GHRP-2 5mg

Buy GHRP-2 at Loti Labs: Premium Research Peptides for Scientific Investigation

Growth hormone releasing peptide 2 stands as a significant research tool for scientists investigating endocrine pathways and cellular signaling mechanisms. This synthetic peptide has garnered considerable attention in laboratory settings due to its potent activity as a ghrelin receptor agonist and its ability to stimulate gh release through well-characterized molecular pathways. When researchers buy ghrp 2 for experimental studies, they gain access to a compound that has demonstrated consistent results across diverse research applications, from growth hormone deficiency models to metabolic investigations.

Understanding the molecular structure, mechanism of action, and research applications of GHRP-2 enables scientists to design more effective experimental protocols while ensuring proper handling and storage procedures maintain peptide integrity throughout their studies.

Molecular Structure of GHRP-2

GHRP-2, classified as a growth hormone secretagogue and non glycosylated polypeptide chain, possesses a precisely defined molecular architecture that underlies its biological activity. The synthetic peptide follows the amino acid sequence H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2, incorporating both natural and modified amino acids that contribute to its stability and receptor binding properties.

Key Molecular Characteristics:

Property	Value
Molecular formula	C45H55N9O6
Molecular Weight	817.9 g/mol
Molecular mass	817.9 Da
PubChem CID	16133411
CAS Number	158861-67-7

The incorporation of D-amino acids at specific positions enhances the peptide’s resistance to enzymatic degradation, while the C-terminal amide group (Lys-NH2) contributes to its biological activity. This structural design represents one of the most potent members of the growth hormone releasing peptide family, demonstrating superior stability compared to naturally occurring hormone ghrelin.

 

Mechanism of Action

GHRP-2 functions through its interaction with growth hormone secretagogue receptor (GHS-R1α), primarily located within the pituitary gland and hypothalamus. Research suggests this binding activates G-protein coupled signaling pathways that trigger calcium influx through voltage-dependent channels, ultimately stimulating pulsatile growth hormone secretion from pituitary somatotrophs.

The peptide’s mechanism involves several interconnected cellular processes:

Primary Signaling Pathways:

• Ghrelin receptors activation leading to increased intracellular calcium
• Enhanced protein kinase C (PKC) pathway activity
• Modulation of cAMP-dependent signaling in certain experimental models
• Direct stimulation of gh releasing mechanisms independent of GHRH pathways

Studies in laboratory models demonstrate that GHRP-2 administration produces antinociceptive effects at the supraspinal level, suggesting additional receptor interactions beyond the primary growth hormone secretagogue receptor. The compound’s ability to stimulate gh release remains effective even in gh deficiency models, where traditional GHRH pathways show impaired function.

Research indicates that somatostatin can modulate GHRP-2’s effects, demonstrating the peptide’s integration within existing hormonal regulation systems. This interaction highlights the compound’s potential as an investigational drug for understanding complex endocrine feedback mechanisms.

Research Studies and Applications

Scientific investigations have explored GHRP-2’s effects across multiple research domains, providing valuable insights into growth hormone physiology and metabolic regulation. These studies demonstrate the peptide’s utility as a research tool for investigating various biological processes.

Growth Hormone Deficiency Research

Laboratory studies using lit/lit mice, which exhibit defective GHRH receptors, revealed significant findings about GHRP-2’s mechanism. Research suggests that administration of 10 mcg GHRP-2 produced gh release of 9.3 ± 1.5 ng/mL compared to 1.04 ± 1.15 ng/mL in control groups (p<0.001). These results demonstrate the peptide’s ability to bypass traditional GHRH-dependent pathways, making it valuable for studying alternative growth hormone regulatory mechanisms.

Metabolic and Growth Performance Studies

Animal research models have investigated GHRP-2’s effects on metabolism and growth performance. Studies in swine models indicate that peptide administration increased average daily gain by 22.35% while improving feed efficiency by 20.64%. These findings provide insights into the relationship between growth hormone signaling and metabolic efficiency, offering researchers tools to investigate enhance muscle growth mechanisms and energy utilization pathways.

Appetite and Food Intake Research

As a ghrelin receptor agonist, GHRP-2 has been utilized to study appetite regulation mechanisms. Research suggests the compound increases food intake by approximately 35-36% compared to placebo controls in experimental models. These studies help scientists understand the complex relationship between the hormone ghrelin, growth hormone pathways, and feeding behavior regulation.

Additional Research Applications

Scientists have explored GHRP-2’s potential in various other research areas:

• Cardiovascular protection studies examining myocardial signaling pathways
• Immune system modulation research investigating anti-inflammatory properties
• Muscle growth and tissue development investigations
• Insulin like growth factor pathway studies

Storage and Safety Guidelines

Proper storage protocols play a crucial role in maintaining GHRP-2’s integrity and biological activity throughout research studies. The lyophilized growth hormone releasing peptide requires specific environmental conditions to prevent degradation and ensure experimental reproducibility.

Storage Recommendations

Long Term Storage:

• Store lyophilized peptides desiccated below -18°C
• Maintain consistent temperature to prevent freeze thaw cycles
• Allow vials to equilibrate to room temperature before opening
• Protect from light and moisture exposure

Reconstituted Solutions:

• Stable for 3+ weeks when refrigerated at +4°C
• Extended stability of 3-4 months at -20°C
• Addition of carrier protein (0.1% HSA or BSA) recommended for extended storage
• Use aqueous solutions or other aqueous solutions as appropriate for experimental design

Handling Protocols

Research suggests that proper handling techniques significantly impact peptide stability and experimental outcomes. Scientists should avoid repeated freeze-thaw cycles, which can denature the synthetic peptides and reduce biological activity. When preparing stock solutions, researchers should consider the specific requirements of their experimental protocols and select appropriate solvents and concentrations.

The peptide demonstrates stability during standard shipping at room temperature, eliminating the need for special refrigeration during transport. This characteristic facilitates convenient procurement for research laboratories while maintaining product integrity.

Benefits of Buying from Loti Labs

Loti Labs provides researchers with high-quality GHRP-2 specifically designed for laboratory investigation and experimental studies. Our commitment to scientific excellence ensures that researchers receive peptides meeting the stringent requirements necessary for reproducible research outcomes.

Product Quality Standards

Purity Specifications:

• 98% purity verified through analytical testing
• 5mg vials containing lyophilized powder
• Glass vial packaging for optimal stability
• Ready for reconstitution in laboratory settings

Quality Assurance:

• Every batch undergoes rigorous third-party testing
• rp hplc analysis confirms identity and purity
• SDS-PAGE analysis provides additional verification
• Consistent quality standards across all production batches

Research Support Services

Our technical support team provides guidance on:

• Storage recommendations for optimal stability
• Experimental design considerations
• Product specifications and analytical data

Procurement Advantages

Researchers choosing Loti Labs benefit from:

• Competitive pricing structures
• Rapid order fulfillment and shipping
• Comprehensive product documentation
• Reliable supply chain for ongoing research projects

Regulatory Compliance and Research Use Designation

All products from Loti Labs, including GHRP-2, carry explicit designation for research use only. This classification ensures compliance with regulatory standards governing research chemicals and protects both suppliers and researchers from inappropriate use applications.

Research Use Only Guidelines

Permitted Applications:

• In-vitro laboratory testing and experimentation
• Cellular and molecular research studies
• Animal model investigations (where appropriate)
• Academic and commercial research projects

Prohibited Applications:

• Human therapeutic or diagnostic use
• Veterinary therapeutic applications
• Food or cosmetic product incorporation
• Any form of human consumption or administration

This designation reflects the current regulatory status of synthetic peptides used in research settings. Scientists must ensure their experimental protocols align with institutional guidelines and applicable regulations governing research chemical use.

Safety and Handling Considerations

Research facilities should implement appropriate safety protocols when working with synthetic peptides. While GHRP-2 demonstrates favorable stability characteristics, researchers should follow standard laboratory safety procedures, including proper personal protective equipment and waste disposal protocols.

The compound’s classification as an investigational drug substance requires careful documentation of use, storage, and disposal in accordance with institutional and regulatory requirements.

Shipping and Customer Service Policies

Loti Labs maintains efficient shipping protocols designed to meet the time-sensitive needs of research laboratories while ensuring product integrity during transport.

Shipping Schedule

Standard Shipping Timeline:

• Same-day shipping for orders placed before 1pm EST (Monday-Friday)
• Next business day shipping for orders placed after 1pm EST or weekends
• No refrigeration required during standard shipping periods
• Room temperature stability maintains peptide integrity during transport

Customer Satisfaction Guarantee

Our commitment to research excellence includes a comprehensive satisfaction guarantee:

• 30-day satisfaction guarantee on all purchases
• Full refund available for unopened products returned within guarantee period
• Quality assurance support for any product-related concerns
• Technical assistance for research protocol questions

Quality Control and Testing Procedures

Every batch of GHRP-2 undergoes comprehensive testing protocols to ensure consistent quality and purity standards that meet research requirements.

Analytical Testing Methods

Primary Analysis Techniques:

• High-Performance Liquid Chromatography (HPLC) for purity verification
• RP-HPLC analysis for detailed compositional analysis
• SDS-PAGE electrophoresis for protein integrity confirmation
• Mass spectrometry for molecular weight verification

Quality Benchmarks:

• Minimum 98% purity requirement for all batches
• Molecular identity confirmation through multiple analytical methods
• Stability testing under various storage conditions
• Contamination screening for common laboratory contaminants

Third-Party Verification

Independent laboratory testing provides additional quality assurance:

• Unbiased analytical verification of product specifications
• Confirmation of molecular formula and structure
• Validation of storage stability claims
• Documentation supporting research applications

This rigorous testing approach ensures that researchers receive peptides with consistent quality characteristics, enabling reproducible experimental results and reliable data generation.

Conclusion

GHRP-2 represents a valuable research tool for scientists investigating growth hormone pathways, metabolic regulation, and cellular signaling mechanisms. Its well-characterized molecular structure and mechanism of action provide researchers with a reliable compound for diverse experimental applications, from basic endocrine research to complex metabolic studies.

When researchers buy ghrp 2 from Loti Labs, they gain access to high-purity synthetic peptides backed by comprehensive quality assurance and technical support. Our commitment to research excellence ensures that scientists receive products meeting the stringent requirements necessary for successful experimental outcomes.

The combination of rigorous quality control, proper storage protocols, and regulatory compliance makes GHRP-2 from Loti Labs an optimal choice for research laboratories seeking reliable peptide sources. Whether investigating growth hormone deficiency models, metabolic pathways, or appetite regulation mechanisms, researchers can rely on consistent product quality and performance.

For research laboratories ready to advance their investigations into growth hormone physiology and related pathways, Loti Labs provides the quality, reliability, and support necessary for successful scientific discovery. Contact our technical support team to discuss your specific research requirements and discover how our premium peptides can enhance your experimental protocols.

All products are intended for research use only. Not for human or veterinary use.

References

1. Zeng, P., Li, S., Zheng, Y. H., Liu, F. Y., Wang, J. L., Zhang, D. L., & Wei, J. (2014). Ghrelin receptor agonist, GHRP-2, produces antinociceptive effects at the supraspinal level via the opioid receptor in mice. Peptides, 55, 103–109.
2. Phung, L. T., Inoue, H., Nou, V., Lee, H. G., Vega, R. A., Matsunaga, N., Hidaka, S., Kuwayama, H., & Hidari, H. (2000). The effects of growth hormone-releasing peptide-2 (GHRP-2) on the release of growth hormone and growth performance in swine. Domestic Animal Endocrinology, 18(3), 279–291.
3. Additional scientific literature on GHRP-2’s mechanism, storage, and research applications as cited throughout the article, including peer-reviewed journals and reputable peptide research sources.

Note: All references are provided for research use only and support the scientific context of GHRP-2 as a research peptide.

For more information on GHRP-2 peptide please visit Wikipedia.

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Weight	0.0099 lbs
Appearance	Lyophilized Powder
Amino Sequence	H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2
Solubility	100 µg/mL sterile diluent
Source	Biosynthetic production
Stability	Lyophilized protein is to be stored at -20°C. It is recommended to divide the remaining reconstituted peptide into multiple vials so as to avoid a cycle of freezing and thawing. Reconstituted protein can be stored at 4°C.
Molar Mass	817.9 g/mol
CAS Number	158861-67-7
PubChem	CID 6918245
Molecular Formula	C45H55N9O6
MG	5mg
Terms	This product is sold for research/laboratory usage only. No other uses are permited.

Weight	0.03125 lbs