinely check markers that show how the heart is working. Keeping an eye on heart function and related measurements helps ensure that the study is conducted properly and that the findings are meaningful.
Comparison to Other Peptides
Hexarelin, GHRP-2 and GHRP-6 belong to the growth hormone secretagogue class.
Scientists often use hexarelin in studies to see how it influences different body systems.
Conclusion
Hexarelin is a synthetic hexapeptide in the growth-hormone-releasing peptide family.
Chromatographic Purity and Compound Content
HPLC separates sample components and can be used to assess chromatographic purity. Determining absolute compound content requires a validated quantitative assay.
Customer reviews can tell you a lot, so read them and compare quality across different brands.
Mass Spectrometry and Identity
Mass spectrometry provides evidence supporting compound identity, where reported.
Hexarelin Sample Information
You can get Hexarelin straight from Loti Labs. Always pick USA-made peptides to keep your research on the right track. Loti Labs tests Hexarelin using HPLC and mass spectrometry for quality assurance. Each vial contains 2 mg of lyophilized powder, ready for your needs.
Arvat E, Ramunni J, Giordano R, et al. Hexarelin, a synthetic growth-hormone releasing peptide, does not affect corticotropin-releasing hormone or vasopressin on adrenocorticotropin or cortisol release in humans. Neuroendocrinology. 1997;66(6):393-400.
Bülow B, Møller N, Jørgensen JO. Eur J Endocrinol. 2012;167(4):413-427.
Ghigo E, Arvat E, Ramunni J, et al. J Clin Endocrinol Metab. 1997;82(8):2439-44.
Rahim A, O’Neill PA, Shalet SM. J Clin Endocrinol Metab. 1998;83(5):1644-1649.
Zhang J, Li L, Yang F, et al. Peptides. 2014;60:1-8.
Di Vito L, Arvat E, Ghigo E. J Endocrinol Invest. 2003;26(3):190-196.
Particle Peptides. Hexarelin. Available at: https://particlepeptides.com/en/content/16-hexarelin. Accessed June 2024.
Amazing Meds. What is Hexarelin? Available at: https://amazing-meds.com/what-is-hexarelin. Accessed June 2024.
Loti Labs. An In-depth review of Hexarelin - A Next Generation GHRP. Available at: https://lotilabs.com/resources/hexarelin-review/. Accessed June 2024.
This educational material discusses laboratory research concepts only. Loti Labs products are intended strictly for research and development use and are not for human consumption.
