YK-11 10mg/ml (30ml)

Buy YK-11 Liquid at Loti Labs: Premium Research Compound for Scientific Studies

YK-11 represents a fascinating compound in contemporary research, distinguished by its dual mechanism as both a selective androgen receptor modulator and myostatin inhibitor. This unique substance has captured the attention of researchers investigating muscle growth pathways and bone tissue engineering applications. For scientists seeking to purchase high-quality YK-11 liquid for their research purposes, understanding the compound’s molecular properties, mechanisms of action, and sourcing considerations proves crucial for successful experimental outcomes.

The field of research chemicals demands the highest quality standards, particularly when investigating compounds with complex biological mechanisms. YK-11’s distinctive properties make it an invaluable tool for researchers exploring cellular differentiation, protein synthesis pathways, and tissue development processes in controlled laboratory environments.

Molecular Structure of YK-11

YK-11 presents a well-defined molecular profile that distinguishes it from other sarms in the research landscape. The compound exhibits the following key characteristics:

Molecular formula: C25H34O6

Molecular Weight: 382.54 g/mol

Standard concentration: 10mg/mL

Appearance: Viscous, cloudy liquid

Pubchem CID: 44137686

CAS #: 1370003-76-1

The molecular structure of YK-11 derives directly from dihydrotestosterone (DHT), setting it apart from non-steroidal compounds in its class. This DHT-based backbone contributes to its unique binding properties and cellular interactions observed in laboratory studies. Researchers working with this substance will find the standard concentration of 10mg per milliliter provides optimal consistency for experimental protocols while maintaining solution stability.

The compound’s appearance as a viscous, cloudy liquid reflects its suspension in specialized solvents designed to ensure accuracy and stability. This form allows for precise measurement and administration in research settings, making it an ideal choice for scientists requiring exact quantity control in their studies.

Mechanism of Action

YK-11 functions through a dual mechanism as both a selective androgen receptor modulator and myostatin inhibitor. Research suggests this compound increases follistatin expression, which promotes muscle growth pathways in research models. YK-11 blocks myostatin, a protein that naturally limits muscle tissue development, while simultaneously stimulating follistatin production both systemically and locally.

Laboratory studies indicate potential for bone tissue engineering through osteoblast differentiation and activation of Akt protein phosphorylation for androgen-mediated bone development. The compound’s mechanisms operate through specific cellular pathways that researchers can analyze to understand tissue development processes.

Selective Androgen Receptor Modulation

The compound operates as a partial agonist at androgen receptors, demonstrating selective tissue targeting in research models. Unlike traditional androgens, YK-11 does not promote the complete N/C-terminal interaction required for full transcriptional activation, potentially explaining its tissue-selective effects observed in studies.

Myostatin Inhibition Pathway

Research demonstrates that YK-11 significantly upregulates follistatin expression, a glycoprotein that binds and neutralizes myostatin. This action removes natural limitations on cellular growth processes, making it valuable for researchers studying tissue development mechanisms. The compound’s ability to influence this pathway provides researchers with a unique tool for investigating cellular differentiation processes.

Animal studies have revealed that this dual action creates distinct cellular responses compared to other compounds in the same class, offering researchers opportunities to explore novel biological pathways and their potential applications in tissue engineering research.

Research Studies

Animal studies have shown YK-11’s protective effects against sepsis-induced muscle wasting and reduced mortality rates in septic mice through cytokine inflammation suppression. Research has demonstrated acceleration of osteoblast cell proliferation and mineralization when combined with DHT. YK-11 induces bone-specific markers like osteoprotegerin and osteocalcin, making it a promising candidate for bone tissue engineering research applications.

Muscle Tissue Research

The Kanno et al. (2013) study established significant findings regarding YK-11’s effects on C2C12 mouse myoblasts, demonstrating increased myogenic differentiation and hypertrophy through follistatin upregulation. These results provide researchers with valuable data for understanding cellular mechanisms and their potential applications in tissue research.

Research indicates that YK-11 treatment resulted in more pronounced effects compared to DHT alone, suggesting unique cellular interactions that researchers can explore further. The compound’s influence on protein synthesis pathways offers scientists opportunities to investigate fundamental biological processes.

Bone Development Studies

Yatsu et al. (2018) conducted comprehensive research demonstrating YK-11’s promotion of osteoblast proliferation and mineralization in MC3T3-E1 cells. The study revealed increased expression of bone-specific markers including osteoprotegerin and osteocalcin, providing researchers with evidence of the compound’s potential in bone tissue engineering applications.

These findings suggest that researchers investigating bone development mechanisms may find YK-11 a valuable tool for their studies. The compound’s ability to stimulate specific cellular markers makes it useful for scientists exploring tissue differentiation processes.

Protection Against Tissue Wasting

Animal studies have demonstrated protective effects against sepsis-induced tissue wasting, with researchers observing reduced mortality rates and decreased pro-inflammatory cytokine signaling. These results provide scientists with insights into potential anti-cachexia mechanisms and their applications in disease research models.

Storage and Safety

YK-11 liquid solution is provided in glass bottles with fixed droppers to prevent contamination and ensure accurate measurement. The product is suspended in USP grade PEG400 for stability and accuracy. Glass packaging prevents plasticizer leaching and maintains compound integrity. Store in a cool, dry place away from direct sunlight and keep tightly sealed when not in use for maximum stability.

Packaging Specifications

The use of blue glass bottles protects the compound from light degradation while preventing chemical interactions that could occur with plastic containers. Fixed droppers eliminate contamination risks and provide researchers with consistent measurement capabilities essential for reproducible results.

USP grade suspension ensures optimal solubility and stability, maintaining compound integrity throughout storage periods. This pharmaceutical-grade solvent system provides researchers with confidence in their experimental protocols and results.

Storage Protocols

Proper storage conditions prove crucial for maintaining compound stability and ensuring research accuracy. Researchers should maintain storage temperatures between 2-8°C when possible, though room temperature storage remains acceptable for short-term use.

The bottle should remain tightly sealed when not in use to prevent moisture absorption and maintain concentration consistency. These safety protocols ensure that researchers receive products meeting the highest grade standards throughout their intended use period.

Benefits of Buying from Loti Labs

Individual 30mL vials containing 300mg total YK-11 are competitively priced. Bulk discounts are available for larger research projects: 10% off for 5-9 vials, 15% off for 10-19 vials, and 20% off for orders of 20-49 vials. All YK-11 products from Loti Labs undergo rigorous quality control and are manufactured to the highest industry standards to ensure research accuracy and reproducibility.

Competitive Pricing Structure

Researchers will find Loti Labs offers transparent pricing that responds to varying research needs. The bulk discount structure provides significant savings for institutions conducting large-scale studies or long-term research projects. These pricing options make it easier for researchers to add quality compounds to their cart while managing research budgets effectively.

First order customers receive the same high-quality products and competitive pricing as established customers, ensuring all researchers have access to premium compounds regardless of their purchase history.

Quality Assurance Standards

Every batch undergoes comprehensive analysis to ensure researchers receive products meeting strict purity standards. The commitment to quality means researchers can trust their results and maintain consistency across multiple experiments.

The company’s focus on the highest quality manufacturing processes ensures that researchers receive products suitable for their most demanding experimental protocols. This attention to quality helps researchers achieve reliable, reproducible results in their studies.

Products from Loti Labs are for Research Use Only

All of the products sold by Loti Labs are intended as a research chemical only. This designation allows the use of this chemical strictly for in-vitro laboratory testing and experimentation. Human consumption or veterinary use is strictly forbidden. This product is not a dietary supplement, food or cosmetic and may not be misbranded, mislabeled or misused as such.

Research Designation Importance

The research-only designation ensures that customers understand the intended use and regulatory status of these compounds. This classification protects both researchers and suppliers by maintaining clear boundaries around approved uses.

Researchers should ensure their institutional review boards and safety committees approve all experimental protocols involving these compounds. Proper documentation and safety protocols remain essential for responsible research conduct.

Regulatory Compliance

The substance maintains its legal status through strict adherence to research-only guidelines. This designation ensures that researchers can obtain compounds for legitimate scientific purposes while maintaining compliance with regulatory requirements.

Institutions purchasing these products should maintain appropriate documentation and storage protocols consistent with research chemical handling guidelines. These measures help ensure continued access to quality compounds for scientific research.

Shipping Policy of Loti Labs

Loti Labs offers same day shipping for orders placed before 1pm EST Monday through Friday. Orders placed after 1pm EST or on weekends will be shipped the next business day.

Expedited Processing

The same-day shipping policy ensures researchers receive their compounds quickly, minimizing delays in research timelines. This rapid response helps scientists maintain project momentum and meet experimental deadlines.

Weekend orders receive priority processing on the following business day, ensuring minimal delays for time-sensitive research projects. Researchers can contact customer service for questions about shipping timeframes or special handling requirements.

Packaging and Handling

All products ship in protective packaging designed to maintain compound integrity during transit. Temperature-controlled shipping options are available for researchers requiring specific storage conditions.

Tracking information provides researchers with real-time updates on their shipments, allowing them to plan experimental protocols accordingly. This transparency helps researchers coordinate their work and ensure optimal compound handling upon receipt.

Satisfaction Guarantee

Loti Labs offers a 30 day satisfaction guarantee on all products purchased from us. Simply return any unopened products to us for a full refund of the purchase price of the unused products.

Customer Protection

The satisfaction guarantee demonstrates the company’s confidence in product quality while providing researchers with protection for their investment. This policy allows scientists to purchase with confidence, knowing they have recourse if products don’t meet their research needs.

Unopened products maintain full return eligibility, ensuring researchers can adjust their orders based on changing experimental requirements. This flexibility proves particularly valuable for research projects with evolving protocols or funding considerations.

Return Process

Customers can initiate returns by contacting customer service within the guarantee period. The straightforward return process minimizes administrative burden while ensuring researchers can focus on their scientific work.

Documentation requirements remain minimal, with the company prioritizing customer satisfaction and continued research relationships. This approach helps build trust between researchers and suppliers in the competitive research chemical market.

Third Party Testing of Every Batch

Every batch of products sold by Loti Labs undergoes rigorous third party testing by accredited American laboratories to ensure product purity and accuracy. All YK-11 products maintain a minimum 98% purity standard, and Certificates of Analysis are provided with each batch for verification.

Quality Control Protocols

Independent laboratory analysis ensures unbiased assessment of product quality and purity. These accredited facilities use advanced analytical techniques to verify compound identity and quantify purity levels.

The 98% minimum purity standard exceeds many industry benchmarks, providing researchers with confidence in their experimental results. This high standard helps ensure reproducibility and accuracy across different research applications.

Certificate of Analysis

Each batch includes documentation verifying compound specifications and purity levels. Researchers can review these certificates to confirm product quality and maintain proper laboratory documentation.

The certificates provide detailed analytical data that researchers can use to validate their experimental protocols and results. This transparency supports scientific rigor and helps researchers maintain compliance with institutional requirements.

Analytical Methods

Testing laboratories employ validated analytical methods including high-performance liquid chromatography (HPLC) and mass spectrometry to ensure accurate compound identification and quantification. These techniques provide researchers with confidence in product authenticity and purity.

Regular calibration and method validation ensure consistent testing standards across all batches. This systematic approach to quality control helps researchers achieve reliable results and maintain experimental consistency.

Conclusion

Research suggests YK-11 offers unique opportunities for scientists investigating cellular mechanisms, tissue development, and protein synthesis pathways. The compound’s dual action as both a selective androgen receptor modulator and myostatin inhibitor provides researchers with a valuable tool for exploring complex biological processes.

When researchers choose to buy YK-11 liquid from Loti Labs, they receive products manufactured to the highest quality standards with comprehensive quality assurance protocols. The combination of competitive pricing, rapid shipping, and satisfaction guarantees makes Loti Labs an optimal choice for research institutions and individual scientists.

For researchers seeking reliable access to high-grade compounds for their studies, Loti Labs provides the quality, consistency, and support necessary for successful scientific investigation. Contact our team to discuss your research needs and find the right products for your next breakthrough study.

References and Citations

1. Kanno Y, et al. (2013). Selective androgen receptor modulator, YK11, regulates myogenic differentiation of C2C12 myoblasts by follistatin expression. Biol Pharm Bull. 36(9):1460-5.
2. Yatsu T, et al. (2018). Selective androgen receptor modulator, YK11, up-regulates osteoblastic proliferation and differentiation in MC3T3-E1 cells. Biol Pharm Bull. 41(3):394-398.
3. Narayanan R, et al. (2018). Selective androgen receptor modulators in preclinical and clinical development. Nucl Receptor Res. 5:101320.
4. Lee SJ, Gharbi A, Shin JE, Jung ID, Park YM. (2021). Myostatin inhibitor YK11 as a preventative health supplement for bacterial sepsis. Biochem Biophys Res Commun. 543:1-7.
5. Yatsu T, Kusakabe T, Kato K, Inouye Y, Nemoto K, Kanno Y. (2018). Selective androgen receptor modulator, YK11, up-regulates osteoblastic proliferation and differentiation in MC3T3-E1 cells. Biol Pharm Bull. 41(3):394-398.
6. Biological & Pharmaceutical Bulletin. (2011). 34(3):318–23. PMID 21372378.

For more information on YK-11 please visit Wikipedia.

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Weight	0.1875 lbs
Appearance	Viscous cloudy liquid
Stability	Room Temperature out of direct sunlight
Molar Mass	430.541
CAS Number	1370003-76-1
Container	30ml Bottle
Molecular Formula	C25H34O6
Concentration	10mg per ML
Terms	This product is sold for research/laboratory usage only. No other uses are permited.