Pramipexole 2mg/ml (30ml)

Buy Pramipexole Liquid: Premium Dopamine Agonist Solutions

When researching dopaminergic pathways, you need precise, reliable compounds that meet laboratory standards. When you buy pramipexole liquid for your studies, the quality and consistency of the research compound matters. Pramipexole, a non-ergoline dopamine agonist, is a key tool for scientists studying dopamine receptor mechanisms, neurodegeneration models and cellular signaling pathways.

This guide covers the molecular properties, research applications and procurement options for pramipexole liquid formulations. Whether you’re doing in vitro receptor binding assays or exploring neuroprotective mechanisms in cellular models, understanding the specs and sourcing options for this research compound is critical for your experimental design.

Molecular Structure of Pramipexole

Pramipexole is a modern pharmaceutical chemistry masterpiece with the full chemical name (S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole. The molecular formula C10H17N3S reflects its unique structure while the molecular weight 211.33 g/mol makes it suitable for cellular uptake studies and receptor binding research.

Property	Value
Chemical Name	(S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole
Molecular Formula	C10H17N3S
Molecular Weight	211.33 g/mol
PubChem CID	119570
CAS Number	104632-26-0

The benzothiazole ring system is the backbone of pramipexole, with strategic substitutions that give it its pharmacological profile. The amino group at the 2-position and the propylamino group at the 6-position are responsible for receptor selectivity while the tetrahydro designation means reduction at specific ring positions. This flexibility makes it more water soluble than fully aromatic analogs, making liquid formulations perfect for research.

Understanding these molecular properties is crucial when you shop for pramipexole liquid as the compound’s properties affect its stability, solubility and experimental utility across different research protocols.

Mechanism of Action

Pramipexole is a non-ergoline dopamine agonist with high selectivity for the D2 subfamily of dopamine receptors, with a particular affinity for the D3 receptor subtype. This selectivity is different from other dopamine agonists and makes it a unique tool for dopaminergic research.

Research shows that the compound’s D3 receptor binding has advantages in experimental models. The D3 receptors are concentrated in limbic brain regions involved in mood regulation and motor control, making pramipexole a great tool to study these neural pathways. Unlike ergot-derived dopamine agonists, pramipexole’s non-ergoline structure eliminates the risk of fibrotic complications that can confound long-term research studies.

At the cellular level, pramipexole activation of D2/D3 receptors leads to adenylyl cyclase inhibition, modulating downstream signaling cascades relevant to neuroprotection and synaptic plasticity. Laboratory studies have shown that this mechanism is responsible for the compound’s efficacy in various experimental paradigms, from protecting neurons against oxidative stress to modulating neurotransmitter release patterns.

The compound’s receptor profile has made it very useful for researchers studying Parkinson disease models and restless legs syndrome mechanisms. Past customers sharing their research findings often mention pramipexole’s consistency in producing reproducible results across different experimental conditions, making it a reliable choice for investigators who need standardized dopaminergic modulation.

Research Studies and Applications

Extensive laboratory research has positioned pramipexole as a key compound for dopaminergic research. Scientists use this compound across multiple experimental paradigms, from basic receptor characterization to complex disease modeling studies. The compound’s versatility comes from its well-characterized pharmacology and consistent performance in different research settings.

In Vitro Research Applications

Cell culture studies often use pramipexole to study dopamine receptor signaling pathways. Researchers use the compound in receptor binding assays to determine affinity constants and functional responses at cloned human dopamine receptors. These studies have revealed important information on receptor subtype selectivity and downstream signaling mechanisms.

Neuronal culture experiments are another important application area. Scientists investigating neuroprotection mechanisms often expose cultured neurons to toxins like MPTP or 6-OHDA and then assess pramipexole’s protective effects. Research shows that the compound can reduce oxidative stress markers and inhibit apoptotic pathways in these experimental models.

In Vivo Research Models

Animal studies have characterized pramipexole’s effects in behavioral and biochemical research paradigms. Investigators use the compound to model dopaminergic dysfunction in rodent and primate systems, generating important data on motor function, cognitive processes and neurochemical changes.

Behavioral research has looked at how pramipexole affects locomotor activity, reward processing and motor coordination in laboratory animals. These studies provide fundamental data for understanding dopaminergic mechanisms and have informed more complex experimental designs.

The compound’s established safety profile in research settings has allowed for long-term studies of chronic dopaminergic modulation. Past customers often report successful implementation of long term treatment protocols, with product reviews highlighting the substance’s stability and consistency across extended experimental periods.

Storage and Safety Considerations

Proper storage protocols are crucial for maintaining pramipexole liquid integrity throughout research projects. The compound requires specific environmental conditions to preserve its chemical stability and biological activity. Laboratories must implement proper storage and handling procedures to get consistent results.

Storage Requirements

Store pramipexole liquid formulations at room temperature, between 20°C and 25°C. Protect the substance from direct light exposure as pramipexole is photosensitive and can degrade under intense light. Keep the original container with the cap tightly closed to prevent contamination and evaporation.

Commercial liquid formulations typically contain pramipexole at standardized concentrations of 0.5 mg/mL or 2 mg/mL depending on the research requirements. These concentrations eliminate the need for manual dissolution procedures, reducing preparation time and improving experimental consistency.

Laboratory Safety Protocols

Research use of pramipexole liquid requires standard laboratory safety measures. Personnel should wear appropriate personal protective equipment, including gloves and safety goggles, when handling the substance. While pramipexole is not a controlled substance, its biological activity at low concentrations requires careful handling procedures.

The compound’s pharmacology means accidental exposure can affect the central nervous system and cause drowsiness or coordination difficulties. Laboratories should have proper ventilation and spill response procedures in place.

Emergency procedures should include immediate contact with a healthcare professional if accidental exposure occurs. Laboratory personnel should be informed that pramipexole can interact with other medications and substances, and medical consultation is required in exposure incidents.

Why Buy from Loti Labs

Loti Labs offers research-grade pramipexole liquid formulations for laboratory use. The company’s focus on quality and consistency has made them a trusted supplier for institutional research programs and individual investigators. Several key benefits set their products apart in the research chemical market.

Standardized Formulations

Loti Labs offers pramipexole liquid at validated, standardized concentrations to ensure experimental reproducibility. This eliminates the variability associated with manual compound preparation and gives consistent results across different research protocols. Multiple concentration options are available to accommodate various experimental requirements from high-throughput screening assays to mechanistic studies.

The liquid form is particularly useful for cell culture applications and in vivo injection studies where solubility and dosage accuracy are critical. Researchers can add the compound directly to their experimental systems without additional preparation steps, streamlining laboratory workflows and reducing potential sources of error.

Quality Assurance

Every batch of pramipexole liquid is tested by a third-party using high-performance liquid chromatography (HPLC) to verify purity and concentration. This analytical method ensures batch-to-batch consistency, a critical factor for long-term studies and multi-site research collaborations. Certificates of analysis are available upon request to support institutional quality assurance requirements.

The company’s quality control goes beyond chemical analysis to include proper packaging and storage protocols. Temperature-controlled shipping maintains product integrity during transit and opaque containers protect against light-induced degradation. These quality measures contribute to the 96% customer satisfaction rating that reflects Loti Labs’ commitment to research excellence.

Ordering and Availability

Loti Labs has large stock levels to ensure product availability for time-sensitive research projects. The catalog includes 30 mL bottles for most laboratory applications with bulk ordering options for larger institutional programs. Custom concentration requests can often be accommodated for specialized research needs.

The ordering process is designed for efficiency with same-day shipping for orders placed before 1 PM EST, Monday through Friday. This fast turnaround helps researchers meet project timelines and reduce delays in critical experimental phases.

Research Use Only Compliance

All pramipexole liquid products from Loti Labs are for research use only, a regulatory classification that defines the intended use and limitations of the product. This classification is important for compliance with FDA guidelines and international regulations for laboratory chemicals. Understanding these restrictions is important for proper procurement and use.

Regulatory Framework

The research use only classification prohibits human use of these substances outside of approved clinical research settings. Products cannot be promoted or supplied for medical, food or cosmetic use and the labeling must state the intended research use. This regulatory framework protects both suppliers and researchers and ensures appropriate use of biological active compounds.

Laboratories purchasing pramipexole liquid must acknowledge these restrictions and implement controls to prevent unauthorized use. Institutional review boards and research oversight committees will require documentation of proper procurement and storage procedures as part of their approval process.

Laboratory Compliance

Research institutions must maintain detailed records of pramipexole procurement, storage and use to demonstrate compliance with research use only requirements. These records should include purchase documentation, storage logs and experimental protocols that clearly state the intended research use of the compound.

Personnel training is another critical compliance element. Laboratory staff must understand the limitations of research use only substances and the importance of preventing any use outside approved research context. Regular training updates will help maintain awareness of regulatory requirements and proper handling procedures.

Shipping and Customer Service

Loti Labs has developed comprehensive shipping and customer service policies to support research operations while maintaining product quality throughout the distribution process. These policies reflect the company’s understanding of research timelines and the critical importance of reliable chemical supply chains.

Shipping Protocols

The company’s shipping policy is focused on speed and product integrity. Orders received before 1 PM EST on business days are shipped the same day, orders received after 1 PM EST are shipped the next business day. All pramipexole liquid shipments are temperature controlled to prevent heat exposure during transit and preserve compound stability and potency.

Tracking information is provided for all shipments so researchers can track the delivery and plan their laboratory activities accordingly. The company’s shipping partners are selected based on their ability to maintain proper storage conditions and deliver products quickly to research facilities.

Customer Support

Loti Labs offers comprehensive customer support for technical questions, ordering inquiries and product information requests. The support team includes personnel with scientific background who can provide informed answers about product specifications and applications. This is particularly helpful for researchers who are new to pramipexole research or need clarification on storage and handling requirements.

Satisfaction Guarantee

The company stands behind its products with a 30-day satisfaction guarantee on unopened items. This policy reflects the company’s confidence in the product while providing researchers with recourse if the product does not meet their specifications. Returns must be unopened to maintain quality assurance throughout the supply chain so all distributed products meet the same high standards.96% customer satisfaction shows Loti Labs’ quality control and customer service is working. Past customers have reported positive experiences with product quality, shipping and technical support which has contributed to the company’s reputation in the research community.

Pricing and Value

When researchers buy pramipexole liquid they need to consider more than just the price. The total cost of research compounds includes purchase price, shipping, handling, storage requirements and potential costs of product variability or quality issues.

Loti Labs’ pricing reflects the quality control and customer service that supports research outcomes. While price is important, researchers should evaluate the total value proposition including product consistency, documentation and technical support.

Bulk ordering options provide cost savings for larger research programs and the standardized liquid formulations reduce project costs by eliminating preparation time and minimizing waste. These factors contribute to the overall value for research institutions looking for reliable pramipexole supplies.

Technical Specifications and Documentation

Researchers need detailed technical information to properly use pramipexole liquid in their protocols. Loti Labs provides documentation to support experimental design and regulatory compliance across different research settings.

Analytical Data

Each batch of pramipexole liquid includes HPLC analytical data. This confirms the compound’s identity, concentration and purity and is the documentation required for publication and regulatory submissions. The analytical methods used are pharmaceutical industry standards to ensure data quality and reproducibility.

Certificates of analysis are available upon request and include impurity profiles, moisture content and stability data. This is particularly important for institutional buyers who need to maintain quality assurance records for their research programs.

Stability

Long term stability studies provide guidance for storage and use timelines. Pramipexole liquid formulations are stable for extended periods when stored under recommended conditions with minimal degradation. This supports research projects that require consistent compound quality over months or years.

Temperature excursion studies help researchers understand the compound’s tolerance for brief storage deviations and provide practical guidance for laboratory operations. This is particularly useful for researchers in facilities with variable environmental controls or those conducting field studies.When deciding to buy pramipexole liquid for research you need to consider multiple factors from molecular specifications to supplier reliability. Pramipexole’s unique pharmacology as a non-ergoline dopamine agonist with D3 receptor selectivity makes it a valuable tool for dopaminergic research but only if sourced from suppliers who maintain quality standards.

Loti Labs addresses the needs of research institutions with standardized formulations, comprehensive quality control and customer service for scientific applications. The company’s research use only compliance ensures researchers can purchase and use pramipexole liquid with confidence in product quality and regulatory compliance.

For scientists investigating dopamine receptor mechanisms, neuroprotection pathways or disease models of conditions like Parkinson disease or restless legs, reliable access to high quality pramipexole liquid is crucial. The compound’s established efficacy in various experimental paradigms and excellent safety profile in research settings makes it a key tool to advance our understanding of dopaminergic neurobiology.

Whether your research is on basic receptor characterization, cellular protection mechanisms or complex behavioral studies, choosing the right supplier for pramipexole liquid can impact your experimental outcomes. Loti Labs’ approach to quality, service and compliance provides the foundation for successful research programs that advance scientific knowledge while maintaining laboratory standards.

Visit the Loti Labs website to see their catalog of research compounds and how their pramipexole liquid formulations can support your next breakthrough in dopaminergic research.

References

1. Parkinson’s Foundation. Dopamine Agonists (Pramipexole, Ropinirole). Available at: https://www.parkinsons.org.uk/information-and-support/dopamine-agonists-pramipexole-ropinirole
2. Bayview Pharmacy. Pramipexole Dihydrochloride 0.5 mg/ml Oral Suspension. Available at: https://www.bayviewrx.com/formulas/Pramipexole-Dihydrochloride-0-5-mg-ml-Oral-Suspension-Parkinson-s-Disease-Restless-Legs-Syndrome-Secondary-Parkinsonism-Tardive-Dyskinesia-Depression
3. Loti Labs. Buy Pramipexole Liquid for Research Use. Available at: https://www.lotilabs.com/pramipexole-liquid4.
4. PubChem. Pramipexole. Available at: https://pubchem.ncbi.nlm.nih.gov/compound/Pramipexole
5. CalPac Lab. Pramipexole Dihydrochloride 1g. Available at: https://www.calpaclab.com/pramipexole-dihydrochloride-1g-each/spc-tci-p2073-1g

For more information on Pramipexole please visit Wikipedia

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Weight	0.1875 lbs
Appearance	Viscous transparent liquid
Stability	Room Temperature out of direct sunlight
Molar Mass	211.33
CAS Number	104632-26-0
Container	30ml Bottle
Molecular Formula	C10H17N3S
Concentration	2mg per ML
Terms	This product is sold for research/laboratory usage only. No other uses are permited.