Pramipexole 2mg/ml (30ml)

Buy Pramipexole Liquid: Premium-Grade Dopamine Agonist Solutions

Research into dopaminergic pathways demands precise, reliable compounds that meet stringent laboratory standards. When investigators need to buy pramipexole liquid for their studies, the quality and consistency of the research compound directly impacts experimental outcomes. Pramipexole, a non-ergoline dopamine agonist, has become an essential tool for scientists studying dopamine receptor mechanisms, neurodegeneration models, and cellular signaling pathways.

This comprehensive guide examines the molecular properties, research applications, and procurement considerations for pramipexole liquid formulations. Whether you’re conducting in vitro receptor binding assays or exploring neuroprotective mechanisms in cellular models, understanding the specifications and sourcing options for this research compound is crucial for successful experimental design.

Molecular Structure of Pramipexole

Pramipexole represents a sophisticated example of modern pharmaceutical chemistry, with its complete chemical designation as (S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole. The compound’s molecular formula C10H17N3S reflects its unique structural architecture, while its molecular weight of 211.33 g/mol positions it favorably for both cellular uptake studies and receptor binding research.

Property	Value
Chemical Name	(S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole
Molecular Formula	C10H17N3S
Molecular Weight	211.33 g/mol
PubChem CID	119570
CAS Number	104632-26-0

The benzothiazole ring system forms the structural backbone of pramipexole, with strategic substitutions that confer its distinctive pharmacological profile. The amino group at the 2-position and the propylamino group at the 6-position contribute to the compound’s receptor selectivity, while the tetrahydro designation indicates reduction at specific ring positions. This structural flexibility enhances water solubility compared to fully aromatic analogs, making liquid formulations particularly suitable for research applications.

Understanding these molecular characteristics becomes essential when researchers shop for pramipexole liquid, as the compound’s chemical properties directly influence its stability, solubility, and experimental utility across diverse research protocols.

Mechanism of Action

Pramipexole functions as a non-ergoline dopamine agonist with remarkable specificity for the D2 subfamily of dopamine receptors, demonstrating particular affinity for the D3 receptor subtype. This selective binding profile distinguishes it from other dopamine agonists and contributes to its unique research utility in dopaminergic studies.

Research suggests that the compound’s preferential D3 receptor binding offers distinct advantages in experimental models. The D3 receptors concentrate primarily in limbic brain regions associated with mood regulation and motor control, making pramipexole an invaluable tool for investigating these neural pathways. Unlike ergot-derived dopamine agonists, pramipexole’s non-ergoline structure eliminates concerns about fibrotic complications that can confound long-term research studies.

At the cellular level, pramipexole activation of D2/D3 receptors leads to adenylyl cyclase inhibition, modulating downstream signaling cascades relevant to neuroprotection and synaptic plasticity. Laboratory investigations have demonstrated that this mechanism contributes to the compound’s efficacy in various experimental paradigms, from protecting neurons against oxidative stress to modulating neurotransmitter release patterns.

The substance’s unique receptor profile has made it particularly valuable for researchers studying conditions like Parkinson disease models and restless legs syndrome mechanisms. Past customers sharing their research findings often highlight pramipexole’s consistency in producing reproducible results across different experimental conditions, making it a reliable choice for investigators requiring standardized dopaminergic modulation.

Research Studies and Applications

Extensive laboratory investigations have positioned pramipexole as a cornerstone compound for dopaminergic research. Scientists utilize this substance across multiple experimental paradigms, from basic receptor characterization to complex disease modeling studies. The compound’s versatility stems from its well-characterized pharmacology and reliable performance in diverse research settings.

In Vitro Research Applications

Cell culture studies frequently employ pramipexole to investigate dopamine receptor signaling pathways. Researchers use the compound in receptor binding assays to determine affinity constants and functional responses at cloned human dopamine receptors. These studies have revealed important insights into receptor subtype selectivity and downstream signaling mechanisms.

Neuronal culture experiments represent another significant application area. Scientists investigating neuroprotection mechanisms often expose cultured neurons to toxins like MPTP or 6-OHDA, then assess pramipexole’s protective effects. Research suggests that the compound can reduce oxidative stress markers and inhibit apoptotic pathways in these experimental models.

In Vivo Research Models

Animal studies have extensively characterized pramipexole’s effects in behavioral and biochemical research paradigms. Investigators use the compound to model dopaminergic dysfunction in rodent and primate systems, generating valuable data about motor function, cognitive processes, and neurochemical changes.

Behavioral research has examined how pramipexole affects locomotor activity, reward processing, and motor coordination in laboratory animals. These studies provide crucial foundational data for understanding dopaminergic mechanisms and have informed the development of more sophisticated experimental approaches.

The compound’s established safety profile in research settings has enabled long-term studies examining chronic dopaminergic modulation. Past customers frequently report successful implementation of extended treatment protocols, collecting product reviews that emphasize the substance’s stability and consistent efficacy across prolonged experimental timelines.

Storage and Safety Considerations

Proper storage protocols are essential for maintaining pramipexole liquid integrity throughout research projects. The compound requires specific environmental conditions to preserve its chemical stability and biological activity. Laboratories must implement appropriate storage and handling procedures to ensure consistent experimental results.

Storage Requirements

Store pramipexole liquid formulations at controlled room temperature, specifically between 20°C and 25°C. Protect the substance from direct light exposure, as pramipexole demonstrates photosensitive properties that can lead to degradation under intense illumination. Maintain the original container with the cap tightly secured to prevent contamination and evaporation.

Commercial liquid formulations typically contain pramipexole at standardized concentrations of 0.5 mg/mL or 2 mg/mL, depending on specific research requirements. These precise concentrations eliminate the need for manual dissolution procedures, reducing preparation time and improving experimental consistency.

Laboratory Safety Protocols

Research use of pramipexole liquid requires standard laboratory safety measures. Personnel should wear appropriate protective equipment, including gloves and safety goggles, when handling the substance. While pramipexole is not classified as a controlled substance, its biological activity at low concentrations necessitates careful handling procedures.

The compound’s pharmacological properties mean that accidental exposure can potentially affect the central nervous system, potentially causing symptoms like drowsiness or coordination difficulties. Laboratories should maintain proper ventilation and implement spill response procedures as part of their safety protocols.

Emergency procedures should include immediate contact with appropriate healthcare professionals if accidental exposure occurs. Laboratory personnel should be advised that pramipexole can interact with other medications and substances, making medical consultation essential in exposure incidents.

Benefits of Buying from Loti Labs

Loti Labs provides research-grade pramipexole liquid formulations designed specifically for laboratory applications. The company’s commitment to quality and consistency has established them as a trusted supplier for institutional research programs and individual investigators. Several key advantages distinguish their products in the competitive research chemical market.

Standardized Formulations

Loti Labs offers pramipexole liquid at validated, standardized concentrations that enhance experimental reproducibility. This precision eliminates the variability associated with manual compound preparation, ensuring consistent results across different research protocols. The availability of multiple concentration options accommodates diverse experimental requirements, from high-throughput screening assays to detailed mechanistic studies.

The liquid form provides particular advantages for cell culture applications and in vivo injection studies, where solubility and dosage accuracy are critical factors. Researchers can directly incorporate the compound into experimental systems without additional preparation steps, streamlining laboratory workflows and reducing potential sources of error.

Quality Assurance

Every batch of pramipexole liquid undergoes rigorous third-party testing using high-performance liquid chromatography (HPLC) to verify purity and concentration accuracy. This analytical approach ensures batch-to-batch consistency, a crucial factor for longitudinal studies and multi-site research collaborations. Certificates of analysis are available upon request, providing documentation that supports institutional quality assurance requirements.

The company’s quality control measures extend beyond chemical analysis to include proper packaging and storage protocols. Temperature-controlled shipping maintains product integrity during transit, while opaque containers protect against light-induced degradation. These comprehensive quality measures contribute to the 96% customer satisfaction rating that reflects Loti Labs’ commitment to research excellence.

Ordering and Availability

Loti Labs maintains substantial stock levels to ensure product availability for time-sensitive research projects. The catalog includes convenient 30 mL bottles suitable for most laboratory applications, with bulk ordering options available for larger institutional programs. Custom concentration requests can often be accommodated, providing flexibility for specialized research requirements.

The ordering process is designed for efficiency, with same-day shipping available for orders placed before 1 PM EST, Monday through Friday. This rapid fulfillment helps researchers maintain project timelines and reduces delays in critical experimental phases.

Research Use Only Compliance

All pramipexole liquid products from Loti Labs are designated strictly for research use only, a regulatory classification that defines their intended applications and limitations. This designation is crucial for compliance with FDA guidelines and international regulations governing laboratory chemicals. Understanding these restrictions is essential for proper procurement and use.

Regulatory Framework

The research use only classification prohibits human use of these substances outside of approved clinical research settings. Products cannot be promoted or supplied for medical, food, or cosmetic applications, and their labeling must clearly state their intended research purpose. This regulatory framework protects both suppliers and researchers while ensuring appropriate use of biologically active compounds.

Laboratories purchasing pramipexole liquid must acknowledge these restrictions and implement appropriate controls to prevent unauthorized use. Institutional review boards and research oversight committees typically require documentation of proper procurement and storage procedures as part of their approval processes.

Laboratory Compliance

Research institutions must maintain detailed records of pramipexole procurement, storage, and use to demonstrate compliance with research use only requirements. These records should include purchase documentation, storage logs, and experimental protocols that clearly define the compound’s intended research applications.

Personnel training is another critical compliance element. Laboratory staff should understand the limitations associated with research use only substances and the importance of preventing any applications outside approved research contexts. Regular training updates help maintain awareness of regulatory requirements and proper handling procedures.

Shipping and Customer Service

Loti Labs has developed comprehensive shipping and customer service policies designed to support research operations while maintaining product quality throughout the distribution process. These policies reflect the company’s understanding of research timelines and the critical importance of reliable chemical supply chains.

Shipping Protocols

The company’s shipping policy emphasizes both speed and product integrity. Orders received before 1 PM EST on business days are shipped the same day, while later orders are processed the following business day. All pramipexole liquid shipments utilize temperature-controlled packaging to prevent heat exposure during transit, preserving compound stability and potency.

Tracking information is provided for all shipments, allowing researchers to monitor delivery progress and plan laboratory activities accordingly. The company’s shipping partners are selected based on their ability to maintain proper storage conditions and deliver products promptly to research facilities.

Customer Support

Loti Labs offers comprehensive customer support to address technical questions, ordering inquiries, and product information requests. The support team includes personnel with scientific backgrounds who can provide informed guidance about product specifications and applications. This expertise is particularly valuable for researchers who are new to pramipexole studies or need clarification about storage and handling requirements.

Satisfaction Guarantee

The company stands behind its products with a 30-day satisfaction guarantee on unopened items. This policy reflects confidence in product quality while providing researchers with recourse if products fail to meet their specifications. Returns must remain unopened to maintain quality assurance throughout the supply chain, ensuring that all distributed products meet the same high standards.

The 96% customer satisfaction rating demonstrates the effectiveness of Loti Labs’ quality control measures and customer service approach. Past customers consistently report positive experiences with product quality, shipping reliability, and technical support, contributing to the company’s reputation in the research community.

Pricing and Value Considerations

When researchers evaluate options to buy pramipexole liquid, pricing represents just one factor in a comprehensive value assessment. The total cost of research compounds includes not only the purchase price but also considerations like shipping, handling, storage requirements, and the potential costs associated with product variability or quality issues.

Loti Labs’ pricing structure reflects the comprehensive quality control measures and customer service features that support successful research outcomes. While price comparisons are important, researchers should evaluate the total value proposition, including product consistency, documentation availability, and technical support capabilities.

The availability of bulk ordering options provides cost advantages for larger research programs, while the standardized liquid formulations can reduce overall project costs by eliminating preparation time and minimizing waste. These factors contribute to the overall value proposition for research institutions seeking reliable pramipexole supplies.

Technical Specifications and Documentation

Researchers require detailed technical information to properly incorporate pramipexole liquid into their experimental protocols. Loti Labs provides comprehensive documentation that supports experimental design and regulatory compliance requirements across diverse research settings.

Analytical Data

Each batch of pramipexole liquid includes detailed analytical data generated through HPLC analysis. This information confirms the compound’s identity, concentration, and purity, providing the documentation needed for publication and regulatory submissions. The analytical methods employed follow pharmaceutical industry standards, ensuring data quality and reproducibility.

Certificates of analysis are available upon request and include comprehensive impurity profiles, moisture content, and stability data. This documentation is particularly important for institutional buyers who must maintain detailed quality assurance records for their research programs.

Stability Information

Long-term stability studies provide guidance for proper storage and use timelines. Pramipexole liquid formulations demonstrate excellent stability when stored under recommended conditions, with minimal degradation observed over extended periods. This stability supports research projects that require consistent compound quality over months or years.

Temperature excursion studies help researchers understand the compound’s tolerance for brief storage deviations, providing practical guidance for laboratory operations. These data are particularly valuable for researchers working in facilities with variable environmental controls or those conducting field studies.

Conclusion

The decision to buy pramipexole liquid for research applications requires careful consideration of multiple factors, from molecular specifications to supplier reliability. Pramipexole’s unique pharmacological profile as a non-ergoline dopamine agonist with D3 receptor selectivity makes it an invaluable tool for dopaminergic research, but only when sourced from suppliers who maintain appropriate quality standards.

Loti Labs addresses the critical requirements of research institutions through standardized formulations, comprehensive quality control, and customer service designed for scientific applications. The company’s commitment to research use only compliance ensures that researchers can procure and use pramipexole liquid with confidence in both product quality and regulatory adherence.

For scientists investigating dopamine receptor mechanisms, neuroprotection pathways, or disease models involving conditions like Parkinson disease or restless legs, reliable access to high-quality pramipexole liquid is essential. The compound’s established efficacy in diverse experimental paradigms, combined with its excellent safety profile in research settings, positions it as a cornerstone tool for advancing our understanding of dopaminergic neurobiology.

Whether your research focuses on basic receptor characterization, cellular protection mechanisms, or complex behavioral studies, choosing the right supplier for pramipexole liquid can significantly impact your experimental outcomes. Loti Labs’ comprehensive approach to quality, service, and compliance provides the foundation for successful research programs that advance scientific knowledge while maintaining the highest standards of laboratory practice.

Visit the Loti Labs website to explore their catalog of research compounds and discover how their pramipexole liquid formulations can support your next breakthrough in dopaminergic research.

References

1. Parkinson’s Foundation. Dopamine Agonists (Pramipexole, Ropinirole). Available at: https://www.parkinsons.org.uk/information-and-support/dopamine-agonists-pramipexole-ropinirole
2. Bayview Pharmacy. Pramipexole Dihydrochloride 0.5 mg/ml Oral Suspension. Available at: https://www.bayviewrx.com/formulas/Pramipexole-Dihydrochloride-0-5-mg-ml-Oral-Suspension-Parkinson-s-Disease-Restless-Legs-Syndrome-Secondary-Parkinsonism-Tardive-Dyskinesia-Depression
3. Loti Labs. Buy Pramipexole Liquid for Research Use. Available at: https://www.lotilabs.com/pramipexole-liquid
4. PubChem. Pramipexole. Available at: https://pubchem.ncbi.nlm.nih.gov/compound/Pramipexole
5. CalPac Lab. Pramipexole Dihydrochloride 1g. Available at: https://www.calpaclab.com/pramipexole-dihydrochloride-1g-each/spc-tci-p2073-1g
6. Melanotan Express. Pramipexole 2mg/ml. Available at: https://www.melanotanexpress.com/product/pramipexole-2mg-ml-30ml-50-bottles-2
7. Evolution Peptides. Pramipexole 2mg per ml x 30 ml. Available at: https://evolutionpeptides.com/products/pramipexole-2mg-per-ml-x-30-ml

Please consult these sources for further detailed information on pramipexole, its applications, and handling guidelines.

For more information on Pramipexole please visit Wikipedia

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Weight	0.1875 lbs
Appearance	Viscous transparent liquid
Stability	Room Temperature out of direct sunlight
Molar Mass	211.33
CAS Number	104632-26-0
Container	30ml Bottle
Molecular Formula	C10H17N3S
Concentration	2mg per ML
Terms	This product is sold for research/laboratory usage only. No other uses are permited.