CJC-1295 W/ DAC 2mg

Please Note: All products sold by Loti Labs are for research/laboratory use only. This description has been compiled from numerous sources and is not intended as advice of any kind nor does Loti Labs make any potential claims of the use of this product. Nothing in this description should be construed as advice or claims. Human use is strictly forbidden. 

CJC 1295 with DAC for sale from Loti Labs

CJC 1295 is a synthetic peptide used in research to boost growth hormone release. This article covers its mechanism, applications, and handling guidelines.

Key Takeaways

• CJC-1295 is a synthetic peptide that enhances growth hormone release, primarily used for research purposes, not for human use.
• Its Drug Affinity Complex (DAC) significantly extends the half-life of CJC-1295, allowing for prolonged stimulation of growth hormone and less frequent dosing in research studies.
• CJC-1295 has versatile applications in various research fields, including metabolic studies, cellular growth, tissue repair, and endocrine regulation, making it a valuable tool for scientific inquiry.

Understanding CJC-1295

CJC-1295 is a synthetic analogue of somatocrinin, a growth hormone-releasing hormone (GHRH) that plays a pivotal role in promoting growth hormone release. Classified as a synthetic peptide and a GHRH analogue, CJC-1295 functions as a growth hormone releasing factor, enhancing growth hormone release and improving pharmacokinetics such as half-life. Its primary utilization in scientific studies revolves around exploring its effects on growth hormone dynamics and associated physiological processes. Importantly, CJC-1295 is sold strictly for research purposes and is never intended for human use.

For researchers, grasping the intricacies of CJC-1295 helps in leveraging its capabilities. This synthetic peptide stimulates the production and release of growth hormone by mimicking natural growth hormone releasing peptide hormones.

Administering CJC-1295, particularly in its long-acting form, allows for extended study of growth hormone dynamics, offering valuable insights into its potential applications.

Mechanism of Action

CJC-1295 stimulates growth hormone release by acting on growth hormone-releasing hormone receptors. Binding to specific receptors in the anterior pituitary gland, it prompts a pulsatile increase in growth hormone production, effectively mimicking the body’s natural cycles and sustaining hormone release over time. This process is influenced by growth hormone GH.

Key amino acids like ser, ala, arg, lys, tyr, ile, phe, thr, and leu in CJC-1295’s peptide sequence are vital for its binding and activity.

Administering CJC-1295 once daily administration via subcutaneous injection ensures efficient delivery to the pituitary gland, enhancing growth hormone output and impacting overall endocrine health by modulating hormonal secretions.

Role of Drug Affinity Complex (DAC)

The Drug Affinity Complex (DAC) revolutionizes CJC-1295 administration by significantly enhancing its stability and half-life, extending its bloodstream presence from minutes to several days. With a half-life of about 6-8 days, CJC-1295 with DAC ensures prolonged growth hormone stimulation, facilitating extended observation periods for researchers.

By enhancing the peptide’s binding to albumin, a plasma protein, DAC significantly extends CJC-1295’s half-life in the bloodstream. This transformation into a long-acting analogue reduces dosing frequency, enabling more consistent growth hormone levels and stable, reliable research outcomes.

Research Applications of CJC-1295

CJC-1295’s role as a growth hormone secretagogue receptor opens the door to a multitude of research applications. As a synthetic version of a growth hormone-releasing hormone, it aids in the stimulation of growth hormone secretion, which is essential for various physiological processes. Additionally, growth hormone secretagogues contribute to this stimulation.

CJC-1295’s potential spans metabolic research, tissue repair studies, endocrine investigations, and anti-aging research. Researchers explore its effects on body composition, cellular growth, and endocrine regulation, making it a versatile tool for laboratory research. Studies using the ghrh knockout mouse have shown that treatment with CJC-1295 normalizes growth and metabolic responses, highlighting its potential therapeutic applications.

Metabolic Studies

In metabolic studies, CJC-1295 is being explored for its potential to influence fat metabolism and body composition. Research involving CJC-1295 has shown a tendency to maintain balanced levels of subcutaneous fat mass and lean mass in animal models, suggesting a possible impact on body composition. The extended half-life of CJC-1295 may allow for sustained growth hormone release, which could mimic natural cycles and potentially prolong metabolic effects. Observations in studies have indicated changes in lipid metabolism and body composition, which are areas of interest for those studying obesity, weight management, and metabolic disorders.

Preclinical studies show that CJC-1295 influences various metabolic pathways, offering insights into the complex interactions between growth hormone and metabolism. By maintaining elevated growth hormone levels over extended periods, researchers can investigate long-term metabolic changes and their health implications.

Cellular Growth and Repair

CJC-1295 is a subject of interest in studies focused on cellular proliferation and tissue repair. Its potential influence on muscle growth and injury recovery has been noted, as it may enhance natural growth hormone production, potentially impacting muscle mass and fat mass. Some studies suggest improvements in lean muscle mass and overall body composition, highlighting its possible value for muscle growth and rehabilitation research.

By potentially supporting somatotroph cells and normalizing growth, CJC-1295 is being explored for its role in cellular growth and repair studies. Its ability to stimulate growth hormone production might aid tissue repair and regeneration, offering intriguing possibilities for research into injury recovery and muscle development.

Endocrine System Regulation

Primarily through its impact on growth hormone secretion, CJC-1295 plays a significant role in regulating the endocrine system. Acting on the anterior pituitary gland, it stimulates growth hormone release, crucial for maintaining hormonal balance. Its ability to increase growth hormone levels profoundly influences various physiological processes, including metabolism, growth, and development.

Research highlights CJC-1295’s potential as a therapeutic agent in endocrine regulation studies. By modulating growth hormone secretion and interacting with secretagogue receptors, CJC-1295 provides valuable insights into the complex dynamics of hormonal balance and its effects on overall health.

These findings underscore CJC-1295’s importance in clinical endocrinology and its potential applications in treating endocrine disorders.

Specifications and Stability of CJC-1295

Grasping the specifications and stability of CJC-1295 is essential for its effective use in research. Its molecular composition, represented by the formula C165H269N47O46, underscores its complex structure and potential for targeted biological activity.

Proper storage and handling are vital to maintain the peptide’s stability and ensure reliable research outcomes.

Molecular Details

CJC-1295 boasts a detailed molecular structure, with a formula of C151H246N44O42S and a molecular mass of approximately 3647.25 g/mol. This synthetic peptide consists of a sequence length of 30 amino acids, including key residues such as gln, leu, ser, ala, and asp, ala, ile, phe, which play a crucial role in its binding and activity. The precise arrangement of these amino acids allows CJC-1295 to effectively mimic the activity of natural growth hormone-releasing hormones, enhancing its potential for research applications.

Another variant of its molecular formula, C152H252N44O42, further highlights the peptide’s complexity and the importance of understanding its molecular details for effective research use. This detailed molecular composition ensures that CJC-1295 can interact with specific receptors and exert its desired biological effects, making it a valuable tool for scientific studies.

Storage and Handling

Proper storage and handling of CJC-1295 preserve its stability and effectiveness. It should be stored at -20°C for long-term preservation and can remain stable at room temperature for a limited time. Keeping CJC-1295 in a cool, dry place (2 to 8°C) and protecting it from light and moisture maintains its stability.

Containers for peptide storage should be clean and chemically inert to prevent contamination, ensuring the peptide remains pure and effective for research. After use, resealing peptide vials under a dry inert gas atmosphere maintains stability and prevents degradation.

Adhering to these storage and handling guidelines is essential for researchers to obtain reliable and reproducible results.

Benefits of Using CJC-1295 in Research

Using CJC-1295 in research offers manifold benefits, primarily due to its ability to enhance growth hormone secretion and maintain elevated hormone levels over extended periods. This prolonged effect, facilitated by the Drug Affinity Complex (DAC), allows for less frequent administration and more stable research outcomes.

Researchers can leverage these benefits to conduct long-term studies and gather comprehensive data on various physiological processes.

Prolonged Stimulation

CJC-1295 is noted for its potential to stimulate growth hormone release over an extended period, attributed to its extended half-life of up to 8 days. As a long-acting analog, it may allow for continuous stimulation and sustained effects, potentially reducing the need for multiple doses and enabling researchers to observe long-term outcomes. A single injection of CJC-1295 is suggested to maintain elevated growth hormone levels, offering the possibility of prolonged and consistent effects.

The extended half-life and potential for prolonged stimulation could make CJC-1295 a valuable subject for studies on cell proliferation, muscle growth, and overall metabolic health. By possibly mimicking the body’s natural pulsatile secretion of growth hormone, CJC-1295 may provide a more accurate representation of physiological processes, offering researchers data and insights.

Enhanced Insulin Like Growth Factor (IGF-1) Levels

Research suggests that CJC-1295 may elevate levels of insulin-like growth factor 1 (IGF-1), which is important for cellular growth, repair, and overall metabolic health. In studies involving healthy adults, subcutaneous administration of CJC-1295+DAC has been associated with a dose-dependent increase in growth hormone (GH) and IGF-1 levels. By potentially promoting growth hormone secretion, CJC-1295 might indirectly influence IGF-1 concentrations in the bloodstream, which could support muscle growth, tissue repair, and various developmental processes.

Research indicates that IGF-1 levels can remain elevated for up to 28 days after CJC-1295 administration, providing a sustained period of enhanced cellular activity and recovery. This prolonged elevation benefits studies focused on muscle growth, bone density, and overall metabolic health, allowing researchers to observe long-term effects of IGF-1 on various physiological processes.

How to Purchase CJC-1295 Online

Purchasing CJC-1295 online requires careful consideration to ensure a high-quality product for research needs. Identifying trustworthy suppliers who provide comprehensive product information and customer support is crucial.

By thoroughly researching suppliers and understanding legal restrictions, researchers can confidently purchase CJC-1295 and utilize it effectively in their studies.

Evaluating Product Quality

Choosing a reputable supplier is paramount to ensuring the quality and purity of CJC-1295. Look for suppliers with positive reviews from other researchers and clear certifications indicating product quality, often a testament to the supplier’s commitment to providing high-quality research materials.

Proper storage and handling of CJC-1295 are also essential. Ensure the supplier follows stringent storage protocols, such as keeping the peptide in a cool, dry place and protecting it from light. These measures help maintain the peptide’s stability and effectiveness, ensuring reliable research outcomes.

Summary

In summary, CJC-1295 with DAC is a powerful tool for scientific research, offering significant benefits in the fields of metabolic studies, cellular growth and repair, and endocrine system regulation. Its synthetic nature, combined with the Drug Affinity Complex, provides prolonged stimulation and enhanced IGF-1 levels, making it invaluable for long-term studies. Understanding its mechanism of action, proper storage and handling, and the legal considerations involved in its purchase are crucial for maximizing its potential in research settings.

As you embark on your research journey with CJC-1295, remember to source it from reputable suppliers who provide comprehensive product information and adhere to legal standards. By doing so, you can ensure the quality and integrity of your research, paving the way for groundbreaking discoveries and advancements in various scientific fields.

Frequently Asked Questions

What modifications were made to the original growth hormone releasing hormone (GHRH) in CJC-1295 with DAC?

CJC-1295 with DAC features four strategic amino acid substitutions at positions 2, 8, 15, and 27 of the original GHRH structure. This modification enhances its stability and efficacy.

What potential applications are speculated for CJC-1295 with DAC?

CJC-1295 with DAC is speculated to have potential applications in metabolic research, tissue repair, endocrine system investigations, and anti-aging research. These areas highlight its promise in advancing health and longevity.

What is CJC-1295 with DAC primarily used for?

CJC-1295 with DAC is primarily used for research purposes only and is not intended for human consumption.

How does CJC-1295 with DAC differ from natural GHRH in terms of half-life?

CJC-1295 with DAC significantly differs from natural GHRH as it has a much longer half-life of approximately 6-8 days, whereas natural GHRH only lasts about 7 minutes. This extended duration enhances its effectiveness in stimulating growth hormone release.

How long can IGF-1 levels remain elevated after administration of CJC-1295 with DAC?

IGF-1 levels can remain elevated for up to 28 days following the administration of CJC-1295 with DAC. This prolonged elevation contributes to its effectiveness in promoting growth and recovery.

References:

1. Wikipedia. “CJC-1295.” https://en.wikipedia.org/wiki/CJC-1295
2. DC Report. “CJC-1295 with DAC: A Speculation into Research Implications.” https://www.dcreport.org/2024/09/13/cjc-1295-with-dac-a-speculation-into-research-implications/

Citations:

1. https://en.wikipedia.org/wiki/CJC-1295
2. https://www.dcreport.org/2024/09/13/cjc-1295-with-dac-a-speculation-into-research-implications/
3. https://www.ebar.com/story.php?ch=news&id=336147
4. https://downloads.regulations.gov/FDA-2024-N-4777-0009/attachment_6.pdf

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Weight	0.05 lbs