CJC-1295 W/ DAC 2mg

CJC-1295 with DAC for sale is available in lyophilized powder form, in 2mg vials. It is only for research purposes and not for human consumption.

CJC-1295 with DAC: A Comprehensive Overview

CJC-1295 with DAC is a synthetic peptide analog of growth hormone-releasing hormone (GHRH) that has garnered significant attention in the scientific community for its unique properties and potential research applications. This peptide is designed to stimulate the production and release of growth hormone (GH) from the pituitary gland, making it a valuable tool for studying hormonal regulation and metabolic processes.

Structure and Mechanism

CJC-1295 with DAC is a modified version of the first 29 amino acids of GHRH, with four strategic amino acid substitutions that enhance its stability and resistance to enzymatic degradation. These modifications occur at positions 2, 8, 15, and 27 of the peptide chain, replacing the original amino acids with D-alanine, glutamine, alanine, and leucine, respectively.

The “DAC” in CJC-1295 with DAC stands for “Drug Affinity Complex,” a biochemical component that significantly extends the peptide’s half-life. This complex involves the attachment of a lysine derivative to the C-terminus of the peptide, allowing it to bind to plasma proteins and remain active in the body for an extended period.

Pharmacokinetics

One of the most notable features of CJC-1295 with DAC is its remarkably long half-life compared to other GHRH analogs. While natural GHRH has a half-life of only about 7 minutes, CJC-1295 with DAC boasts a half-life of approximately 6-8 days. This extended duration of action makes it an excellent candidate for studying long-term effects of growth hormone stimulation in research settings.

Research Implications

Studies have shown that CJC-1295 with DAC may significantly increase plasma GH and insulin-like growth factor 1 (IGF-1) levels in animal models. These elevations can persist for extended periods, with some research indicating that IGF-1 levels may remain elevated for up to 28 days after administration.

The peptide’s ability to stimulate GH release has led to its investigation in various areas of scientific research, including:

1. Metabolic studies: CJC-1295 with DAC may be useful in examining lipid metabolism, energy expenditure, and glucose homeostasis.
2. Cellular growth and repair: The peptide’s influence on GH and IGF-1 levels makes it a valuable tool for studying cellular proliferation and tissue regeneration.
3. Endocrine system regulation: Researchers can use CJC-1295 with DAC to investigate the complex interplay between various hormones and their effects on physiological processes.
4. Aging and longevity research: The peptide’s potential effects on growth hormone levels have made it interesting for studies related to aging and age-related conditions.

Potential Applications

While CJC-1295 with DAC is primarily a research peptide, its unique properties have led scientists to speculate about its potential applications in various fields:

1. Metabolic research: The peptide’s effects on GH and IGF-1 levels make it a promising candidate for studying metabolic disorders and obesity-related conditions.
2. Tissue repair studies: Its potential to stimulate cellular growth and regeneration could be valuable in research on wound healing and tissue damage.
3. Endocrine system investigations: CJC-1295 with DAC may help researchers better understand the complexities of hormonal regulation and its impact on various physiological processes.
4. Anti-aging research: The peptide’s ability to potentially modulate growth hormone levels has made it interesting for studies related to aging and longevity.

In conclusion, CJC-1295 with DAC is a fascinating synthetic peptide that offers unique opportunities for scientific research. Its extended half-life, coupled with its ability to stimulate growth hormone release, makes it a valuable tool for investigating various aspects of physiology, metabolism, and cellular biology. As research continues, this peptide may provide valuable insights into hormonal regulation and its wide-ranging effects on biological systems.

References:

1. Wikipedia. “CJC-1295.” https://en.wikipedia.org/wiki/CJC-1295
2. DC Report. “CJC-1295 with DAC: A Speculation into Research Implications.” https://www.dcreport.org/2024/09/13/cjc-1295-with-dac-a-speculation-into-research-implications/

Citations:

1. https://en.wikipedia.org/wiki/CJC-1295
2. https://www.dcreport.org/2024/09/13/cjc-1295-with-dac-a-speculation-into-research-implications/
3. https://www.ebar.com/story.php?ch=news&id=336147
4. https://downloads.regulations.gov/FDA-2024-N-4777-0009/attachment_6.pdf

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For more information on CJC-1295 with DAC please visit Wikipedia.