NAD+ 500mg

Buy NAD+ for Research: Purchase High-Quality Nicotinamide Adenine Dinucleotide

Research into cellular processes has revealed nicotinamide adenine dinucleotide (NAD+) as a fundamental coenzyme essential for various cellular processes in living cells. Scientists seeking to buy NAD+ for laboratory investigations must consider multiple factors including molecular specifications, storage requirements, and supplier quality standards. This comprehensive guide examines the critical aspects researchers need to understand when purchasing NAD+ for scientific studies.

As research continues to explore NAD+ involvement in cellular energy production, dna repair mechanisms, and metabolic pathways, the demand for high-quality research compounds has increased significantly. Understanding the molecular properties and proper handling procedures ensures optimal results in laboratory settings while maintaining compliance with research use only guidelines.

Molecular Structure of NAD+

Chemical Name: Nicotinamide Adenine Dinucleotide

Molecular Formula: C₂₁H₂₇N₇O₁₄P₂

Molecular Weight: 663.43 g/mol

PubChem CID: 5893

CAS #: 53-84-9

The molecular structure of NAD+ consists of two nucleotides joined via phosphate groups, with one nucleotide containing an adenine base and the other containing nicotinamide. This coenzyme exists in two primary forms: NAD+ (oxidized) and NADH (reduced), where the ‘+’ designation indicates the oxidized state crucial for redox reactions within cellular systems.

Research has demonstrated that NAD stands for nicotinamide adenine dinucleotide, representing one of the most abundant and important coenzymes found in human cells and other living organisms. The precise molecular structure enables its function as an electron carrier in numerous biological processes, making it invaluable for researchers studying cellular metabolism and energy production pathways.

Mechanism of Action

NAD+ functions as a coenzyme in redox reactions, playing a key role in cellular metabolism and cellular energy production processes. Research suggests this compound participates in over 500 enzyme reactions throughout biological systems, serving as a crucial electron carrier in mitochondrial electron transport chains that convert nutrients into cellular energy.

Studies indicate NAD+ serves as a substrate for several enzyme classes, including sirtuins that regulate various cellular processes, PARPs involved in dna repair mechanisms, and ADP-ribosyltransferases. These interactions position NAD+ as one of the primary therapeutic targets for researchers investigating cellular function and metabolic pathways.

The aging process appears closely linked to NAD+ availability in cells, with research suggesting declining levels may contribute to age related degenerative diseases and reduced cellular function. Animal models have demonstrated that maintaining vital levels of this coenzyme can support healthy aging processes and enhance overall cellular health in laboratory settings.

Research has also explored NAD+ involvement in:

• Circadian rhythm regulation
• Gene expression control
• Stress resistance mechanisms
• Cellular level repair processes
• Cell metabolism optimization

Research Studies

Current research explores NAD+ supplementation effects across multiple therapeutic targets and cellular processes. Animal models suggest that increasing NAD+ availability may support healthy aging mechanisms and enhance cellular health parameters in laboratory settings.

Preclinical studies have examined various forms of NAD+ delivery, including sublingual tablets, nasal spray formulations, and nad injection protocols. Research suggests these different supplements may influence energy levels and cognitive function through distinct metabolic pathways, though human applications require further investigation.

Research Area	Animal Model Findings	Potential Applications
Metabolic Function	Improved glucose regulation	Type 2 diabetes research
Neuroprotection	Enhanced stress resistance	Cognitive decline studies
Cardiovascular Health	Improved cardiac resilience	Heart health investigations
DNA Repair	Enhanced PARP activation	Cancer cells research

Studies examining nicotinamide riboside and nicotinamide mononucleotide as NAD+ precursors have shown promising results in boosting cellular NAD+ levels. Research suggests these compounds may offer potential health benefits for cognitive health and mental clarity, though optimal recommended dose protocols remain under investigation.

Recent research has also explored nad iv therapy and nad therapy protocols in controlled laboratory settings. These studies examine how different delivery methods affect cellular uptake and metabolism, providing valuable insights for researchers developing supplementation protocols.

Storage and Safety

Proper storage protocols are essential when researchers buy NAD+ for laboratory use. The compound should be maintained in cool, dry conditions away from direct sunlight to preserve molecular stability. Research grade NAD+ typically arrives as lyophilized powder requiring specific storage temperatures between 2-8°C for short-term use and -20°C for long-term preservation.

Laboratory handling requires strict adherence to safety protocols, including:

• Airtight container storage
• Moisture protection measures
• Temperature monitoring systems
• Personal protective equipment use
• Proper ventilation in work areas

Research chemicals require careful handling to prevent digestive upset or other adverse reactions in laboratory environments. Scientists must follow established protocols for research use only compounds, ensuring compliance with federal and state regulations governing laboratory chemical usage.

Storage considerations also extend to prepared solutions, which may require different handling protocols than powder forms. Many forms of NAD+ demonstrate varying stability profiles, necessitating specific storage requirements based on formulation and intended research applications.

Benefits of Buying from Loti Labs

Loti Labs distinguishes itself through comprehensive quality assurance measures designed specifically for researchers who buy NAD+ for scientific studies. Every batch undergoes rigorous third-party testing using High Performance Liquid Chromatography (HPLC) to verify purity and molecular composition, ensuring researchers receive contamination-free materials for their investigations.

Third Party Testing of Every Batch

Quality control represents a fundamental concern for researchers examining cellular processes and metabolic pathways. Loti Labs addresses this through independent laboratory testing of each production batch, providing researchers with detailed analytical data supporting their experimental protocols. This testing methodology ensures consistent results across research studies and supports reproducible scientific outcomes.

Shipping Policy of Loti Labs

Loti Labs offers same day shipping for orders placed before 1pm EST Monday through Friday. Orders placed after 1pm EST or on weekends will be shipped the next business day. This reliable delivery schedule supports research timelines and ensures investigators receive their compounds when needed for time-sensitive experiments.

The shipping protocols include:

• Temperature-controlled packaging for compound stability
• Tracking information for order monitoring
• Secure packaging to prevent contamination
• Documentation supporting research use only guidelines

Satisfaction Guarantee

Loti Labs offers a 30 day satisfaction guarantee on all products purchased from us. Simply return any unopened products to us for a full refund of the purchase price of the unused products. This policy provides researchers with confidence in their purchases while supporting budget management for research institutions.

Additional benefits include subscription discounts for regular orders and free shipping options for qualifying purchases, making it more economical for laboratories conducting ongoing research into aging, cellular health, and metabolic processes.

Products from Loti Labs are for Research Use Only

All of the products sold by Loti Labs are intended as a research chemical only. This designation allows the use of this chemical strictly for in-vitro laboratory testing and experimentation. Human or veterinary use is strictly forbidden. This product is not a substance for therapeutic use and may not be misbranded, mislabeled or misused as such.

Researchers must understand that NAD+ compounds from Loti Labs are specifically formulated for laboratory investigations into cellular mechanisms, aging processes, and metabolic pathways. These research chemicals support scientific studies examining how NAD+ influences various cellular processes but are not intended for human consumption or therapeutic applications.

The research use only designation ensures compliance with regulatory requirements while supporting legitimate scientific investigations. Qualified researchers, including those in academic institutions, pharmaceutical companies, and biotechnology firms, utilize these compounds to advance understanding of cellular function and potential therapeutic targets.

Healthcare professional oversight and institutional approval may be required for certain research protocols involving NAD+ compounds. Researchers should consult with their institutional review boards and compliance departments to ensure proper authorization for their intended studies.

Studies examining the aging process, cellular energy production, and dna repair mechanisms benefit from access to high-quality research compounds. When scientists buy NAD+ from reputable suppliers like Loti Labs, they gain access to materials that support rigorous scientific investigation while maintaining compliance with research regulations.

The research community continues investigating how NAD+ supplementation might support healthy aging and enhance cellular health. These studies require pure, well-characterized compounds to ensure reliable results and support the development of future therapeutic approaches targeting age related degenerative diseases.

For researchers ready to buy NAD+ for their scientific investigations, Loti Labs provides the quality assurance, regulatory compliance, and customer support necessary for successful research outcomes. Contact our research team for technical specifications, bulk pricing information, and guidance on storage protocols for your specific research applications.

References

1. Braidy N, Berg J, Clement J, Khorshidi F, Poljak A, Jayasena T, Grant R, Sachdev P. Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes. Antioxid Redox Signal. 2019 Jan 10;30(2):251-294.
2. Covarrubias AJ, Perrone R, Grozio A, Verdin E. NAD+ metabolism and its roles in cellular processes during ageing. Nat Rev Mol Cell Biol. 2021 Feb;22(2):119-141.
3. Conlon NJ. The Role of NAD+ in Regenerative Medicine. Plast Reconstr Surg. 2022 Oct 1;150(4 Suppl):41S-48S.
4. Mills KF, Yoshida S, Stein LR, Grozio A, Kubota S, Sasaki Y, Redpath P, Migaud ME, Apte RS, Uchida K, Yoshino J. Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice. Cell Metab. 2016 Dec 13;24(6):795-806.
5. San-Millán I. The Key Role of Mitochondrial Function in Health and Disease. Antioxidants (Basel). 2023 Apr 18;12(4):782.
6. Campbell JM. Supplementation with NAD+ and Its Precursors to Prevent Cognitive Decline across Disease Contexts. Nutrients. 2022 Aug 7;14(15):3231.
7. Braidy N, Villalva MD, van Eeden S. Sobriety and Satiety: Is NAD+ the Answer? Antioxidants (Basel). 2020 May 14;9(5):425.
8. Dellinger RW, Santos SR, Morris M, Evans M, Alminana D, Guarente L, Marcotulli E. Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: A randomized, double-blind, placebo-controlled study. Npj Aging Mech Dis. 2017 Nov 30;3:17.
9. Yoshino J, Baur JA, Imai S. NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR. Cell Metab. 2018 Mar 6;27(3):513-528.
10. Grozio A, Mills KF, Yoshino J, Bruzzone S, Sociali G, Tokizane K, Lei HC, Cunningham R, Sasaki Y, Migaud ME. Slc12a8 is a nicotinamide mononucleotide transporter. Nature Metabolism. 2019;1(1):47-57.

Weight	.06250 lbs