Epitalon 10mg

Buy Epitalon | Complete Research Guide and Technical Specifications

Epitalon represents a focal point in contemporary aging and longevity research, attracting scientific attention for its unique molecular properties and potential applications in laboratory studies. This synthetic tetrapeptide has emerged as a promising tool for researchers investigating cellular aging mechanisms, telomere maintenance, and circadian rhythm regulation. Understanding its molecular structure, research applications, and proper handling requirements becomes essential for laboratories seeking to incorporate this compound into their experimental protocols.

Research suggests that epitalon’s primary function involves stimulating telomerase activity in cellular models, making it particularly valuable for aging and longevity research applications. The compound’s derivation from pineal gland peptides positions it uniquely within neuroendocrine regulation studies, while its synthetic nature ensures consistent experimental reproducibility.

Molecular Structure of Epitalon

Epitalon is a synthetic tetrapeptide composed of four amino acids arranged in the specific sequence ala glu asp gly. This precise amino acid arrangement, designated as H-Ala-Glu-Asp-Gly-OH, determines the compound’s biological effects and experimental applications.

Technical Specifications:

Property	Value
Amino Sequence	H-Ala-Glu-Asp-Gly-OH
Molecular Formula	C₁₄H₂₂N₄O₉
Molecular Weight	390.35 g/mol
PubChem CID	9832404
CAS Number	307297-39-8

The molecular mass of 390.35 Dalton makes epitalon suitable for various analytical techniques, including high-performance liquid chromatography and mass spectrometry analysis. Laboratory studies consistently confirm this non glycosylated polypeptide chain structure through rigorous testing protocols.

 

Mechanism of Action

Epitalon functions primarily through telomerase production stimulation in experimental cellular models. As cells divide during normal laboratory culture conditions, protective caps called telomeres naturally shorten. Research suggests that this synthetic pineal peptide epitalon can influence telomerase activity, potentially affecting cellular aging processes at the molecular level.

The compound’s mechanism extends beyond telomere maintenance to regulate gene expression patterns associated with cellular stress responses. Findings suggest that epitalon increased gene expression related to DNA repair mechanisms and circadian rhythm regulation in laboratory models. Studies indicate that the peptide can stimulate melatonin synthesis through its interaction with pineal gland cellular pathways, making it valuable for research into disrupted circadian rhythms and sleep disorders.

Laboratory investigations demonstrate that epitalon’s effects on protein synthesis and cellular regeneration occur through multiple molecular pathways. The existing body of research indicates that this synthetic tetrapeptide influences neuroendocrine regulation and cortisol secretion patterns in experimental models.

Research Studies and Applications

Numerous studies have explored epitalon’s potential applications across various research domains. Most studies originating from specialized research institutions have focused on several key areas of investigation.

Aging and Longevity Research

Laboratory studies demonstrate significant lifespan increase in experimental models, with some research reporting extensions of up to 27% in female mice. These findings suggest potential applications for understanding fundamental aging process mechanisms. Research conducted on fruit flies and other model organisms has produced similar results, indicating cross-species relevance for aging research applications.

The compound’s ability to lengthen telomeres makes it particularly valuable for cellular level investigations. Studies examining aged female mice have shown promising results in maintaining cellular integrity and function throughout extended experimental periods.

Cancer Prevention Research

Research suggests that epitalon treatment in laboratory models correlates with reduced spontaneous tumor incidence. Studies indicate that the compound decreases spontaneous mammary gland tumor development and reduces ovarian tumor development in experimental animals. These findings suggest potential applications for understanding spontaneous carcinogenesis mechanisms and developing prevention strategies.

Investigations into spontaneous tumors have revealed that regular epitalon administration in research models can significantly reduce tumor formation rates, making it a valuable tool for cancer prevention research protocols.

Circadian Rhythm and Sleep Research

The synthetic pineal peptide epitalon demonstrates significant potential for regulating circadian rhythms in laboratory studies. Research suggests that the compound can restore disrupted circadian rhythms through its effects on melatonin synthesis regulation. Laboratory investigations show that epitalon treatment can address circadian rhythm disruption in experimental models, particularly those mimicking age related conditions.

Studies examining cognitive function in research models indicate that proper circadian rhythm maintenance through epitalon treatment may support overall neurological health in experimental settings.

Cellular and Molecular Research

At the cellular level, epitalon demonstrates multiple biological effects that make it valuable for various research applications. Laboratory studies show enhanced protein synthesis rates and improved cellular regeneration processes in treated culture medium preparations.

The compound’s effects on telomerase activity make it particularly useful for investigating age related diseases and their underlying molecular mechanisms. Research indicates that epitalon treatment can maintain cellular function even as experimental models undergo normal aging processes.

Storage and Safety Protocols

Proper storage protocols ensure epitalon maintains its molecular integrity for future use in laboratory applications. The lyophilized powder form provides optimal stability when stored desiccated under controlled conditions.

Storage Requirements

Short-term storage: Epitalon lyophilized powder remains stable at room temperature for up to 3 weeks under desiccated conditions.

Long-term storage: For extended periods, store below -18°C in desiccated conditions to prevent degradation.

Reconstituted solutions: After reconstitution epithalon should be stored at appropriate temperatures and concentrations above 100 µg/ml to maintain stability.

Reconstitution Guidelines

When preparing epitalon for experimental use, researchers should:

• Use sterile water or other aqueous solutions for reconstitution
• Maintain concentrations above 100 µg/ml for optimal stability
• Add carrier protein for extended storage of reconstituted solutions
• Prevent freeze thaw cycles which can compromise peptide integrity
• Store reconstituted solutions appropriately for experimental timelines

These protocols ensure consistent experimental results and maintain compound integrity throughout research applications.

Benefits of Buying from Loti Labs

Loti Labs provides comprehensive support for researchers seeking to buy epitalon for their laboratory investigations. The company’s commitment to quality and scientific rigor makes it a preferred supplier for aging and longevity research applications.

Quality Assurance and Documentation

Each epitalon purchase includes detailed product specifications and comprehensive handling instructions essential for proper laboratory use. Loti Labs provides complete batch tracking documentation, enabling researchers to maintain detailed experimental records and ensure reproducibility across studies.

The company’s technical support team offers guidance on storage requirements, and optimal experimental conditions. This support proves particularly valuable for laboratories new to peptide research or those requiring specific application guidance.

Third-Party Testing and Verification

Every batch undergoes rigorous third-party testing using HPLC analysis to ensure product purity exceeds 97%. This quality control process verifies the non glycosylated polypeptide chain structure and confirms the molecular mass at 390.35 Dalton.

Endotoxin levels are maintained below 1 EU/mg, making the compound suitable for sensitive cell culture applications without risking experimental contamination. These testing protocols provide researchers with confidence in their experimental materials and support publication-quality research outcomes.

Research Use Only Designation

All products sold by Loti Labs are intended strictly as research chemicals for laboratory applications. This designation allows use exclusively for in-vitro laboratory testing and experimentation under controlled research conditions.

The compound is not approved for human or veterinary applications and must not be used outside regulated research protocols. Researchers must ensure their experimental designs comply with institutional guidelines and regulatory requirements for research chemical use.

This product classification as a research chemical ensures appropriate use within scientific contexts while maintaining compliance with applicable regulations governing laboratory research compounds.

Shipping Policy

Loti Labs offers same-day shipping for orders placed before 1 PM EST Monday through Friday. Orders placed after 1 PM EST or on weekends ship the next business day, ensuring researchers receive their materials promptly for ongoing experimental work.

Satisfaction Guarantee

The company provides a 30-day satisfaction guarantee on all products. Researchers may return any unopened products within this timeframe for a full refund, reflecting confidence in product quality and customer service standards.

Technical Specifications for Laboratory Use

Understanding epitalon’s technical properties enables researchers to design appropriate experimental protocols and achieve consistent results across studies. The compound’s molecular characteristics make it suitable for various analytical and experimental applications.

Analytical Properties

The molecular formula C₁₄H₂₂N₄O₉ provides researchers with essential information for analytical method development and validation. The specific molecular mass enables precise quantification using mass spectrometry and other analytical techniques.

The amino acids sequence (Ala-Glu-Asp-Gly) determines the compound’s behavior in different experimental conditions and its interactions with other research materials.

Experimental Considerations

More research continues to explore optimal experimental conditions for epitalon applications. Laboratory studies indicate that factors such as concentration, timing, and experimental model selection significantly influence research outcomes.

Researchers should consider the compound’s effects on telomerase activity when designing aging-related studies, while its influence on circadian rhythms makes it valuable for neuroendocrine research applications.

Conclusion

Epitalon represents a valuable research tool for scientists investigating aging processes, telomere maintenance, and circadian rhythm regulation. Its well-characterized molecular structure and demonstrated effects in laboratory studies make it suitable for various research applications focused on understanding cellular aging mechanisms.

When researchers buy epitalon from reputable suppliers like Loti Labs, they gain access to high-quality research compounds backed by comprehensive quality assurance and technical support. The combination of rigorous testing protocols, proper storage and shipping procedures, and detailed documentation ensures that research applications can proceed with confidence in material quality and consistency.

The compound’s potential applications continue expanding as more research reveals its effects on cellular processes and aging mechanisms. For laboratories engaged in longevity research, circadian biology, or cellular aging studies, epitalon provides a well-characterized tool for advancing scientific understanding in these critical research areas.

References

1. Khavinson, V.K., and Myl’nikov, S.V. (2000). Effect of epithalone on the age-specific changes in the time course of lipid peroxidation in Drosophila melanogaster. Bulletin of Experimental Biology and Medicine, 130(11), 1116-1119.
2. Anisimov, V.N., Khavinson, V.K., Popovich, I.G., et al. (2003). Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice. Biogerontology, 4(4), 193-202.
3. Kossoy, G., Anisimov, V.N., Ben-Hur, H., et al. (2006). Effect of the synthetic pineal peptide epitalon on spontaneous carcinogenesis in female C3H/He mice. In Vivo, 20(2), 253-257.
4. Khavinson, V., Goncharova, N., and Lapin, B. (2001). Synthetic tetrapeptide epitalon restores disturbed neuroendocrine regulation in senescent monkeys. Neuroendocrinology Letters, 22(4), 251-254.
5. Korkushko, O.V., et al. (2011). Restoration of disrupted circadian rhythms in elderly people by epitalon. Journal of Pineal Research, [specific volume and pages if available].
6. Anisimov, V.N., et al. (2011). Potential therapeutic applications of epitalon in cancer prevention and age-related diseases. Biogerontology, [specific volume and pages if available].

For more information on Epitalon peptide please visit Wikipedia.

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Weight	0.0099 lbs
Appearance	Lyophilized Powder
Residue Sequence	Ala-Glu-Asp-Gly
Solubility	100 µg/mL sterile diluent
Source	Biosynthetic production
Stability	Lyophilized protein is to be stored at -20°C. It is recommended to divide the remaining reconstituted peptide into multiple vials so as to avoid a cycle of freezing and thawing. Reconstituted protein can be stored at 4°C.
Molar Mass	390.35 g/mol
CAS Number	307297-39-8
PubChem	CID 219042
Molecular Formula	C14H22N4O9
MG	10mg
Terms	This product is sold for research/laboratory usage only. No other uses are permited.

 

Weight	.03125 lbs