Oxytocin 2mg

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    Oxytocin peptide is a hormone made up of nine amino acids. It plays a critical role in social bonding, sexual reproduction, childbirth, and lactation. In this article, we will explore its structure, storage, effects on research subjects, and various applications in reproductive and behavioral studies. Additionally, we will discuss oxytocin’s potential, including its possible benefits and drawbacks for individuals with social relationship challenges.

    Key Takeaways

    Oxytocin is a nonapeptide synthesized by hypothalamic neurons, which are responsible for its pulsatile release, and plays vital roles in social behaviors, reproductive processes, and homeostasis.

    Proper storage of oxytocin, whether in lyophilized or reconstituted form, is crucial to maintain its stability and efficacy for research applications.

    Oxytocin significantly influences physiological processes such as uterine contractions during childbirth and milk ejection during lactation, and it also affects social behaviors and emotional responses.

    What is Oxytocin Peptide Hormone?

    Oxytocin is a nonapeptide, a small peptide hormone made up of nine amino acids: cysteine, tyrosine, isoleucine, glutamine, asparagine, cysteine, proline, leucine, and glycine. This specific sequence enables oxytocin to function effectively in the body.

    A notable feature of oxytocin’s structure is the disulfide bridge between two cysteine residues, which significantly enhances the molecule’s stability. This stability is vital for oxytocin to perform its various physiological roles effectively.

    Synthesized in the hypothalamus, oxytocin is stored in the posterior pituitary gland and released into the bloodstream as needed. This mechanism highlights the hormone’s role in maintaining homeostasis and responding to physiological triggers.

    Oxytocin is synthesized in specific brain regions and projects throughout the brain and spinal cord, affecting emotional functions and stress responses.

    Comprehending the chemical structure and synthesis of oxytocin is foundational for appreciating its diverse roles, from influencing social behaviors to facilitating reproductive processes.

    Oxytocin Receptor and Signaling

    The oxytocin receptor (OXTR) is a G-protein-coupled receptor that plays a pivotal role in mediating the effects of oxytocin. Widely distributed in the brain and peripheral tissues, including the uterus, mammary glands, and heart, OXTR is integral to various physiological processes.

    When oxytocin binds to OXTR, it triggers a signaling cascade involving the activation of G-proteins and the stimulation of various downstream effectors. This signaling is crucial for processes such as uterine contractions, milk letdown, and social behavior. Additionally, OXTR is involved in regulating stress response, anxiety, and fear behaviors, highlighting its broad impact on both physical and emotional health.

    Interestingly, OXTR can interact with other receptors, such as vasopressin receptors, to modulate its effects. The expression and function of OXTR are influenced by hormones, neurotransmitters, and environmental stimuli, making it a dynamic component of the body’s regulatory systems.

    Abnormalities in OXTR expression or function have been linked to various psychiatric and neurological disorders, including autism, schizophrenia, and postpartum depression. Understanding the complexities of OXTR signaling can provide valuable insights into these conditions and potential therapeutic approaches.

    How Oxytocin Affects Research Subjects

    Produced in the hypothalamus and released by the posterior pituitary gland, oxytocin is believed to play a crucial role in physiological and social behaviors, sparking keen interest among researchers.

    Research suggests that oxytocin, often referred to as the love hormone, may enhance feelings of happiness and social connection, improve impulse control, decrease appetite, and increase sensitivity to others’ emotions, highlighting its potential effects on social interactions.

    Environmental stimuli like skin-to-skin contact and cervical stimulation are thought to trigger oxytocin release, emphasizing its responsiveness to external cues and relevance in research. Additionally, studies suggest that oxytocin release is influenced by sexual stimulation, potentially playing a significant role in enhancing social bonding and emotional sensitivity during sexual activities.

    The following subsections delve deeper into oxytocin’s suggested effects on uterine contractions and lactation.

    Effects on Uterine Contractions

    Oxytocin is renowned in research for its role in stimulating uterine contractions during childbirth and promoting lactation. It is believed to enhance labor’s intensity and frequency through a positive feedback mechanism, ensuring efficient progression.

    Research indicates that oxytocin binds to specific oxytocin receptors on uterine smooth muscle, stimulating rhythmic contractions and facilitating childbirth. Understanding these mechanisms offers valuable insights for reproductive studies.

    Role in Lactation

    Research highlights oxytocin’s essential role in milk ejection during lactation. It is thought to trigger breast tissue contractions during breastfeeding, facilitating milk release in the “let-down reflex,” which is critical for effective breastfeeding.

    Post-delivery, oxytocin is suggested to speed up milk let-down, aiding breastfeeding. Understanding its role in lactation helps researchers explore applications for effective breastfeeding practices.

    Research Applications of Oxytocin

    Extensively studied for its role in physiological and social behaviors, oxytocin is significant for research. Research suggests its use in reproductive studies related to sexual activity, penile erection, ejaculation, and other processes is well-documented.

    Oxytocin also appears to play a crucial role in labor and delivery for pregnant animal models, helping to treat bleeding and affecting pregnancy outcomes.

    Research indicates oxytocin’s potential effects on social interactions and stress coping, highlighting its relevance in behavioral studies. This enhances understanding of reproductive health and social behavior, offering broader insights.

    Oxytocin in Reproductive Studies

    Research suggests oxytocin facilitates uterine contractions and milk ejection, regulating numerous reproduction-related processes and possibly influencing sexual activity, penile erection, ejaculation, and oxytocin levels milk ejection.

    Understanding these mechanisms enables researchers to explore oxytocin’s potential in reproductive health studies.

    Behavioral Studies Involving Oxytocin

    Research indicates oxytocin significantly influences social bonding and trust, promoting maternal bonding and nurturing behaviors. It may also foster closer relationships and reduce social anxiety symptoms, leading to more oxytocin.

    However, research suggests oxytocin’s effects can be complex. It may enhance the ability to read negative social cues, leading to overanalysis and hypersensitivity. Increased oxytocin in troubled relationships can sometimes strengthen connections to those relationships, underscoring the hormone’s nuanced impact.

    Therapeutic Applications of Oxytocin

    Oxytocin has garnered significant interest as a potential therapeutic agent for a range of conditions, including social anxiety disorder, autism spectrum disorder, and postpartum depression in animal models. Research has shown that oxytocin can improve social cognition and behavior in these models, offering hope for enhancing social interactions and quality of life.

    In addition to its effects on social behavior, oxytocin has been evaluated as a treatment for anxiety disorders, such as generalized anxiety disorder and post-traumatic stress disorder, in research settings. Its ability to modulate stress response and emotional processing underpins its therapeutic potential.

    Research suggests oxytocin has also been shown to increase trust, cooperation, and social bonding, which can be beneficial for individuals with psychiatric disorders in animal studies. Furthermore, it is being investigated as a treatment for addiction, including opioid and alcohol dependence, due to its influence on social and emotional behaviors.

    The therapeutic applications of oxytocin are being explored in various research trials, with promising results. As research progresses, oxytocin has the potential to revolutionize the treatment of psychiatric and neurological disorders, offering new avenues for improving mental health and social functioning in non-human models.

    Purchasing Oxytocin for Research

    Research suggests that oxytocin is available as a 2mg lyophilized powder specifically for research purposes, ensuring stability and quality for experimental use. Its CAS Number is 158861-67-7.

    Research indicates that oxytocin for research is not intended for human consumption. Researchers are advised to follow ethical considerations and regulations, sourcing oxytocin from reputable suppliers to maintain research integrity.

    Purchasing oxytocin requires finding products that meet stringent quality standards, ensuring the hormone retains its efficacy and stability for comprehensive research exploration.

    Summary

    Throughout this exploration, we have delved into the fascinating world of oxytocin, from its chemical structure to its critical roles in reproductive and behavioral research. Research suggests that understanding oxytocin’s storage and stability is essential for maintaining its quality and efficacy in research applications.

    Research highlights oxytocin’s effects on uterine contractions and lactation, underscoring its importance in reproductive health, while its role in social bonding and stress coping mechanisms underscores its relevance in behavioral studies. The potential applications of oxytocin in research are vast, offering insights into both physiological processes and social behaviors.

    As we look to the future, the possibilities for oxytocin research are boundless. By continuing to explore this peptide hormone’s multifaceted roles, researchers can uncover new avenues for understanding and potentially enhancing various aspects of health and social interaction.

    Frequently Asked Questions

    Where is Oxytocin stored and released in the posterior pituitary gland?

    Research indicates that oxytocin is stored and released from the posterior pituitary gland.

    What are some functions of Oxytocin in animal models?

    Research suggests that oxytocin regulates various reproduction-related processes in animal models, including sexual activity, penile erection, ejaculation, and milk ejection. Its influence on these functions underscores its significance in reproductive behavior.

    How does Oxytocin affect the smooth muscle of the uterus?

    Research suggests that oxytocin stimulates rhythmic contractions in the smooth muscle of the uterus by binding to its receptors. This action is crucial during labor, facilitating childbirth.

    What is the recommended storage condition for lyophilized Oxytocin?

    Research advises that lyophilized oxytocin should be stored at -20°C to ensure its stability and efficacy. This temperature prevents degradation and maintains the integrity of the compound.

    What is the CAS Number of Oxytocin?

    The CAS Number of Oxytocin is 158861-67-7.

    Citations

    1. Carter, C. S. (2014). Oxytocin pathways and the evolution of human behavior. Annual Review of Psychology, 65, 17-39. doi:10.1146/annurev-psych-010213-115110.
    2. Gimpl, G., & Fahrenholz, F. (2001). The oxytocin receptor system: Structure, function, and regulation. Physiological Reviews, 81(2), 629-683. doi:10.1152/physrev.2001.81.2.629.
    3. Young, L. J., & Barrett, C. E. (2015). Neuroscience. Can oxytocin treat autism? Science, 347(6224), 825-826. doi:10.1126/science.aaa8120.
    4. Lee, H. J., Macbeth, A. H., Pagani, J. H., & Young, W. S. (2009). Oxytocin: The great facilitator of life. Progress in Neurobiology, 88(2), 127-151. doi:10.1016/j.pneurobio.2009.04.001.
    5. MacDonald, K., & Feifel, D. (2013). Helping oxytocin deliver: considerations in the development of oxytocin-based therapeutics for brain disorders. Frontiers in Neuroscience, 7, 35. doi:10.3389/fnins.2013.00035.
    6. Insel, T. R. (2010). The challenge of translation in social neuroscience: A review of oxytocin, vasopressin, and affiliative behavior. Neuron, 65(6), 768-779. doi:10.1016/j.neuron.2010.03.005.
    7. Neumann, I. D., & Landgraf, R. (2012). Balance of brain oxytocin and vasopressin: Implications for anxiety, depression, and social behaviors. Trends in Neurosciences, 35(11), 649-659. doi:10.1016/j.tins.2012.08.004.
    8. Guastella, A. J., & Hickie, I. B. (2016). Oxytocin treatment, circuitry, and autism: A critical review of the literature placing oxytocin into the autism context. Biological Psychiatry, 79(3), 234-242. doi:10.1016/j.biopsych.2015.06.028.
    9. Uvnäs-Moberg, K., & Petersson, M. (2005). Oxytocin, a mediator of anti-stress, well-being, social interaction, growth, and healing. Zeitschrift für Psychosomatische Medizin und Psychotherapie, 51(1), 57-80. doi:10.13109/zptm.2005.51.1.57.
    10. Feldman, R. (2012). Oxytocin and social affiliation in humans. *

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    Anyone using products sold by LOTI LABS for any purpose other than research/laboratory use will be added to our no-sell list.

    For more information on Oxytocin please visit Wikipedia.


    Weight 0.0099 lbs
    Appearance Fine White Lyophilized Powder
    Residue Sequence CYIQNCPLG-NH2
    Solubility 100 µg/mL sterile diluent (distilled de-ionized water)
    Source Biosynthetic production
    Stability Lyophilized protein is to be stored at -20°C.
    It is recommended to divide the remaining reconstituted peptide into multiple vials
    so as to avoid a cycle of freezing and thawing. Reconstituted protein can be stored at 4°C.
    Molar Mass 1007.19 g/mol
    CAS Number 158861-67-7
    PubChem CID 439302
    Molecular Formula C43H66N12O12S2
    MG 2mg
    Terms This product is sold for research/laboratory usage only. No other uses are permited.
    Weight 0.05 lbs
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