YK-11 10mg/ml (30ml)

$59.99
You save

This product is intended as a research chemical only. This designation allows the use of this chemical strictly for in-vitro laboratory testing and experimentation. Human or veterinary use is strictly forbidden. This product is not a drug, food or cosmetic and may not be misbranded, mislabeled or misused as such.

Product Banner

Buy More Save More!

Quantity Discount (%)
1 - 2
3 - 4 3 %
5 - 9 5 %
10 - 14 10 %
15 - 24 15 %
25+ 20 %
Purchase & earn 60 points!
    Disclaimer

    Buy YK-11 Liquid at Loti Labs: Research Compound for Scientific Studies

    YK-11 is an interesting compound in current research with a dual mechanism as a selective androgen receptor modulator and myostatin inhibitor. This unique substance has caught the attention of researchers studying muscle growth pathways and bone tissue engineering applications. For scientists looking to buy YK-11 liquid for their research purposes, understanding the compound’s molecular properties, mechanism of action and sourcing considerations is key to successful experimental results.

    Research chemicals demand the highest standards, especially when investigating compounds with complex biological mechanisms. YK-11’s properties make it a valuable tool for researchers exploring cellular differentiation, protein synthesis pathways and tissue development processes in controlled lab environments.

    Molecular Structure of YK-11

    YK-11 has a well defined molecular profile that sets it apart from other sarms in the research landscape. The compound has:

    Molecular formula: C25H34O6

    Molecular Weight: 382.54 g/mol

    Standard concentration: 10mg/mL

    Appearance: Viscous, cloudy liquid

    Pubchem CID: 44137686

    CAS #: 1370003-76-1

    The molecular structure of YK-11 is derived from dihydrotestosterone (DHT), making it different from non-steroidal compounds in its class. This DHT backbone is responsible for its binding properties and cellular interactions seen in lab studies. Researchers working with this substance will find the standard concentration of 10mg per milliliter is optimal for experimental protocols and solution stability.

    The compound’s appearance as a viscous, cloudy liquid is due to its suspension in specialized solvents designed to ensure accuracy and stability. This form allows for precise measurement and administration in research settings, making it perfect for scientists who need exact quantity control in their studies.

    Mechanism of Action

    YK-11 works as a dual mechanism as a selective androgen receptor modulator and myostatin inhibitor. Research shows this compound increases follistatin expression which promotes muscle growth in research models. YK-11 blocks myostatin, a protein that naturally limits muscle tissue growth and stimulates follistatin production both systemically and locally.Lab studies show potential for bone tissue engineering through osteoblast differentiation and Akt protein phosphorylation for androgen mediated bone development. The compound works through specific cellular pathways that researchers can study to understand tissue development processes.

    Selective Androgen Receptor Modulation

    The compound is a partial agonist at androgen receptors, showing tissue selective targeting in research models. Unlike traditional androgens, YK-11 does not promote the full N/C-terminal interaction required for full transcriptional activation, which may explain its tissue selective effects seen in studies.

    Myostatin Inhibition Pathway

    Research shows YK-11 upregulates follistatin expression, a glycoprotein that binds and neutralizes myostatin. This removes natural limits on cellular growth processes making it useful for researchers studying tissue development mechanisms. The compound’s ability to modulate this pathway gives researchers a tool to study cellular differentiation processes.

    Animal studies have shown this dual action produces different cellular responses compared to other compounds in the same class, giving researchers opportunities to explore new biological pathways and their applications in tissue engineering research.

    Research Studies

    Animal studies have shown YK-11’s protective effects against sepsis induced muscle wasting and reduced mortality in septic mice through cytokine inflammation suppression. Research has shown acceleration of osteoblast cell proliferation and mineralization when combined with DHT. YK-11 induces bone specific markers like osteoprotegerin and osteocalcin making it a promising candidate for bone tissue engineering research applications.

    Muscle Tissue Research

    The Kanno et al. (2013) study showed significant findings on YK-11’s effects on C2C12 mouse myoblasts, increased myogenic differentiation and hypertrophy through follistatin upregulation. These results give researchers valuable data to understand cellular mechanisms and their applications in tissue research.

    Research shows YK-11 treatment had more pronounced effects than DHT alone, suggesting unique cellular interactions that researchers can explore further. The compound’s effect on protein synthesis pathways gives scientists opportunities to study fundamental biological processes.

    Bone Development Studies

    Yatsu et al. (2018) conducted comprehensive research showing YK-11’s promotion of osteoblast proliferation and mineralization in MC3T3-E1 cells. The study showed increased expression of bone specific markers including osteoprotegerin and osteocalcin, giving researchers evidence of the compound’s potential in bone tissue engineering applications.These results suggest YK-11 may be a useful tool for researchers studying bone development. The compound’s ability to induce specific cellular markers makes it useful for scientists studying tissue differentiation.

    Tissue Wasting Protection

    Animal studies have shown protective effects against sepsis induced tissue wasting, with reduced mortality and decreased pro-inflammatory cytokine signaling. These results give scientists insight into anti-cachexia mechanisms and their applications in disease models.

    Storage and Safety

    YK-11 liquid solution is supplied in glass bottles with fixed droppers to prevent contamination and ensure accurate measurement. The product is suspended in USP grade PEG400 for stability and accuracy. Glass packaging prevents plasticizer leaching and maintains compound integrity. Store in a cool, dry place away from direct sunlight and keep tightly sealed when not in use for maximum stability.

    Packaging Specifications

    Blue glass bottles protect the compound from light degradation and prevent chemical interactions that can occur with plastic containers. Fixed droppers eliminate contamination risks and give researchers consistent measurement capabilities for reproducible results.

    USP grade suspension ensures optimal solubility and stability, maintains compound integrity throughout storage periods. This pharmaceutical grade solvent system gives researchers confidence in their experimental protocols and results.

    Storage Protocols

    Proper storage conditions are crucial for compound stability and research accuracy. Researchers should store at 2-8°C if possible, room temperature storage is acceptable for short term use.

    The bottle should be tightly sealed when not in use to prevent moisture absorption and concentration consistency. These safety protocols ensure researchers receive products meeting the highest grade standards throughout their intended use period.

    Why Buy from Loti Labs

    Individual 30mL vials containing 300mg total YK-11 are priced competitively. Bulk discounts available for larger research projects: 10% off for 5-9 vials, 15% off for 10-19 vials, 20% off for 20-49 vials. All YK-11 products from Loti Labs undergo rigorous quality control and are manufactured to the highest industry standards to ensure research accuracy and reproducibility.

    Competitive Pricing

    Researchers will find Loti Labs offers transparent pricing that fits their research needs. The bulk discount structure provides significant savings for institutions doing large scale research or long term projects. These pricing options make it easier for researchers to add quality compounds to their cart while managing their research budget.First time customers receive the same high quality products and competitive pricing as repeat customers so everyone gets premium compounds regardless of purchase history.

    Quality Control

    Every batch is tested to ensure products meet purity standards. We stand behind our quality so you can trust your results and have consistency across multiple experiments.

    We focus on the highest quality manufacturing to give you products for your most demanding protocols. This means you get reliable, reproducible results in your research.

    Loti Labs products are for Research Use Only

    All products sold by Loti Labs are research chemical only. This means use is strictly for in-vitro laboratory testing and experimentation. Human consumption or veterinary use is strictly forbidden. This product is not a dietary supplement, food or cosmetic and may not be misbranded, mislabeled or misused as such.

    Research Only Importance

    The research only designation means customers understand the intended use and regulatory status of these compounds. This classification protects both the researcher and supplier by setting clear boundaries around approved uses.

    Researchers must have their institutional review boards and safety committees approve all experimental protocols involving these compounds. Proper documentation and safety protocols are still required for responsible research.

    Compliance

    The substance remains legal through research only guidelines. This designation allows researchers to get compounds for legitimate scientific purposes while staying compliant with regulations.

    Institutions purchasing these products should have proper documentation and storage protocols in place consistent with research chemical handling guidelines. This ensures continued access to quality compounds for research.

    Loti Labs Shipping

    Loti Labs ships same day for orders placed before 1pm EST Monday through Friday. Orders placed after 1pm EST or on weekends will ship the next business day.

    Expedited Processing

    Same day shipping means you get your compounds fast, minimizing delays in your research timeline. This helps you stay on track with your project and meet your experimental deadlines.

    Weekend orders will be processed the following business day, so you don’t have to wait for time sensitive research. Contact customer service if you have questions about shipping timeframes or special handling requirements.

    Packaging and Handling

    All products ship in protective packaging to keep your compounds safe during transit. Temperature controlled shipping options are available if you need specific storage conditions.Tracking information allows researchers to get real time updates on their shipments so they can plan their experimental protocols accordingly. This transparency helps researchers coordinate their work and ensure proper compound handling upon receipt.

    Guarantee

    Loti Labs offers a 30 day guarantee on all products. Simply return any unopened products to us for a full refund of the purchase price of the unused products.

    Customer Protection

    The guarantee shows the company stands behind product quality and gives researchers protection for their investment. This policy allows scientists to buy with confidence knowing they have recourse if products don’t meet their research needs.

    Unopened products are fully returnable so researchers can adjust their orders based on changing experimental requirements. This is especially useful for research projects with evolving protocols or funding considerations.

    Return Process

    Customers can initiate returns by contacting customer service within the guarantee period. The simple return process minimizes administrative hassle so researchers can focus on their science.

    Documentation requirements are minimal, we prioritize customer satisfaction and continued research relationships. This helps build trust between researchers and suppliers in the competitive research chemical market.

    Third Party Tested Every Batch

    Every batch of products sold by Loti Labs is third party tested by accredited American laboratories to ensure product purity and accuracy. All YK-11 products are 98% minimum purity and come with a Certificate of Analysis.

    Quality Control

    Independent laboratory testing ensures unbiased assessment of product quality and purity. These accredited facilities use advanced analytical techniques to verify compound identity and quantify purity levels.

    98% minimum purity is above many industry standards, so researchers can trust their results. This high standard ensures reproducibility and accuracy across different research applications.

    Certificate of Analysis

    Each batch comes with documentation verifying compound specifications and purity levels. Researchers can review these certificates to confirm product quality and maintain proper laboratory documentation.

    The certificates have detailed analytical data researchers can use to validate their experimental protocols and results. This transparency supports scientific rigor and helps researchers stay compliant with institutional requirements.

    Analytical Methods

    Testing laboratories use validated analytical methods including HPLC and mass spectrometry to ensure compound identification and quantification. These methods give researchers confidence in product authenticity and purity.

    Regular calibration and method validation ensures consistent testing standards across all batches. This systematic approach to quality control gives researchers reliable results and experimental consistency.

    Research shows YK-11 is a valuable tool for scientists studying cellular mechanisms, tissue development and protein synthesis pathways. As a selective androgen receptor modulator and myostatin inhibitor YK-11 offers researchers a unique opportunity to explore complex biological processes.

    When you buy YK-11 liquid from Loti Labs you get products made to the highest quality standards with full quality control. Competitive pricing, fast shipping and satisfaction guarantee makes Loti Labs the best choice for research institutions and individual scientists.

    For researchers looking for high grade compounds for their research Loti Labs has the quality, consistency and support for successful research. Contact us to discuss your research needs and find the right products for your next research study.

    References

    1. Kanno Y, et al. (2013). Selective androgen receptor modulator, YK11, regulates myogenic differentiation of C2C12 myoblasts by follistatin expression. Biol Pharm Bull. 36(9):1460-5.
    2. Yatsu T, et al. (2018). Selective androgen receptor modulator, YK11, up-regulates osteoblastic proliferation and differentiation in MC3T3-E1 cells. Biol Pharm Bull. 41(3):394-398.
    3. Narayanan R, et al. (2018). Selective androgen receptor modulators in preclinical and clinical development. Nucl Receptor Res. 5:101320.
    4. Lee SJ, Gharbi A, Shin JE, Jung ID, Park YM. (2021). Myostatin inhibitor YK11 as a preventative health supplement for bacterial sepsis. Biochem Biophys Res Commun. 543:1-7.
    5. Yatsu T, Kusakabe T, Kato K, Inouye Y, Nemoto K, Kanno Y. (2018). Selective androgen receptor modulator, YK11, up-regulates osteoblastic proliferation and differentiation in MC3T3-E1 cells. Biol Pharm Bull. 41(3):394-398.
    6. Biol Pharm Bull. (2011). 34(3):318–23. PMID 21372378.

    For more information on YK-11 please visit Wikipedia.


    Weight 0.1875 lbs
    Appearance Viscous cloudy liquid
    Stability Room Temperature out of direct sunlight
    Molar Mass 430.541
    CAS Number 1370003-76-1
    Container 30ml Bottle
    Molecular Formula C25H34O6
    Concentration 10mg per ML
    Terms This product is sold for research/laboratory usage only. No other uses are permited.
    Reviews

    Product Index

    Capsules

    Peptides

    Research Liquids

    Total: $0.00
    Product Index
    X