IGF-1 DES 1-3 is a truncated variant of insulin-like growth factor-I (IGF-1) purified to homogeneity from bovine colostrum, human brain, and porcine uterus.

IGF-1 DES 1-3 is available in lyophilized powder form and sold in 1 mg vials.

At Loti Labs, we pride ourselves on stocking high-quality research chemicals. Buy IGF-1 DES 1-3 for sale for research purposes only and not for human consumption.

WHAT IS IGF-1 DES 1-3?

IGF-1 DES 1-3 stands for Insulin-like Growth Factor Desamino 1-3, derived from Escherichia coli. It is a prototype of the parent compound Insulin-like Growth Factor-1 (IGF-1) but differs from it due to the absence of the first three amino acids (Gly-Pro-Glu) located at its N-terminus leaving it with 67 amino acids.

In animal test subjects, IGF-1 DES 1-3 enhanced the growth hormone effect more than IGF-1.

IGF-1 DES 1-3 generally is about 10-fold more potent than IGF-1 at stimulating hypertrophy and proliferation of cultured cells because of the absence of glutamate at position 3. 

Clinical opportunities for IGF-1 DES 1-3 have not yet been evaluated but could apply in catabolic states for treating inflammatory bowel diseases.

STRUCTURE OF IGF-1 DES 1-3

Molecular Formula: C₃₁₉H₄₉₅N₉₁O₉₆S₇

Molecular weight: 7365.4225 g/mol

CAS number: 112603-35-7

MECHANISM OF ACTION

To achieve even higher results than their parent IGF-1, IGF-1 DES 1-3 was used on animal subjects trials. It was observed that it acted by binding to Insulin-like Growth Factor Binding Protein ( IGFBP ) in varying degrees. 

IGF-1 DES 1-3 has a shorter half-life and lasts for as little as 30 minutes. However, that did not reduce its efficacy.

IGF-1 DES 1-3 EFFECTS

Based on available research, the benefits of IGF-1 DES 1-3 may include:

• Cognitive benefits in age
• Improved memory
• Improved immune function
• Accelerate wound healing
• Slows tumor growth

IGF-1 DES 1-3 SIDE EFFECTS

Below are a few side effects associated with IGF-1 DES 1-3 in animal test studies.

• Acromegaly
• Damage to the joints, liver, and heart 
• Muscle pain
• Headaches
• Nausea
• Hypoglycemia

LOOKING FOR WHERE TO BUY IGF-1 DES 1-3 ONLINE

When searching for research peptides online, it is paramount to buy from a trusted laboratory to ensure the integrity of your research. 

Loti Labs offers affordable prices that come with quality control reports. We have in-depth customer support and a generous return policy when you buy IGF-1 DES 1-3 for sale.

Visit our website or contact us today to buy IGF-1 DES 1-3 online.

References:

1. Ballard FJ, Wallace JC, Francis GL, Read LC, Tomas FM (1996). “Des(1-3)IGF-I: a truncated form of insulin-like growth factor-I”. Int. J. Biochem. Cell Biol. 28 (10): 1085–7. doi:10.1016/1357-2725(96)00056-8. PMID 8930132.

2. Yamamoto H, Murphy LJ (1995). “Enzymatic conversion of IGF-I to des(1-3)IGF-I in rat serum and tissues: a further potential site of growth hormone regulation of IGF-I action”. J. Endocrinol. 146 (1): 141–8. doi:10.1677/joe.0.1460141. PMID 7561610.

1. Mario Thevis (13 December 2010). Mass Spectrometry in Sports Drug Testing: Characterization of Prohibited Substances and Doping Control Analytical Assays. John Wiley & Sons. pp. 252–. ISBN 978-1-118-03514-6.