When researchers seek to buy SR9009 for metabolic studies, understanding this compound’s origins and applications becomes essential for making informed purchasing decisions. SR9009, also known as Stenabolic, is sometimes referred to as sr 9009; both names describe the same compound. SR9009 represents a significant advancement in synthetic rev erb agonists developed specifically for research purposes. This comprehensive guide examines the critical factors researchers must consider when evaluating suppliers and ensuring compliance with research use only regulations.
What is SR9009 and Why Buy It?
SR9009 (Stenabolic), also known as stenabolic sr9009, is a synthetic Rev-ErbA agonist originally developed at the Scripps Research Institute by Professor Thomas Burris (Burris TP). This compound functions as a rev erb agonist, targeting the rev erb protein to influence various metabolic pathways within test subjects. Research suggests that SR9009’s mechanism involves binding to rev erbα β, dual nuclear receptors that play crucial roles in regulating circadian rhythms and energy expenditure. Rev erbβ is a circadian nuclear receptor expressed in various cell types within the heart, but studies indicate that it is largely dispensable on its own, and some cardioprotective effects of SR9009 may be independent of rev erbβ signaling.
The compound’s chemical formula C20H24ClN3O4S reflects its complex molecular structure designed to interact with rev erb α receptors. Studies suggest that SR9009 influences gene expression patterns related to metabolism, with particular effects observed in skeletal muscle tissue and liver function. The compound demonstrates a short half life of approximately 4 hours, which researchers must consider when designing experimental protocols. SR9009 has been shown to produce similar effects to other compounds that modulate metabolic activity, muscle growth, and circadian regulation.
Research applications for SR9009 span multiple areas of metabolic investigation. Scientists utilize this compound to examine circadian behavior patterns, energy metabolism pathways, and the interaction between rev erb expression and cellular function. In vitro studies have explored SR9009’s effects on mitochondria function and oxidative capacity, while animal research has investigated its influence on circadian pattern regulation. Studies by Sun Z and Tien CL have further highlighted the importance of these pathways in circadian rhythm and metabolic research.
How SR9009 (Stenabolic) Works
SR9009, commonly known as Stenabolic, operates as a synthetic rev erba agonist, directly targeting the rev erba protein to influence a wide range of physiological processes. By binding to rev erb receptors, SR9009 plays a pivotal role in regulating circadian rhythms, which are the body’s natural cycles governing sleep, metabolism, and energy balance. This regulation extends to the metabolic rate, where SR9009 has been shown to increase energy expenditure and optimize how the body utilizes glucose and lipids.
One of the most notable features of SR9009 is its ability to mimic some of the beneficial effects of exercise. Research indicates that this compound can enhance physical performance and endurance by promoting more efficient energy use in skeletal muscle and the liver. SR9009 decreases the formation of new fat storage cells, supports the breakdown of existing fat, and improves the body’s response to inflammation by modulating macrophage activity. These combined effects contribute to improved metabolism, reduced inflammation, and better overall energy management, making SR9009 a valuable tool for researchers studying metabolic and circadian regulation.
Key Benefits of SR9009
SR9009 offers a range of potential benefits that have made it a focus of metabolic and cardiovascular research. As a rev erba agonist, it has demonstrated the ability to enhance physical performance, support fat loss, and improve overall metabolic health. Studies suggest that SR9009 can lower cholesterol levels, reduce inflammation, and decrease the risk of heart disease by positively influencing gene expression related to circadian rhythms and energy metabolism.
In muscle cells, SR9009 has been shown to increase mitochondrial production, which boosts metabolism, endurance, and strength. This increase in cellular energy production translates to improved exercise capacity and greater resistance to fatigue. The compound’s ability to regulate gene expression also supports healthier circadian rhythms, which are linked to better sleep, mood, and metabolic outcomes. Collectively, these benefits highlight SR9009’s potential to support heart health, enhance energy, and promote a leaner body composition in research settings.
Heart Health and Energy Metabolism Benefits
SR9009 has attracted significant attention for its cardioprotective effects, particularly in experimental models of heart disease. Research has shown that SR9009 can mitigate adverse cardiac remodeling and improve heart function following transverse aortic constriction, a model for pressure overload independent of cardiac rev erb. By regulating rev erbα expression, SR9009 helps maintain a healthy metabolic rate and supports the heart’s ability to adapt to stress.
The compound’s influence on energy expenditure is another key benefit, as it promotes more efficient metabolism and helps reduce the risk of heart disease. Studies conducted at the Scripps Research Institute and other leading institutions have demonstrated that SR9009 can enhance physical performance and support cardiovascular health by optimizing the body’s use of energy. These findings suggest that SR9009 may offer valuable cardioprotective effects and metabolic benefits, making it a promising compound for ongoing research into heart function and disease prevention.
Potential Side Effects of SR9009
While SR9009 has shown promise in preclinical studies, it is important to recognize the potential side effects and limitations associated with its use. As a compound that influences gene expression and metabolic pathways, SR9009 may have unintended effects, particularly with long-term or high-frequency dosing due to its short half life. The safety profile of SR9009 in human usage remains largely uncharacterized, and more research is needed to fully understand its impact on various biological systems.
Researchers should exercise caution when working with SR9009, especially in the context of research purposes involving new compounds or combinations. Potential interactions with other chemicals and the effects on human gene expression are areas that require further investigation. Until more comprehensive data is available, SR9009 should be used strictly for research purposes, and any consideration of its use should involve consultation with qualified professionals and adherence to all relevant safety protocols.
Clinical Research and Data on SR9009
Ongoing clinical research continues to shed light on the effects and mechanisms of SR9009. Studies involving test subjects such as rev erb deficient mice have provided valuable insights into how this compound influences circadian behavior, metabolic rate, and overall health. Data from these animal models indicate that SR9009 can decrease fat mass, improve lipid and glucose profiles, and enhance exercise capacity, supporting its potential benefits for metabolism and physical performance.
Despite these promising findings, more research is needed to confirm the effects of SR9009 in humans and to fully understand its safety and efficacy. For researchers looking to buy stenabolic online for research purposes, it is essential to prioritize quality and purity, ensuring that the compound meets rigorous standards for laboratory use. Adhering to regulatory guidelines and maintaining high standards of documentation will help ensure that research with SR9009 yields reliable and meaningful results, contributing to the growing body of knowledge on this innovative compound.
Where to Buy SR9009 Online
When researchers decide to buy stenabolic online, Loti Labs stands out as a reputable supplier offering high-quality SR9009 with third-party testing and comprehensive Certificates of Analysis. Loti Labs ensures a minimum purity standard of 98%, providing detailed documentation essential for research compliance.
Loti Labs offers SR9009 primarily in capsule formulations containing 10mg per unit. Standard packaging includes 30ml bottles for liquid preparations and 90-capsule containers for solid forms. Researchers should verify shipping regulations in their jurisdictions, but Loti Labs provides reliable shipping services.
This supplier demonstrates transparent business practices with publicly available contact information, clear return policies, and responsive customer service. Loti Labs also offers satisfaction guarantees, reflecting their commitment to quality and customer support.
The verification process includes batch-specific Certificates of Analysis from accredited laboratories, use of pharmaceutical-grade solvents such as PEG400 for liquid formulations, and proper labeling with batch numbers and expiration dates. Glass bottling is employed to preserve the integrity of SR9009, given its fat-soluble nature.
SR9009 Product Specifications When Buying
Understanding product specifications becomes essential when researchers buy SR9009 for laboratory applications. The compound’s molecular weight of 437.94 g/mol and fat-soluble characteristics influence both storage requirements and experimental design considerations. Quality products typically demonstrate minimum 98% purity as verified through high-performance liquid chromatography (HPLC) analysis.
Standard concentration options include:
The compound’s short half life necessitates proper storage conditions to maintain stability and potency. Research-grade SR9009 requires storage in cool, dark environments away from moisture and direct sunlight. Fat-soluble compounds like SR9009 may interact with plastic containers, making glass storage vessels preferable for maintaining chemical integrity.
Third-party testing documentation should accompany all purchases, providing verification of concentration accuracy and purity levels. Reputable suppliers include comprehensive analytical data covering identity confirmation, potency verification, and contamination screening. This documentation proves essential for research compliance and experimental validity.
Price Range and Value Considerations
SR9009 pricing typically ranges from $34 to $172, with costs varying based on quantity, supplier reputation, and included quality assurances. Bulk purchases often provide improved value per milligram, though researchers should balance cost considerations against storage limitations and compound stability over time.
Premium suppliers may charge higher prices but often include valuable services such as enhanced customer support, comprehensive guarantees, and expedited shipping options. When evaluating costs, researchers should consider total value including shipping expenses, particularly for international orders, and available services like technical support and return policies.
Quality assurance measures significantly impact pricing structures. Third-party testing, pharmaceutical-grade solvents, and rigorous documentation practices increase supplier costs but provide essential value for research applications. Researchers should prioritize quality over price when selecting suppliers, as compromised purity or concentration accuracy can invalidate experimental results.
Budget planning should account for ongoing research needs and potential bulk purchase advantages. Many suppliers offer tiered pricing structures rewarding larger orders, though researchers must balance cost savings against the compound’s stability requirements and experimental timelines.
Legal Status and Research Purposes Only
SR9009 maintains legal status as a research chemical in most jurisdictions, available exclusively for laboratory research and in vitro studies. The compound is not approved by regulatory agencies such as the FDA or TGA for human use, therapeutic applications, or dietary supplementation. Researchers must ensure compliance with local regulations governing research chemicals and maintain proper documentation for all purchases.
The legal framework surrounding SR9009 clearly distinguishes between research applications and human usage. This compound cannot be marketed as a dietary supplement, therapeutic agent, or performance enhancement product. Research institutions and individual scientists must verify compliance with institutional policies and local regulations before purchasing.
Documentation requirements vary by jurisdiction but typically include research credentials, institutional affiliations, and intended use declarations. Some suppliers require additional verification for large quantity orders or international shipments. Researchers should maintain detailed records of purchase documentation and batch information for compliance purposes.
International shipping considerations may involve additional regulatory requirements, customs documentation, and potential restrictions in certain countries. Researchers should verify import regulations and shipping restrictions before placing orders to avoid delays or legal complications.
Quality Assurance When Purchasing
Quality assurance represents a fundamental consideration when researchers buy SR9009 for scientific applications. Reliable suppliers provide transparent COAs from accredited testing laboratories, detailing purity levels, concentration accuracy, and contamination screening results. These documents should accompany each batch and include specific analytical methods used for testing.
Critical quality indicators include:
- Purity Verification: Minimum 98% purity confirmed through HPLC analysis
- Concentration Accuracy: Precise measurement of active compound concentration
- Contaminant Screening: Testing for heavy metals, residual solvents, and microbial contamination
- Identity Confirmation: Spectroscopic verification of chemical structure
- Stability Testing: Storage condition validation and expiration dating
Pharmaceutical-grade solvent use distinguishes quality suppliers from less reliable sources. USP-grade solvents like PEG400 ensure product stability and minimize contamination risks. Proper labeling should include batch numbers, manufacturing dates, expiration dates, and storage recommendations.
What to Look for in a Reputable Supplier
Reputable suppliers demonstrate consistent quality practices and transparent business operations. Key indicators include established business histories, publicly available contact information, and responsive customer service teams capable of addressing technical questions about products and testing procedures.
Customer feedback provides valuable insights into supplier reliability and product quality. Look for consistently positive reviews, high overall ratings, and specific comments about product effectiveness and customer service quality. Verified purchase reviews carry more weight than anonymous testimonials.
Payment security and shipping practices reflect supplier professionalism. Quality vendors utilize secure payment processing systems, offer multiple payment options, and provide discreet packaging with proper temperature control for sensitive compounds. Tracking information and delivery confirmation should be standard practice.
Return policies and satisfaction guarantees demonstrate supplier confidence in product quality. Reputable vendors typically offer 30-60 day return windows and may provide replacement products for quality issues. Clear terms and conditions protect both researchers and suppliers in commercial transactions.
Safety and Handling Considerations
SR9009 safety profiles remain under investigation, with more research needed to establish comprehensive toxicological data. Animal studies have indicated potential effects on various organ systems, though complete safety characterization for research applications continues. Researchers should implement appropriate safety protocols when handling this compound.
The compound’s fat-soluble nature influences absorption characteristics and handling requirements. Proper personal protective equipment, including gloves and eye protection, should be used when handling liquid formulations. Adequate ventilation and appropriate disposal procedures help minimize exposure risks during experimental procedures.
Storage safety considerations include maintaining proper temperature conditions, preventing contamination, and ensuring secure storage away from unauthorized access. The short half life necessitates careful timing in experimental design and may require fresh preparation for certain applications.
Research protocols should include safety assessments appropriate for the specific experimental design and test subjects involved. Institutional review boards and safety committees may require additional documentation for experiments involving SR9009, particularly in animal research applications.
Research Applications and Uses
SR9009 research applications span multiple areas of metabolic and circadian rhythm investigation. Scientists utilize this rev erba agonist to examine the relationship between circadian rhythms and energy metabolism, investigating how rev erb expression influences cellular function and gene expression patterns.
Metabolic research applications include studies examining energy expenditure, glucose metabolism, and lipid processing in various tissue types. Research suggests that SR9009 influences mitochondrial function and oxidative capacity, making it valuable for investigating cellular energy production mechanisms. Studies in rev erb deficient mice have provided insights into the compound’s mechanism of action and potential research applications.
Cardiovascular research represents another significant application area. Studies suggest that SR9009 may influence heart function and provide cardioprotective effects in certain experimental models. Notably, SR9009 has shown potential to alleviate heart failure symptoms and prevent cardiac remodeling in heart failure models, highlighting its possible therapeutic role in cardiac dysfunction and pressure overload conditions. Research examining adverse cardiac remodeling and pressure overload conditions has utilized SR9009 to investigate the role of cardiac rev erb in maintaining cardiovascular health.
Circadian biology research utilizes SR9009 to examine how circadian behaviour patterns influence metabolism and physiology. The compound’s interaction with rev erb receptors provides researchers with tools to investigate the molecular mechanisms underlying circadian pattern regulation and their effects on various physiological processes.
Additional research areas include:
- Inflammation Studies: Investigating rev erb’s role in inflammatory response regulation
- Liver Function: Examining metabolic regulation and cholesterol processing
- Exercise Physiology: Understanding the relationship between physical performance and metabolic regulation
- Heart Disease Research: Investigating protective mechanisms against cardiovascular conditions
- Energy Balance: Studying the interaction between metabolism and energy regulation
Many studies on SR9009 include supplementary material, such as echocardiography data and histology images, to provide comprehensive supporting evidence for their findings.
Purchasing Tips and Best Practices
Successful SR9009 procurement requires systematic evaluation of suppliers and products. Begin with small quantity orders to assess supplier reliability and product quality before committing to larger purchases. This approach allows researchers to verify documentation quality, shipping practices, and customer service responsiveness.
Documentation verification should include examining COAs for completeness and accuracy. Quality certificates should detail specific testing methods, include reference standards, and provide clear identification of tested batches. Compare documentation across multiple suppliers to identify quality differences and establish baseline expectations.
Supplier comparison should encompass pricing, quality assurances, shipping options, and customer service capabilities. Create evaluation matrices comparing key factors such as purity levels, testing procedures, return policies, and overall value propositions. Consider long-term research needs when selecting primary suppliers.
Storage preparation becomes critical upon receipt. Ensure appropriate storage conditions are available before ordering, including temperature-controlled environments and proper containment systems. Plan experimental timelines considering the compound’s short half life and stability characteristics.
Record keeping supports both research compliance and quality control. Maintain detailed records of supplier information, batch numbers, purchase dates, and storage conditions. This documentation proves essential for research reproducibility and regulatory compliance.
Consider establishing relationships with multiple qualified suppliers to ensure consistent access to research materials. Supply chain disruptions can impact research timelines, making backup supplier relationships valuable for maintaining experimental continuity.
Bulk purchasing decisions should balance cost savings against storage limitations and compound stability. While larger quantities may offer better per-unit pricing, ensure adequate storage capabilities and realistic usage timelines before committing to significant quantities.
Regular supplier evaluation helps maintain quality standards over time. Monitor supplier performance through ongoing assessment of product quality, delivery reliability, and customer service responsiveness. Document any quality issues or concerns for future reference and supplier evaluation.
Conclusion
Purchasing SR9009 for research applications requires careful consideration of multiple factors including supplier reputation, product quality, legal compliance, and safety requirements. The compound’s status as a research-only chemical necessitates thorough documentation and adherence to regulatory guidelines throughout the procurement process.
Quality assurance emerges as the paramount consideration when researchers buy SR9009, with third-party testing and comprehensive documentation providing essential verification of product integrity. The investment in premium suppliers offering robust quality controls typically proves worthwhile for maintaining experimental validity and research compliance.
Successful procurement strategies emphasize supplier relationship development, systematic quality evaluation, and proper documentation practices. As research continues to expand understanding of SR9009’s mechanisms and applications, maintaining access to high-quality research materials becomes increasingly important for advancing scientific knowledge in metabolic and circadian rhythm research.
Researchers should prioritize compliance with research use only regulations while implementing appropriate safety protocols for handling and storage. By following established best practices and maintaining rigorous quality standards, scientists can ensure reliable access to research-grade SR9009 for their investigational needs.
