Letrozole 2.5mg/ml (30ml)

Buy Letrozole at Loti Labs: Premium Quality Research Compounds

Research into aromatase inhibitors continues to advance our understanding of hormonal pathways and their applications in various therapeutic contexts. Letrozole, a third-generation nonsteroidal aromatase inhibitor, has emerged as a critical compound for researchers studying hormone-dependent processes. For those seeking to buy letrozole for legitimate research purposes, understanding its molecular properties, mechanism of action, and sourcing requirements is essential for ensuring both quality and compliance.

Molecular Structure of Letrozole

Understanding the molecular foundation of letrozole provides crucial insights into its research applications and interaction mechanisms.

Chemical Name: 4,4’-(1H-1,2,4-triazol-1-ylmethylene)dibenzonitrile

Molecular Formula: C17H11N5

Molecular Weight: 285.3 g/mol

PubChem CID: 3902

CAS Number: 112809-51-5

The compound features two benzonitrile groups linked by a triazole moiety, which defines its specificity and binding interaction with the aromatase enzyme. This triazole-containing structure allows letrozole to selectively bind and inhibit aromatase, making it valuable for research into estrogen biosynthesis pathways. Researchers studying hormonal mechanisms find this precise molecular architecture essential for understanding how certain types of compounds interact with enzymatic processes in the body.

Mechanism of Action

Letrozole functions as a nonsteroidal aromatase inhibitor in research settings. The aromatase enzyme catalyzes the conversion of androgens, specifically androstenedione and testosterone, to estrogens. In postmenopausal women, estrogen synthesis occurs primarily in peripheral tissues such as adipose, muscle, and skin through this enzymatic pathway.

Research suggests that by inhibiting the aromatase enzyme, letrozole reduces circulating estrogen levels in experimental models. This mechanism proves particularly valuable in studies examining hormone-receptor-positive breast cancer, where estrogen acts as a growth factor for malignant cells. Laboratory research demonstrates that letrozole’s inhibition of estrogen synthesis can slow tumor growth that depends on estrogen stimulation.

Research Studies and Clinical Applications

Numerous large-scale randomized clinical trials have validated letrozole’s efficacy in research contexts. Studies indicate its effectiveness as adjuvant therapy following surgical interventions, extended adjuvant treatment after tamoxifen administration, and as first-line treatment for advanced hormone-dependent conditions.

Research Application	Standard Dose	Duration
Adjuvant Studies	2.5 mg daily	5 years
Extended Adjuvant	2.5 mg daily	Variable
Advanced Research	2.5 mg daily	Until progression

Research findings consistently demonstrate that letrozole maintains effectiveness across various experimental protocols. The most commonly studied and prescribed letrozole formulation involves 2.5 mg taken once daily. Treatment duration in research settings typically ranges from five years for adjuvant studies to indefinite periods for advanced research applications, depending on study parameters and progression markers.

Scientists note that letrozole exhibits linear pharmacokinetics with a half-life of approximately 2 days, supporting once-daily administration in research protocols. Peak plasma concentrations are typically achieved within 1-2 hours after administration, making it suitable for controlled research environments where precise timing matters.

Storage and Safety Considerations

Proper storage of letrozole ensures compound integrity and research validity. The substance should be stored at controlled room temperature, away from excessive moisture and heat. Strict adherence to storage guidelines preserves potency and efficacy throughout the research period.

Research indicates that letrozole’s effects profile relates primarily to estrogen depletion mechanisms. Common observations in research subjects include hot flashes, muscle pain, joint discomfort, and headache. Some studies report increased cholesterol levels and mild gastrointestinal responses in research populations.

More serious observations, though less common in research settings, include allergic reactions, thrombotic events, cardiovascular responses such as chest pain and hypertension, and hepatic changes. Researchers must note that letrozole carries significant risks and must not be used in pregnant subjects, nursing mothers, or premenopausal women due to potential harm and effects on bone mineral density.

Research protocols typically include careful monitoring of bone health and cardiovascular risk factors during extended studies. Scientists conducting long-term research emphasize the importance of regular health assessments to ensure participant safety and data integrity.

Benefits of Buying from Loti Labs

When researchers need to buy letrozole for legitimate studies, Loti Labs offers competitive pricing with significant cost savings compared to traditional pharmacy sources. Our online ordering system provides 24/7 accessibility with discrete packaging and direct delivery to research facilities.

We offer both brand-name Femara and FDA-approved generic versions at wholesale prices, with additional discounts available on 6-month and 12-month supply orders. This pricing structure helps research institutions save money while maintaining access to high-quality compounds.

Supply Duration	Discount Level	Cost Benefits
1 Month	Standard Price	Baseline
6 Month	Volume Discount	15% savings
12 Month	Maximum Discount	25% savings

Researchers appreciate our streamlined ordering process, which eliminates the need to visit multiple pharmacy locations or deal with insurance complications. The direct-pay system allows research budgets to be managed more effectively, and bulk ordering options help institutions plan their research expenses more efficiently.

Research Use Only Disclaimer

All products offered by Loti Labs, including letrozole, are intended strictly for research use only. These compounds are not intended for human or veterinary consumption, diagnostic purposes, or any form of clinical treatment. Loti Labs provides these products solely to support scientific investigation, laboratory research, and experimental studies.

Researchers and institutions purchasing from Loti Labs must ensure compliance with all applicable laws and regulations governing the use of research chemicals. It is the responsibility of the purchaser to use these compounds only in authorized research settings and to avoid any unauthorized application.

This research use only policy underscores Loti Labs’ commitment to ethical standards and regulatory compliance, ensuring that our products contribute to scientific advancement without compromising safety or legal requirements.

Shipping Policy of Loti Labs

Loti Labs offers same-day shipping for orders placed before 1 PM EST Monday through Friday. Orders placed after 1 PM EST or on weekends will be shipped the next business day, ensuring research timelines are maintained effectively.

Standard shipping delivers within 2-3 business days via USPS First Class Mail, while expedited shipping options are available for additional fees when research schedules require faster delivery. Our shipping team ensures that all packages are properly sealed and labeled to maintain compound integrity during transport.

Research facilities can track their orders through our online system, providing visibility into delivery timelines for better research planning. We understand that research schedules often have critical timing requirements, and our shipping policies are designed to support these needs.

Satisfaction Guarantee

Loti Labs offers a 30-day satisfaction guarantee on all products purchased from us. Research institutions can return any unopened products for a full refund of the purchase price of the unused compounds. Prescription verification must remain valid throughout the return process to ensure continued compliance.

This guarantee provides research facilities with confidence in their purchasing decisions and helps ensure that budget constraints don’t prevent access to quality compounds. The return policy recognizes that research needs can change, and we want to support institutional flexibility while maintaining regulatory compliance.

To initiate a return, research coordinators should contact our support team with order details and return information. The file will be processed quickly to minimize any impact on research budgets or timelines.

Third-Party Testing of Every Batch

Every batch of letrozole sold by Loti Labs undergoes rigorous third-party testing using High-Performance Liquid Chromatography (HPLC) to ensure product purity and accuracy. Our compounds meet or exceed FDA standards for potency and purity, giving researchers confidence in their experimental results.

The testing process involves multiple quality control checkpoints, with detailed documentation provided for each batch. Research institutions receive certificates of analysis that can be included in their research documentation and regulatory submissions.

This commitment to quality assurance helps researchers ensure that their experimental results are based on consistent, high-quality compounds. The independent testing eliminates concerns about batch-to-batch variation that could affect research outcomes or reproducibility.

Comparing Letrozole to Alternative Compounds

Letrozole belongs to the third generation of aromatase inhibitors, alongside anastrozole and exemestane. Research studies have shown all three to be effective, with nuanced differences in response profiles and tolerability. Research suggests that letrozole may be associated with slightly higher rates of musculoskeletal observations, while exemestane, a steroidal inhibitor, may have different effects on bone health parameters.

When researchers compare letrozole to tamoxifen in experimental settings, studies indicate superior outcomes for many research applications, particularly in cases where tamoxifen resistance or intolerance is observed. The choice between compounds often depends on specific research objectives and the characteristics of the study population.

Scientists conducting comparative research should remember that each compound has distinct pharmacological properties that may affect experimental outcomes. Careful consideration of these differences ensures that research protocols are optimized for their specific objectives.

Regulatory Compliance and Quality Assurance

Purchasing letrozole through Loti Labs ensures compliance with all regulatory requirements governing controlled distribution for research applications. Our prescription verification process involves licensed healthcare providers and maintains documentation required for regulatory oversight.

Research institutions must ensure that their use of letrozole aligns with institutional policies and regulatory requirements. This includes proper storage, handling, and documentation procedures that support both research integrity and regulatory compliance.

Quality control measures extend beyond third-party testing to include proper packaging, labeling, and distribution procedures that maintain compound integrity from our facility to your research location. These measures help ensure that research results are based on compounds that meet specified quality standards.

Conclusion

When researchers need to buy letrozole for legitimate research applications, Loti Labs provides a comprehensive solution that combines quality assurance, regulatory compliance, and cost effectiveness. Our commitment to third-party testing ensures that researchers receive compounds that meet the highest purity and potency standards, while our prescription verification process maintains compliance with all regulatory requirements.

The combination of competitive pricing, reliable shipping, and comprehensive support makes Loti Labs the preferred choice for research institutions seeking quality letrozole compounds. Our 30-day satisfaction guarantee and responsive customer support team provide additional confidence for research coordinators managing complex procurement requirements.

For research institutions ready to order letrozole or seeking additional information about our research compound offerings, contact our team to discuss your specific requirements and ensure that your research protocols have access to the highest quality compounds available.

References

1. Novartis Pharmaceuticals Corporation. Femara (letrozole) prescribing information. Available at: https://www.novartis.com
2. National Cancer Institute. Letrozole. Cancer Drug Information. Available at: https://www.cancer.gov/about-cancer/treatment/drugs/letrozole
3. Loti Labs. Buy Letrozole: Quality Research Compounds. Available at: https://www.lotilabs.com
4. American Cancer Society. Hormonal Therapy for Breast Cancer. Available at: https://www.cancer.org/cancer/breast-cancer/treatment/hormonal-therapy.html
5. PubChem. Letrozole Compound Summary. Available at: https://pubchem.ncbi.nlm.nih.gov/compound/Letrozole
6. ClinicalTrials.gov. Studies on Letrozole in Breast Cancer. Available at: https://clinicaltrials.gov/ct2/results?cond=breast+cancer&term=letrozole
7. U.S. Food and Drug Administration (FDA). Generic Drugs: Questions & Answers. Available at: https://www.fda.gov/drugs/generic-drugs/questions-answers-generic-drugs
8. Mayo Clinic. Letrozole (Oral Route). Available at: https://www.mayoclinic.org/drugs-supplements/letrozole-oral-route/description/drg-20066956

For more information on Letrozole please visit Wikipedia.

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Weight	0.1875 lbs
Appearance	Viscous cloudy liquid
Stability	Room Temperature out of direct sunlight
Molar Mass	285.30
CAS Number	112809-51-5
Container	30ml Bottle
Molecular Formula	C17H11N5
Concentration	2.5mg per ML
Terms	This product is sold for research/laboratory usage only. No other uses are permited.

Weight	0.156 lbs