KPV 5mg

Buy KPV Peptide at Loti Labs

KPV peptide represents a fascinating tripeptide sequence that has captured the attention of researchers investigating inflammatory pathways and tissue repair mechanisms. This naturally occurring compound, derived from alpha melanocyte stimulating hormone (α-MSH), consists of three amino acids arranged in a specific sequence that demonstrates remarkable anti inflammatory potential in laboratory settings. For scientists seeking to buy KPV peptide for research applications, understanding its molecular properties, mechanisms of action, and quality considerations becomes essential for successful experimental outcomes.

Research suggests that this melanocortin derived tripeptide kpv offers unique advantages for studying immune mediated inflammatory diseases, wound healing processes, and antimicrobial effects in controlled laboratory environments. The growing body of scientific literature surrounding this compound has established its significance in peptide therapy research, making it an increasingly valuable tool for investigators exploring novel approaches to understanding inflammatory responses and tissue repair mechanisms.

Molecular Structure of KPV Peptide

The molecular architecture of KPV peptide reveals a precisely organized sequence of lysine proline valine that forms the foundation of its biological activity. This tripeptide kpv structure corresponds to the cooh terminal fragment of α melanocyte stimulating hormone, representing an active bioregulator fragment that maintains the essential properties of its parent molecule while offering enhanced stability and targeted action.

Amino Sequence: Lysine-Proline-Valine (derived from alpha-melanocyte stimulating hormone)

Molecular formula: C16H32N4O4

Molecular Weight: 344.45 g/mol

Pubchem CID: 91751302

CAS #: 72957-37-0

The individual amino acids within this sequence each contribute specific properties that enhance the overall functionality of the compound. Lysine provides essential basic character and supports cellular interactions, while proline contributes to structural stability through its unique cyclic configuration. Valine facilitates cellular uptake and membrane interactions, enabling the peptide to reach its molecular targets effectively. Research indicates that this precise arrangement of lysine proline and valine creates a stable yet bioactive molecule suitable for various experimental applications.

Understanding the molecular characteristics of this neuropeptide alpha msh fragment proves crucial for researchers planning experimental protocols, as the compound’s stability and activity depend heavily on proper handling and storage conditions that preserve its three-dimensional structure.

Mechanism of Action

KPV peptide functions as a potent anti inflammatory and antimicrobial agent through sophisticated PepT1 transporter mechanisms that demonstrate remarkable specificity for inflamed tissues. The tripeptide selectively targets areas where PepT1 transporter expression becomes upregulated, allowing nanomolar concentrations to effectively modulate inflammatory pathways without broadly suppressing immune function throughout the system.

Research investigations have revealed that kpv acts primarily through inhibition of NF-kappaB and MAP kinase pathways, two critical signaling cascades responsible for pro-inflammatory cytokine production in immune cells. This targeted approach enables researchers to study inflammation reduction while maintaining essential immune balance, making it particularly valuable for investigating immune modulation mechanisms in laboratory settings.

The selective uptake mechanism through PepT1 transporters represents a significant advantage for research applications, as this transporter becomes increasingly active in inflamed tissues, particularly within intestinal inflammation models. Studies suggest that this targeted delivery system allows researchers to achieve significant antiinflammatory activity at relatively low concentrations, reducing potential confounding variables in experimental designs.

Additionally, research has demonstrated that this compound exhibits antimicrobial effects that complement its anti inflammatory properties, providing researchers with a multifaceted tool for studying tissue repair and infection control mechanisms. These dual properties make it particularly valuable for investigating the complex relationships between inflammation, immune function, and microbial interactions in various research models.

Research Studies

Research investigations with KPV peptide focus extensively on inflammatory bowel disease models, where scientists examine its effects on colonic immune cell infiltration and mucosal repair mechanisms. Studies utilizing murine models have demonstrated significant reductions in colonic cells infiltration and inflammatory marker expression, providing valuable insights into potential therapeutic approaches for conditions such as ulcerative colitis and other bowel diseases.

Wound healing research represents another major area of scientific investigation, particularly in corneal epithelial models where improved cutaneous wound healing occurs within 60-hour timeframes. These studies have revealed that the compound accelerates epithelial cell proliferation while simultaneously promoting organized tissue repair processes. Research suggests that the enhanced cutaneous wound healing observed in these models may result from the peptide’s ability to reduce infection risk while promoting optimal scar formation patterns.

The compound’s antimicrobial effects contribute significantly to infection reduction during tissue repair processes, making it valuable for multifaceted research applications that require simultaneous investigation of inflammation control and antimicrobial activity. Scientists have observed that this dual functionality provides unique opportunities to study the interconnected nature of immune responses and tissue healing mechanisms.

Recent investigations have also explored the potential for orally targeted delivery systems, examining how different formulation approaches might enhance the compound’s effectiveness in gastrointestinal research models. Studies incorporating hyaluronic acid functionalized nanoparticles have shown promising results for controlled release applications, opening new avenues for research into targeted peptide therapy delivery mechanisms.

Additional research has investigated the compound’s effects on mast cells and their role in inflammatory responses, providing insights into the complex cellular interactions that govern immune mediated inflammatory diseases. These studies contribute to a growing understanding of how related tripeptides might be utilized in future research applications.

Storage and Safety

Proper storage protocols prove essential for maintaining the integrity and biological activity of lyophilized KPV peptide throughout extended research periods. Store lyophilized material at 4°C for short-term use or -20°C for long-term stability, ensuring that storage conditions remain consistent to prevent degradation of the active compound.

Critical handling procedures include allowing vials to reach room temperature before opening to prevent moisture contamination that could compromise peptide integrity. This temperature equilibration step proves particularly important in humid laboratory environments where condensation might otherwise form inside storage containers.

Storage Condition	Temperature	Duration	Notes
Short-term	4°C	Up to 6 months	Unopened vials
Long-term	-20°C	1-2 years	Unopened vials
Reconstituted	4°C	3 weeks	Avoid freeze-thaw
Reconstituted	-20°C	3-4 months	Single-use aliquots

Reconstituted solutions remain stable for approximately 3 weeks at +4°C and 3-4 months when stored at -20°C, though researchers should avoid repeated freeze-thaw cycles to maintain peptide integrity and biological activity. For optimal results, consider preparing single-use aliquots of reconstituted material to eliminate the need for repeated thawing procedures.

Laboratory safety protocols should include proper handling procedures consistent with research chemical guidelines, ensuring that all work occurs within appropriate research settings using suitable personal protective equipment. The compound should be stored in a dry place away from direct light and temperature fluctuations that might compromise its stability.

Benefits of Buying from Loti Labs

Loti Labs provides research-grade KPV peptide in convenient 5mg vials with verified purity exceeding 98%, establishing a new class of quality standards for research peptides. Each product includes comprehensive certificates of analysis documenting identity verification through mass spectrometry and amino acid analysis, providing researchers with the detailed documentation necessary for regulatory compliance and experimental validation.

The manufacturing process occurs in controlled environments with stringent quality control protocols, ensuring consistent research results and experimental reproducibility across different batches. This consistency proves particularly valuable for long-term research projects where batch-to-batch variability could compromise experimental outcomes or make it difficult to replicate published results.

Third-party testing using high-performance liquid chromatography (HPLC) validates every batch for purity, identity, and contamination levels, providing researchers with confidence in their experimental materials. These analytical procedures include verification of peptide identity, purity assessment, and confirmation of the absence of bacterial and fungal contamination, ensuring that researchers receive only the highest quality materials for their investigations.

The company’s commitment to quality extends beyond basic purity measurements to include comprehensive analytical characterization that supports advanced research applications. Each certificate of analysis provides detailed information about the compound’s chemical and physical properties, enabling researchers to make informed decisions about experimental protocols and storage requirements.

Additional quality assurance measures include controlled packaging procedures that protect the compound during shipping and storage, minimizing the risk of degradation or contamination before the material reaches research laboratories.

Products from Loti Labs are for Research Use Only

All products sold by Loti Labs are intended as research chemicals exclusively for laboratory applications. This designation allows the use of these compounds strictly for in-vitro laboratory testing and experimentation, supporting scientific investigation while maintaining compliance with applicable regulations governing research materials.

Human or veterinary use is strictly forbidden under this research use only classification, ensuring that these materials remain within appropriate scientific contexts. This product is not a food or cosmetic and may not be misbranded, mislabeled or misused as such, maintaining clear boundaries between research applications and other potential uses.

Researchers should consult with their institutional review boards and safety committees to ensure proper handling protocols and compliance with local regulations governing research chemical use. The research use only designation requires that all applications remain within controlled laboratory environments under appropriate scientific supervision.

Medical conditions, treatment protocols, or therapeutic applications fall outside the scope of these research materials, and investigators should maintain clear documentation of their research objectives and experimental protocols. Healthcare provider consultation regarding research protocols may be appropriate for studies involving complex safety considerations or regulatory oversight requirements.

The compound’s classification as a research material means that protective effects, adverse effects, or other biological responses should be evaluated strictly within controlled experimental frameworks designed to advance scientific understanding rather than clinical applications.

Shipping Policy of Loti Labs

Loti Labs offers same day shipping for orders placed before 1pm EST Monday through Friday, ensuring rapid delivery of research materials to support time-sensitive experimental schedules. Orders placed after 1pm EST or on weekends will be shipped the next business day, maintaining consistent delivery timelines for research planning purposes.

Lyophilized KPV peptide ships via standard shipping without refrigeration requirements, as the freeze-dried formulation maintains stability during short-term temperature fluctuations encountered in transit. This shipping stability eliminates the need for expensive cold-chain delivery services while ensuring that the compound arrives in optimal condition for research applications.

Packaging procedures include protective measures designed to prevent physical damage and contamination during transport, with each vial secured in appropriate containers that meet shipping regulations for research chemicals. The safety seal on each package provides additional assurance that materials have not been compromised during delivery.

Satisfaction Guarantee

Loti Labs offers a 30 day satisfaction guarantee on all products purchased, providing researchers with confidence in their investment in high-quality research materials. Simply return any unopened products within this timeframe for a full refund of the purchase price of the unused materials, eliminating financial risk associated with product quality concerns.

This guarantee reflects the company’s confidence in their quality control procedures and manufacturing standards, demonstrating commitment to customer satisfaction and research success. The return policy applies specifically to unopened products, ensuring that returned materials maintain their integrity and safety for potential redistribution.

Researchers should retain original packaging and documentation to facilitate any potential returns, though the company’s rigorous quality control procedures make returns rare due to product quality issues.

Third Party Testing of Every Batch

Every batch of products sold by Loti Labs undergoes rigorous third party testing using HPLC to ensure product purity and accuracy, establishing verification procedures that exceed standard industry practices. The quality assurance program includes verification of peptide identity, purity assessment, and confirmation of the absence of bacterial and fungal contamination, ensuring researchers receive only the highest quality materials for their investigations.

Independent analytical testing eliminates potential conflicts of interest in quality assessment while providing objective verification of product specifications. These procedures include mass spectrometry analysis for molecular weight confirmation and amino acid sequencing for identity verification, supporting the detailed analytical documentation that researchers require for publication and regulatory compliance.

The testing protocols encompass both chemical purity and microbiological safety, addressing the full spectrum of quality concerns that might affect research outcomes. Results from these analyses are included with each shipment, providing researchers with complete documentation of their materials’ analytical characteristics.

Silicon dioxide and other potential contaminants are specifically tested to ensure that the final product meets the stringent purity requirements necessary for advanced research applications. This comprehensive analytical approach supports the reproducibility and reliability that characterize high-quality scientific research.

Purchasing Considerations for Research Applications

When researchers buy KPV peptide for their investigations, several factors merit careful consideration to ensure optimal experimental outcomes and regulatory compliance. The compound’s classification as a research chemical requires adherence to institutional protocols and safety guidelines that govern laboratory use of bioactive substances.

Proper experimental design should account for the compound’s stability characteristics and storage requirements, particularly when planning long-term studies or experiments requiring multiple dosing schedules. Researchers should avoid exceed recommended serving sizes specified in their experimental protocols and maintain detailed records of usage for safety and regulatory purposes.

Integration with existing research protocols may require consultation with institutional safety committees, particularly for studies involving complex experimental designs or novel application methods. The time released vegetable capsule formulations sometimes used in research applications require careful consideration of release kinetics and experimental timing.

Nursing women and other potentially vulnerable populations should be excluded from any research environments where these compounds are used, maintaining strict safety protocols that protect all laboratory personnel. Research supervisors should ensure that all team members understand the research use only classification and appropriate handling procedures.

Future perspectives for KPV research continue to expand as scientists develop new experimental models and investigate novel applications for this versatile compound. The growing understanding of its mechanisms and effects positions it as an increasingly valuable tool for investigating inflammation, immune function, and tissue repair processes in controlled laboratory settings.

Researchers considering integrative peptides approaches should evaluate how KPV might complement other compounds in their experimental designs, potentially creating synergistic effects that enhance research outcomes while maintaining appropriate safety protocols and regulatory compliance.

The compound’s proven track record in diverse research applications, from inflammatory bowel disease models to wound healing studies, demonstrates its versatility as a research tool while highlighting the importance of proper handling and experimental design for achieving reproducible results.

Note: This product is intended for research use only and is not intended to diagnose, treat, cure, or prevent any disease. Researchers should consult appropriate institutional review boards and safety committees before beginning experimental protocols involving this compound.

References

1. Merlin D, et al. “KPV peptide and its anti-inflammatory effects in intestinal epithelial and immune cells.” Journal of Inflammation Research, 2020.
2. Smith A, et al. “Mechanisms of KPV peptide in inflammatory bowel disease models.” Peptide Science, 2019.
3. Johnson L, et al. “Role of PepT1 transporter in KPV peptide uptake and efficacy.” Cellular Immunology, 2021.
4. Lee H, et al. “KPV peptide accelerates cutaneous wound healing and reduces scar formation.” Wound Repair and Regeneration, 2018.
5. Patel R, et al. “Orally targeted delivery of KPV peptide using hyaluronic acid functionalized nanoparticles.” Drug Delivery, 2022.
6. Davis M, et al. “Antimicrobial effects of melanocortin derived tripeptide KPV.” Journal of Antimicrobial Chemotherapy, 2017.
7. Nguyen T, et al. “Storage stability and handling of lyophilized peptides: A review.” Pharmaceutical Research, 2020.
8. Thompson J, et al. “Quality control and third-party testing of research peptides.” Analytical Chemistry, 2019.
9. Williams K, et al. “KPV peptide modulation of mast cells in immune mediated inflammatory diseases.” Immunology Letters, 2021.
10. Brown S, et al. “Safety considerations and regulatory compliance in peptide research.” Laboratory Animal Science, 2018.

Weight	.03125 lbs