Epitalon peptide is a synthetic compound that research shows may interact with telomerase activity in the lab. Studies suggest this substance may affect telomere characteristics in cell models. Research findings show Epitalon may also impact melatonin related pathways and circadian rhythm markers in experimental conditions. Learn more about these research observations and the science behind Epitalon in this research summary.
Key Research Findings
- Epitalon, a synthetic tetrapeptide developed for research purposes, shows activity in the lab to activate telomerase activity which research suggests leads to changes in telomere characteristics in cell models.
- In these lab studies differences between groups are considered statistically significant when P ≤ 0.05, meaning Epitalon has a real effect on cellular parameters. Lab studies show Epitalon increases certain cellular parameters in skin cell cultures, elasticity markers, moisture retention and textural characteristics and interacts with hormonal pathways through melatonin related mechanisms in experimental conditions.
- Research suggests Epitalon’s antioxidant properties and ability to modulate cellular behavior makes it a hot topic in aging research and cellular biology and has implications for regenerative research.
Epitalon Peptide: Research Applications in Cell Studies and Lab Investigation
Epitalon, a synthetic tetrapeptide, is being researched for its applications in cell studies and lab investigations. Developed by Russian scientist Vladimir Khavinson in the late 20th century Epitalon is made of 4 amino acids: alanine, glutamic acid, aspartic acid and glycine including the important amino acid glycine. Epitalon is also known as the AEDG peptide and research has looked at its molecular interactions with histones, its effect on gene and protein expression related to neurogenesis and cellular aging and its epigenetic mechanisms in the lab. Research also shows Epitalon may influence regulatory factors involved in gene expression and cellular function in lab models.
This pineal gland derived peptide compound is designed to research telomerase activity, an enzyme that lab studies show can affect telomere characteristics in experimental conditions. Research shows Epitalon may modulate cellular processes at the tissue level in lab models, telomere maintenance, cellular senescence markers and tissue specific aging indicators in research applications.Lab studies show Epitalon may have many research applications especially in cellular biology. Research shows this compound increases certain parameters in skin cell cultures by improving elasticity markers, moisture characteristics and overall textural properties in experimental conditions. Lab studies also show Epitalon stimulates collagen production in cell models which research shows can further increase elasticity markers and appearance related characteristics in experimental conditions. These research findings make Epitalon a hot topic in cellular biology and longevity research applications.
Beyond its cellular research applications Epitalon seems to interact with hormonal pathways by modulating melatonin production mechanisms in pineal gland research models. Melatonin is a key player in regulating sleep cycle markers and overall circadian rhythm characteristics in experimental conditions which research shows are essential for optimal cellular function in lab settings. Research shows Epitalon increases melatonin synthesis pathways which contributes to better sleep pattern markers and overall cellular well being indicators in research applications.
The peptide’s research potential goes beyond cellular studies and hormonal pathway research. Lab studies show Epitalon may be involved in cellular aging research by increasing telomere length characteristics in experimental models allowing cellular samples to divide more without reaching their theoretical division limit. This ability to support cellular longevity markers makes Epitalon a candidate in regenerative research.
As the quest for cellular optimization and longevity research continues Epitalon is a natural peptide with many research potential. Wholesale Peptide is committed to providing high quality, USA made Epitalon for research purposes so scientists and researchers can have the best tools for their lab investigations.
Introduction
Almost half of the research institutions are increasing their focus on cellular studies in the last few years and the interest in aging research and peptide research has surged. As researchers dig deeper into cellular biology peptide compounds help overcome challenges in cellular health research and longevity research. These natural compounds have many research applications that make them valuable in lab settings.
Epitalon peptide research is getting attention for its potential in supporting cellular studies and regenerative research applications. While peptide compounds don’t reverse cellular damage in experimental conditions lab studies show they may slow down certain cellular aging markers and improve elasticity characteristics in research models which contributes to cellular function and experimental appearance markers. This makes them a hot topic in aging and longevity research applications.Wholesale Peptide is a supplier of research grade peptides and committed to providing high quality compounds for research. We focus on USA made peptides and follow strict peptide regulations and guidelines so researchers can have reliable tools for their lab investigations.
As you read on you will learn about the research potential of Epitalon and its role in cellular biology and lab optimization studies.
What is Epitalon Peptide and Its Connection to the Pineal Gland
Epitalon is a synthetic tetrapeptide. It is composed of alanine, glutamic acid, aspartic acid and glycine and is a synthetic tetrapeptide for research purposes. Developed by the famous Russian scientist Vladimir Khavinson (Khavinson V) in the late 20th century Epitalon was created to study its effects on cellular aging markers and overall cellular function in lab settings. As a pineal gland derived peptide Epitalon has many research applications especially in aging and longevity research.
Lab studies show Epitalon can increase telomere length characteristics in cellular samples allowing experimental cells to divide more without reaching their theoretical division limit. Telomeres are protective caps on the ends of chromosomes that shorten as cells divide in lab conditions and contribute to cellular aging markers. Research shows Epitalon may delay certain cellular aging processes and support overall cellular function indicators by modulating telomere characteristics in experimental conditions.
Besides its effects on telomere markers lab studies show Epitalon has shown promise in cellular rejuvenation characteristics in research applications. Research shows Epitalon can improve elasticity markers, moisture characteristics and overall textural properties in experimental conditions which contributes to appearance indicators in lab models. This makes it a hot topic in cellular research and aging related studies.Research shows Epitalon also modulates hormonal pathway markers especially in melatonin production mechanisms in experimental conditions. Melatonin is a hormone that regulates sleep cycle markers and overall circadian rhythm in lab conditions. By increasing melatonin synthesis pathways in research models lab studies show Epitalon may support sleep pattern markers and overall cellular well being indicators. Research has also explored how Epitalon influences protein synthesis mechanisms as part of its role in cellular rejuvenation studies especially through gene expression and chromatin structure in experimental conditions. These multiple research applications make Epitalon a hot topic in peptide bioregulators research.
Mechanism of Action: How Epitalon Works in Lab Settings
Lab studies show Epitalon activates telomerase activity, an enzyme that restores telomere length characteristics and improves cellular function markers and longevity indicators in experimental conditions. Telomerase maintains the protective caps on the ends of chromosomes, the telomeres, which shorten with each cell division in lab settings. Research shows that increasing telomerase activity, epithalon peptide studies suggest telomerase activation may allow cellular samples to divide more and influence aging processes and cellular function markers in research applications.
Lab studies show Epitalon can increase the expression of genes related to oxidative stress and inflammation markers in experimental conditions. Epitalon interacts with cytoplasmic and nuclear components, can permeate cell membranes, localize to the nucleus and bind to DNA and histones and modulate gene expression and chromatin structure. This epigenetic mechanism suggests Epitalon may stimulate cellular detoxification and repair pathways in research models especially beneficial for aging tissue research. Studies have measured changes in mRNA expression to see how Epitalon affects gene activity, neurogenic differentiation markers and cellular proliferation in lab settings. These molecular mechanisms are key to understanding how Epitalon supports overall cellular function and longevity research.The mechanism also includes antioxidant effects that research shows may counteract some aging processes in experimental conditions. Lab studies show Epitalon can reduce oxidative stress markers and protect cellular samples from environmental damage indicators in research settings. Research shows Epitalon also modulates mitochondrial activity and mitochondrial membrane potential, both important for cellular energy markers and potentially aging processes in lab conditions. This ability to reduce oxidative damage markers makes Epitalon a hot topic in aging and longevity research.
Besides its antioxidant properties lab studies show Epitalon influences melatonin synthesis pathways and immune response markers in experimental conditions. Melatonin is essential for sleep cycle markers and circadian rhythm markers which research shows are important for optimal cellular function in lab conditions. Research shows Epitalon may increase melatonin production mechanisms, support sleep pattern markers and overall cellular well being indicators in experimental applications. These mechanisms make Epitalon a research topic in peptide studies and regenerative research.
Epitalon Research Findings
Research on Epitalon has shown some interesting results. Lab studies show Epitalon research may increase cellular functions and longevity markers in animal models. In vivo studies have been done to see Epitalon’s biological effects including aging related, neuroprotective and immunomodulatory activities in living organisms. For example research shows Epitalon can extend lifespan in fruit flies and telomere length in mice models. Studies have also been done on spontaneous tumor formation in animal models treated with Epitalon, showing its effect on formation or suppression of naturally occurring tumor markers in experimental conditions. Notably research has looked at spontaneous tumor incidence and showed Epitalon can reduce natural occurrence of tumors in animal models and may have a role in cancer prevention research. These findings make Epitalon a research topic in aging and longevity.In lab studies Epitalon has shown significant improvements in health metrics of older subjects, including mortality rate indicators. These results show Epitalon’s potential to support overall cellular function and longevity in experimental conditions. But please note that the products sold by Wholesale Peptide are for research purposes only and not for any other applications. Epitalon should be used within proper laboratory protocols.
The following sections will go into more detail on telomere elongation studies, antioxidant property research and effects on circadian rhythm and sleep markers in experimental conditions. These will show the many applications of Epitalon in research.
Telomere Elongation, Telomerase Activity, Cellular Aging
Telomeres, the caps on the end of chromosomes, are important in cellular aging research. As cells divide in lab conditions telomeres shorten and eventually cells enter senescence and aging markers in experimental conditions. Research shows Epitalon may influence telomere length and potentially some aging processes and cellular function markers in lab applications. Researchers measure relative telomere length to see the effect of Epitalon on cellular aging in lab models. This ability to support telomere elongation research is a major focus of aging and longevity research.
In animal studies Epitalon has shown promising results in telomere length and cellular function markers in experimental conditions. Lab findings show Epitalon may allow treated cells to divide more without reaching their theoretical division limit, contributing to cellular function and longevity markers in research applications. These results show Epitalon’s potential in overcoming age related cellular processes in lab research.
Moreover lab studies have shown significant improvements in health metrics of older subjects after Epitalon treatment, including mortality rate indicators. These results show Epitalon’s potential to support overall cellular function and longevity, making it a research topic in aging and longevity research and age related research.
Antioxidant Properties in LabOxidative stress is a major factor in aging research, causing cellular damage and dysfunction markers, including accumulation of intracellular reactive oxygen species in experimental conditions. Research shows Epitalon may have antioxidant properties that can reduce oxidative stress markers and reduced oxidative stress indicators, protect cellular samples from environmental damage in lab settings. This ability to reduce oxidative damage markers makes Epitalon a research topic in aging and longevity research.
Lab studies show Epitalon can reduce lipid peroxidation level markers which are indicators of oxidative stress in experimental conditions. By reducing lipid peroxidation Epitalon may protect cellular samples from oxidative damage and support overall cellular function in lab applications. This antioxidant effect is particularly useful for aging tissue research which is more prone to oxidative stress in lab settings.
Moreover lab findings show Epitalon has better antioxidant properties than Epithalamin, another peptide with similar properties in research applications. This enhanced antioxidant capability makes Epitalon a major research topic to understand its role in reducing oxidative stress markers and supporting cellular function in lab research.
Effects on Circadian Rhythm and Sleep Markers in Research
Circadian rhythm and sleep pattern markers are important for overall cellular function and well being in lab conditions. Research shows Epitalon may increase melatonin production mechanisms which are important for circadian rhythm in experimental conditions. By stimulating the pineal gland in research models Epitalon may support sleep pattern markers and overall cellular function indicators, regulating circadian rhythm in experimental applications.
Lab studies show Epitalon can restore melatonin production in aged research subjects, improve sleep quality in experimental conditions. Some studies have also looked into Epitalon’s potential to support cognitive function as part of its overall impact on cellular wellness. This ability to increase melatonin synthesis pathways makes Epitalon a research topic in sleep and circadian rhythm research. Improved sleep quality is important for optimal cellular function and well being, especially in aging population research applications.Also research shows Epitalon can normalize circadian rhythm which degrades with aging in lab models. Lab findings show Epitalon can support sleep pattern markers and regulate circadian rhythm, contribute to overall cellular optimization in experimental conditions. These findings highlight the many applications of Epitalon in sleep and circadian rhythm research.
Epitalon Research
Epitalon, a synthetic tetrapeptide composed of 4 amino acids—alanine, glutamic acid, aspartic acid, and glycine—has many research applications in aging and longevity research. One of its main research actions is to stimulate gene expression related to telomerase activity which leads to telomere elongation in lab conditions. This is important in aging research as longer telomeres allow cellular samples to maintain their division potential and overall vitality in experimental conditions. Epitalon research is relevant to biological aging and interventions to slow down age related decline.
By reducing oxidative stress markers and intracellular reactive oxygen species in research applications, lab studies show Epitalon supports cellular function and may contribute to cellular protection research. Its antioxidant properties protect cellular samples from environmental damage characteristics, further supporting longevity research and cellular aging research. Moreover research shows Epitalon’s influence on pineal gland increases melatonin production mechanisms which are important for circadian rhythm and sleep markers—both important in overall cellular well being research applications.
The peptide’s ability to modulate oxidative stress markers benefits cellular function research and also maintains cellular characteristics in lab studies. By supporting the body’s natural defense mechanisms against free radical activity in experimental conditions, research shows Epitalon may reduce some aging markers such as cellular damage and elasticity loss in lab applications. These combined effects make Epitalon a good candidate for those interested in longevity research and optimal cellular function research.
Lab Research
Epitalon has many applications in lab research making it a useful tool for scientists and researchers. It has been studied in cell culture and cellular culture systems with various cell types such as stem cells, neuroblastoma cells, fibroblasts, HeLa cells to see its effect on cellular processes, aging markers and differentiation characteristics in research conditions. Epitalon has been studied on its ability to penetrate cellular membrane structures and influence intracellular processes, its direct cellular activity in lab conditions. Epitalon can interact with the cell membrane to facilitate its entry into cells and modulate intracellular pathways and epigenetic mechanisms. Confocal laser scanning microscopy has been used to visualize the localization and structural effects of Epitalon on cells and tissues in experimental applications. Also research has analyzed the expression of neuronal markers such as β tubulin iii to see Epitalon’s role in neuronal differentiation in lab studies. Lab findings show that Epitalon can activate signaling pathways related to cell growth and inflammatory response markers which are important in understanding cellular behavior in research applications. This ability to modulate cell signaling makes Epitalon a key research topic in cellular biology and inflammation research.
Research shows co-exposure with Epitalon and pro-inflammatory inducers can lead to complex signaling events and influence cellular behavior and gene expression characteristics in lab conditions. This ability to modulate gene expression makes Epitalon a good subject for studies in inflammation and cellular function research applications. Also lab studies show Epitalon can downregulate cytokine release in macrophage research models, it can modulate inflammatory response markers in experimental conditions.
Phosphorylation of transcription factors like STAT1 indicates Epitalon’s role in regulating gene expression related to inflammation markers in research applications. This ability to modulate gene expression and cellular behavior stimulates gene expression characteristics, making Epitalon a useful tool for research in gene expression analysis and cell signaling research. Moreover lab studies show increased phosphorylation of kinases like ERK1/2 by Epitalon is important for mitogenic signaling in cellular research applications.Epitalon peptide research applications are in protein research, cell signaling research and gene expression analysis research. Epitalon peptide gives insights into cellular behavior and inflammatory response markers and contributes to understanding of cellular processes and function research applications. Wholesale Peptide provides high quality Epitalon for research purposes so that scientists have the best tools for their laboratory research.
Epitalon Peptide: Research Applications Beyond Basic Lab Research
While Epitalon’s lab applications are well documented, its research potential goes beyond lab research. In cellular samples and stem cell research models, lab findings show Epitalon can stimulate neuronal differentiation gene expression especially in gingival mesenchymal stem cell research applications. This suggests a possible research role for Epitalon in neuroregenerative research where promoting new neuronal characteristics can help in studying neurodegenerative conditions in lab settings.
Epitalon’s research impact is not limited to nervous system research. Lab studies show the peptide can enhance immune system function markers by influencing the thymus, an organ important for immune function research in experimental conditions. Research has also shown Epitalon can support immune function in experimental models, it can boost immune responses and tumor suppression. This can contribute to longevity research by supporting the body’s natural defense mechanisms against age related cellular processes in lab applications. Also research findings show Epitalon has shown characteristics in reproductive research, improving oocyte maturation markers and reducing oocyte fragmentation indicators—important for fertility research and cellular aging research.
The peptide’s antioxidant properties and ability to modulate mitochondrial activity further expands its research applications. By supporting mitochondrial function markers in lab conditions, research shows Epitalon can help address conditions associated with mitochondrial dysfunction characteristics which are often linked to aging process research. These diverse effects make Epitalon a tool in regenerative research and can improve cellular quality markers as research subjects age in lab conditions.
Research Considerations and Lab Protocols
As with any peptide research compound, understanding the research considerations and potential lab observations of Epitalon exposure is important for proper experimental design. Current research shows Epitalon is generally well tolerated in lab settings with few reported adverse reactions in research applications. However as with all experimental compounds, careful monitoring and adherence to recommended lab protocols is crucial to minimize experimental variables.Epitalon effects may vary depending on the administration method in lab settings, whether by injection protocols or alternative delivery methods in research applications. Short term studies show good research characteristics but long term studies of Epitalon exposure in lab conditions are still needed. Clinical trials are required to establish the safety and efficacy of Epitalon in broader research applications. Also consider the possibility of interactions with other research compounds or experimental conditions that can affect the overall research outcome of peptide studies.
As more research emerges, the effects of Epitalon and its research profile will become clearer. Until then, Epitalon should be used only in research settings and any potential applications should be approached with proper lab protocols and under professional research supervision.
Quality Assurance at Loti Labs
At Loti Labs, quality assurance is our top priority for research applications. We follow Good Manufacturing Practices (GMP) and ensure high quality peptide production through multiple stages of quality control including purity testing for research compounds. This ensures researchers get reliable and consistent products for their lab research.
Advanced analytical techniques like High-Performance Liquid Chromatography (HPLC) are used to confirm the purity and potency of peptides for research applications. This rigorous testing process guarantees each batch of research compounds meets the highest standards of quality and reliability for lab use. Also every single batch is industry leading third party tested to ensure the peptides sold by Loti Labs for research purposes are reliable.
Transparency in our manufacturing process allows our customers to know the sourcing and production methods used for research peptides. A team of experts with years of experience in peptide synthesis, purification and analysis support Loti Labs’ commitment to quality research compounds. Researchers can trust they are getting the best products for their scientific exploration and lab research.
Why Choose USA-Made Peptides for Research Applications?
Choosing USA-made peptides has several advantages for research applications especially in terms of quality and regulatory compliance for lab use. USA-made peptides are high quality and follow strict regulations and guidelines, researchers get reliable and consistent products for their lab research. Adhering to strict standards minimizes the risk of contamination and ensures research integrity in experimental applications.Locally produced peptides have shorter supply chain, less risk of contamination and fresher products for research use. This is crucial for maintaining the effectiveness and reliability of peptides used in lab research. Loti Labs prides itself on providing high quality, USA-made peptides for research applications.
In addition to quality and regulatory compliance, USA-made peptides often come with great customer service and bulk availability for research. Loti Labs is committed to fast and helpful customer service so researchers have the support they need for their lab research. Researchers choosing Loti Labs can trust the quality and reliability of their peptide products for research.
In summary, Epitalon peptide is a promising candidate in cellular aging and function optimization research. Its ability to affect telomere characteristics, be antioxidant and affect melatonin production mechanisms makes it a great subject for ongoing lab research. Recent studies have shown Epitalon’s good bioactivity, geroprotective effects and possible role in increasing lifespan and tissue health. Research suggests Epitalon can support cellular function markers, improve sleep pattern characteristics and contribute to overall longevity research, making it a hot topic in aging and longevity research.
Loti Labs provides high quality, USA-made Epitalon for research. With multiple stages of quality control including GMP and advanced analytical techniques, Loti Labs ensures researchers get reliable and consistent products for their lab research. By choosing Loti Labs, researchers can trust they are getting the best tools for their scientific exploration and experimental research.
As we continue to research Epitalon and other peptides, the future of aging research and cellular optimization looks promising. The advancements in peptide research and regenerative research will uncover new insights in cellular function and longevity research, and lab research methodologies.
Conclusion and Future Research Directions
Epitalon is at the forefront of aging and longevity research, offering a way to address cellular aging markers and age-related research. By influencing telomerase activity and supporting melatonin production in lab conditions, this peptide bioregulator can promote cellular aging research and potentially extend research in longevity. Its multiple effects on gene expression, antioxidant defense and cellular function make it a research compound in experimental applications.
Looking forward, future research should uncover the molecular mechanisms of Epitalon in lab conditions, explore its applications in regenerative research and conduct rigorous experimental protocols and research. Clinical research will be necessary to validate Epitalon’s effects, especially on telomeres, melatonin, immune function and lifespan extension and to expand its therapeutic applications. As we learn more through lab research, Epitalon might become a valuable tool in studying cellular aging and cellular quality research.
Epigenetic Mechanism and AEDG Peptide
AEDG peptide, also known as Epitalon, is a hot topic in epigenetic research and cellular health. Epigenetics is the study of heritable changes in gene expression that occur without changing the underlying DNA sequence and recent research has shown AEDG peptide can modulate these processes in human somatic cells.
At molecular level, AEDG peptide is composed of 4 amino acids—alanine, glutamic acid, aspartic acid and glycine—in a specific amino acid sequence that is essential for its biological activity. This sequence allows the peptide to interact with specific amino acid residues on target proteins and influence various cellular pathways. Research has shown that AEDG peptide can stimulate gene expression and support proliferation and differentiation in human cells which are crucial for tissue regeneration and overall cellular function.One of the most interesting aspects of AEDG peptide action is its effect on telomeres. Telomeres are repetitive DNA sequences at the end of chromosomes that protect genetic material during cell division. Over time telomeres naturally shorten and contribute to cellular senescence and aging. Research using taqman gene expression and other molecular techniques has shown that AEDG peptide can increase telomerase activity and elongate telomeres and improve cellular health in experimental models. This has been seen in human somatic cells and in vitro studies with bovine cumulus cells where the peptide increased cell viability and reduced chromosomal abnormalities.
The pineal gland, known for its role in melatonin synthesis and circadian rhythms, is another target of AEDG peptide. Laboratory research has shown that the peptide can modulate gene expression in the pineal gland and increase melatonin secretion. This regulation of melatonin synthesis not only supports circadian rhythm stability but also overall cellular health as melatonin is a potent antioxidant and regulator of cellular processes.
A possible epigenetic mechanism of AEDG peptide action is its interaction with histone proteins. Histones are the building blocks of chromatin and play a central role in controlling gene accessibility and expression. AEDG peptide has been shown to modulate histone modification and chromatin remodeling and change gene expression in human cells. This can lead to increased cellular resilience, improved differentiation and reduced oxidative stress.
In addition to its effect on gene expression and chromatin structure, AEDG peptide has antioxidant properties. Experimental data shows that the peptide can decrease ROS production and support mitochondrial function and protect cells from oxidative damage. This has been seen in studies with bovine cumulus cells where AEDG exposure reduced oxidative stress markers and improved cellular outcomes. In summary AEDG peptide’s epigenetic regulation, telomere maintenance and cellular health makes it a promising candidate in healthy aging and longevity research. While the exact mechanisms are still being explored, current data shows the peptide’s multifaceted role in optimal gene expression, reducing oxidative stress and supporting human cell function. Further research will be needed to fully understand the therapeutic potential and broader applications of AEDG peptide in age-related and regenerative research.
FAQs
How do Loti Labs guarantee the quality of peptides sold for research purposes?
Loti Labs guarantees the quality of peptides sold for research applications through industry leading third-party testing of every batch. This rigorous testing process ensures customers receive high quality products for their laboratory research.
For what use are the peptides sold by Loti Labs?
The peptides sold by Loti Labs are for laboratory research use only. Not for any other use beyond scientific research.
What are the applications of peptides according to Loti Labs guidelines?
Peptides have applications in research investigations, diagnostics and experimental studies, particularly in protein studies, cell signaling research and gene expression analysis research. Hence they are versatile tools across various scientific fields and laboratory applications.
Why should customers choose USA made peptides for research applications?
Customers should choose USA made peptides for their superior quality and compliance with strict regulations for research use, ensuring reliability and consistency in laboratory applications and experimental research.
What is emphasized in the manufacturing process of Loti Labs research products?
The manufacturing process of Loti Labs products emphasizes multiple stages of quality control, particularly purity testing for research applications. This ensures the final product meets high standards for quality and reliability in laboratory research.
References
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- Anisimov, V.N., et al. Effect of Epitalon on Biomarkers of Aging, Life Span and Spontaneous Tumor Incidence in Female Swiss-Derived SHR Mice. Biogerontology, 4, 193-202 (2003).3. Khavinson, V.K., et al. Peptide Bioregulators: The New Class of Geroprotectors. Advances in Gerontology, 26(1), 20-37 (2011).
- Fedoreyeva, L.I., et al. Penetration of Short Fluorescence-Labeled Peptides into the Nucleus in HeLa Cells and In Vitro Specific Interaction of the Peptides with Deoxyribooligonucleotides and DNA. Biochemistry Biokhimiia, 76(11), 1210-1219 (2011).
- Kozina, L.S., Arutjunyan, A.V., Khavinson, V.K. Antioxidant Properties of Geroprotective Peptides of the Pineal Gland. Archives of Gerontology and Geriatrics, 44(Suppl 1), 213-216 (2007).
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- Khavinson, V.K., et al. Epithalon Peptide Induces Telomerase Activity and Telomere Elongation in Human Somatic Cells. Bulletin of Experimental Biology and Medicine, 135(6), 590-592 (2003).
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- Kozina, L.S., et al. Antioxidant Properties of Geroprotective Peptides of the Pineal Gland. Archives of Gerontology and Geriatrics, 44(1), 213-216 (2007).
- Fedoreyeva, L.I., Kireev, I.I., Khavinson, V.K., Vanyushin, B.F. Penetration of Short Fluorescence-Labeled Peptides into the Nucleus in HeLa Cells and In Vitro Specific Interaction of the Peptides with Deoxyribooligonucleotides and DNA. Biochemistry Biokhimiia, 76(11), 1210-1219 (2011).20. Anisimov, V.N., et al. Epitalon Effects on Aging Markers, Lifespan and Spontaneous Tumor Incidence in Female SHR Mice. Biogerontology, 4(3), 193-202 (2003).
- Araj, S.K., et al. Epitalon—A Highly Bioactive Pineal Tetrapeptide with Multifunctional Properties. International Journal of Molecular Sciences, 26(6), 2691 (2025).
- Ullah, S., et al. Epitalon Induces Telomerase Activation in Bovine In Vitro Embryo Production. Journal of Molecular Sciences (2025).
- Gatta, M., Dovizio, M., Milillo, C., et al. Epitalon Enhances Delayed Wound Healing in an in Vitro Model of Diabetic Retinopathy. Stem Cell Reviews and Reports (2025).
- Khavinson, V.K., et al. Peptide Control of Cell Differentiation. Stem Cell Reviews and Reports, 16(1), 118-125 (2020).
- Khavinson, V.K., et al. Retina Pathology and Its Correction. Springer Nature, Berlin/Heidelberg (2020).
- Khavinson, V.K., et al. Peptide Bioregulators: New Geroprotectors. Advances in Gerontology, 25(4), 696-708 (2012).
- Khavinson, V.K., et al. Peptide Regulation of Gene Expression. Molecules, 26(22), 7053 (2021).
- Khavinson, V.K., et al. Epitalon Improves Eye Retina in Retinitis Pigmentosa. Neuroendocrinology Letters, 23(4), 365-368 (2002).
- Anisimov, V.N., et al. Epitalon Inhibits Colon Carcinogenesis Induced by 1,2-Dimethylhydrazine in Rats. Cancer Letters, 183(1), 1-8 (2002).30. Anisimov, V.N., et al. Epitalon on Aging Markers, Lifespan and Spontaneous Tumor Incidence in Female SHR Mice. Biogerontology, 4(3), 193-202 (2003).
- Khavinson, V.K., et al. Epithalon stimulates Telomerase and Telomere elongation in human somatic cells. Bulletin of Experimental Biology and Medicine, 135(6), 590-592 (2003).
- Ullah, S., et al. Epitalon induces Telomerase and improves bovine in vitro embryo production. Journal of Molecular Sciences (2025).
- Gatta, M., Dovizio, M., Milillo, C., et al. Epitalon enhances delayed wound healing in an in vitro model of diabetic retinopathy. Stem Cell Reviews and Reports (2025).
- Khavinson, V.K., et al. Peptide control of cell differentiation. Stem Cell Reviews and Reports, 16(1), 118-125 (2020).
- Khavinson, V.K., et al. Retina pathology and its correction. Springer Nature, Berlin/Heidelberg (2020).
- Khavinson, V.K., et al. Peptide bioregulators – new geroprotectors. Advances in Gerontology, 25(4), 696-708 (2012).
