Anastrozole 1mg/ml (30ml)

Buy Anastrozole Liquid at Loti Labs

Research into hormone-dependent pathways requires precise, reliable compounds that deliver consistent results across experimental protocols. When investigating aromatase inhibition and estrogen synthesis pathways, the quality and purity of research compounds directly impacts experimental outcomes and data integrity. For scientists examining these critical biological processes, anastrozole liquid represents a potent tool for selective enzyme inhibition studies.

The field of hormone research has revealed complex interactions between aromatase enzyme activity and various physiological processes. Studies have demonstrated that aromatase inhibitors play crucial roles in research models examining breast cancer progression, advanced breast cancer mechanisms, and metastatic breast cancer pathways. These investigations require compounds that maintain stability, demonstrate consistent potency, and provide reproducible results across diverse experimental conditions.

Understanding the molecular properties, mechanism of action, and proper handling requirements becomes essential when researchers seek to buy anastrozole liquid for their laboratory investigations. The compound’s effectiveness in research applications depends heavily on formulation quality, storage protocols, and the reliability of the supplier’s quality control measures.

Molecular Structure of Anastrozole

Anastrozole exhibits a specific chemical architecture that underlies its function as a selective aromatase inhibitor. The compound’s chemical name, 2,2’-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropiononitrile), reflects its complex triazole-containing structure that enables precise enzyme binding.

Property	Specification
Chemical Name	2,2’-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropiononitrile)
Molecular Formula	C17H19N5
Molecular Weight	293.4 g/mol
Concentration	1mg/mL
PubChem CID	2187
CAS Number	120511-73-1

The anastrozole chemical structure cas registry number 120511-73-1 provides researchers with precise identification for regulatory compliance and scientific referencing. This molecular configuration enables the compound to demonstrate high specificity for the aromatase enzyme while maintaining stability in various research formulations.

Research applications benefit from the standardized 1mg/mL concentration, which allows for accurate dilution calculations using the C1V1 = C2V2 formula. This precision proves essential when designing dose-response studies or establishing concentration gradients for in vitro anastrozole experiments. The clear solution form facilitates uniform distribution and enables researchers to mix evenly across experimental conditions.

Mechanism of Action

Anastrozole liquid functions as a potent, selective aromatase inhibitor with an IC50 of 15 nM against human placental aromatase. Research studies have demonstrated that the compound exhibits approximately 200 times greater potency than aminoglutethimide in laboratory investigations, establishing its effectiveness in experimental protocols examining enzyme inhibition.

The compound selectively inhibits human placental aromatase, the enzyme responsible for converting androgens to estrogens in various tissue types. This inhibition results in significant reductions in estradiol synthesis, with research models demonstrating 50-60% decreases in estrogen production. The mechanism involves competitive binding to the enzyme’s active site, effectively blocking the conversion pathway that produces estrogen from testosterone and androstenedione.

In research examining cancer cells, particularly those derived from breast tissue, anastrozole demonstrates effectiveness in models where estrogen-dependent growth pathways are investigated. Clinical trials have utilized this compound to study hormone receptor-positive conditions, though laboratory researchers focus on understanding the underlying biochemical mechanisms through controlled experimental systems.

The compound’s selectivity becomes particularly relevant when studying human placental microsomes, where aromatase activity plays critical roles in steroid hormone synthesis. Research suggests that anastrozole’s binding affinity and residence time on the enzyme contribute to its sustained inhibitory effects, making it valuable for studies requiring prolonged enzyme suppression.

Studies involving male pigtailed monkeys have provided insights into the compound’s effects on aromatase activity across different tissue types. These investigations have revealed tissue-specific responses to aromatase inhibition, contributing to our understanding of estrogen synthesis regulation in various biological contexts.

Research Studies

Research formulations of anastrozole liquid are optimized for laboratory applications with specific vehicle compositions designed to enhance solubility and biocompatibility. The formulation method varies depending on whether studies involve in vitro or in vivo experimental models, with each approach requiring careful consideration of vehicle effects on experimental outcomes.

This simplified composition reduces potential toxicity concerns while maintaining adequate bioavailability for research purposes. The corn oil vehicle facilitates absorption and provides a stable matrix for compound delivery in experimental animals.

These specialized formulations enable precise administration in research models examining hormone-dependent pathways. Studies investigating apoptosis mechanisms in estrogen-sensitive cell lines benefit from the controlled delivery that these formulations provide. Research into arthritis models has also utilized anastrozole formulations to examine the role of estrogen in inflammatory processes.

The choice of formulation affects compound stability and biological activity, making it essential for researchers to select appropriate vehicle compositions based on their specific experimental requirements. Some studies may require modifications to standard formulations to accommodate particular experimental conditions or analytical methods.

Storage and Safety

Anastrozole liquid requires specific storage conditions to maintain stability and efficacy throughout research timelines. Proper handling protocols ensure compound integrity and support reproducible experimental results across multiple studies.

Storage Requirements

Research stock solutions should be stored according to the following specifications:

Storage Condition	Duration	Temperature
Long-term storage	Up to 2 years	-80°C
Medium-term storage	Up to 1 year	-20°C
Working solutions	As needed	4°C (short-term)

Researchers must avoid repeated freeze-thaw cycles that may compromise compound integrity and potency. The solution requires protection from light and moisture unless otherwise specified in experimental protocols. Proper labeling with storage dates and concentration information helps maintain laboratory organization and safety standards.

Research Observations

Safety considerations include potential effects observed in research models during experimental protocols. Studies have documented various physiological responses in animal models, including thermoregulatory changes that may affect experimental conditions. Joint symptoms have been noted in some research animals, particularly in long-term studies examining chronic aromatase inhibition.

Research models have demonstrated mood changes associated with reduced estrogen synthesis, providing insights into hormone-behavior relationships. Some studies have reported observations of hot flashes in experimental subjects, reflecting the compound’s effectiveness in reducing estrogen production.

More significant research observations include effects on bone mineral density in animal models subjected to prolonged treatment protocols. Studies examining osteoporosis development have utilized anastrozole to investigate the relationship between estrogen deficiency and bone metabolism. Research into fractures and bone strength has provided valuable data on hormone-bone interactions.

Investigations into heart disease risk factors have examined how aromatase inhibition affects cardiovascular parameters in research models. These studies contribute to understanding the complex relationships between hormone status and cardiovascular health.

Researchers should monitor experimental subjects for signs of weakness or other physiological changes that might indicate compound effects. Some studies have noted nausea or vomiting in research animals, though these observations vary depending on the specific experimental protocol and species studied.

Additional considerations include potential skin reactions at injection sites in research animals, though these effects typically remain localized and resolve without intervention. Headache-like behaviors have been observed in some primate studies, suggesting potential central nervous system effects of estrogen suppression.

Benefits of Buying from Loti Labs

Loti Labs provides research-grade anastrozole liquid with precise 1mg/mL concentration, allowing for accurate dilution using standard laboratory calculations for experimental protocols. The formulation maintains stability throughout research timelines when stored according to recommended conditions, ensuring consistent results across extended study periods.

Quality Control Standards

Each batch undergoes rigorous quality control measures to ensure consistency in research applications. The company maintains 99.99% HPLC-confirmed purity standards, providing researchers with confidence in compound quality and potency. This level of purity proves essential for studies where even minor impurities could affect experimental outcomes.

Third-party testing protocols verify compound identity and purity using high-performance liquid chromatography (HPLC), a gold standard analytical method in pharmaceutical research. Certificates of analysis accompany each product shipment, providing detailed documentation of quality parameters and test results.

Delivery and Logistics

Efficient delivery systems support research timelines and experimental scheduling. The company’s logistics network ensures that temperature-sensitive compounds maintain integrity during transport, utilizing appropriate packaging and shipping methods for research chemicals.

Researchers can adjust their ordering schedules to accommodate experimental timelines, with flexible delivery options that support both routine laboratory operations and urgent research needs. The reliable supply chain helps prevent experimental delays due to compound availability issues.

Products from Loti Labs are for Research Use Only

All products sold by Loti Labs are intended as research chemicals only. This designation allows the use of these compounds strictly for in-vitro laboratory testing and experimentation. Human use is strictly forbidden, and these products are not intended for human or veterinary applications.

This product is not a prescription substance, food, or cosmetic and may not be misbranded, mislabeled, or misused as such. The research use only designation ensures compliance with regulatory requirements and protects against inappropriate applications.

Researchers must understand that these compounds are intended exclusively for laboratory investigations examining biological mechanisms, cellular processes, and molecular pathways. Studies involving these compounds should follow established research protocols and institutional safety guidelines.

The distinction between research chemicals and therapeutic agents remains critical for regulatory compliance and ethical research practices. Pharmacist consultation or medical supervision is not applicable to research chemical applications, as these compounds serve different purposes than prescription substances used in clinical settings.

Shipping Policy of Loti Labs

Loti Labs offers same-day shipping for orders placed before 1pm EST Monday through Friday. Orders placed after 1pm EST or on weekends will be shipped the next business day. This expedited shipping policy supports research timelines and helps prevent experimental delays.

Temperature-controlled shipping ensures compound stability during transport, utilizing appropriate packaging materials and delivery methods for research chemicals. Tracking information provides researchers with real-time updates on shipment status and expected delivery times.

Satisfaction Guarantee

Loti Labs offers a 30-day satisfaction guarantee on all products purchased from the company. Researchers may return any unopened products for a full refund of the purchase price, reflecting the company’s confidence in product quality and customer service standards.

This guarantee provides researchers with flexibility when planning experiments and ordering compounds. The policy supports research budgets by reducing risks associated with product quality concerns or changing experimental requirements.

Third Party Testing of Every Batch

Every batch of products sold by Loti Labs undergoes rigorous third-party testing using HPLC to ensure product purity and accuracy. Certificates of analysis confirm 99.99% purity standards and are provided with each purchase, allowing researchers to proceed with confidence in their experimental protocols.

Independent testing laboratories perform these analyses using validated analytical methods and calibrated instrumentation. The testing protocols examine both compound identity and purity, ensuring that researchers receive materials that meet specifications for their intended applications.

Quality assurance measures include stability testing under various storage conditions, helping researchers understand how to maintain compound integrity throughout their experimental timelines. These comprehensive testing protocols support reproducible research outcomes and scientific rigor.

Research Applications and Considerations

When researchers buy anastrozole liquid, they gain access to a compound that has demonstrated effectiveness across numerous research applications. Studies examining hormone-dependent cellular processes benefit from the compound’s selective action and predictable dose-response relationships.

Research into breast cancer mechanisms utilizes anastrozole to investigate how aromatase inhibition affects tumor cell growth and survival pathways. These studies contribute to understanding the complex relationships between hormone synthesis and cellular proliferation in cancer models.

Investigations of advanced breast cancer progression examine how prolonged aromatase inhibition influences metastatic processes and cellular invasion mechanisms. Research models using anastrozole help scientists understand the molecular events underlying disease progression and treatment response.

Studies of metastatic breast cancer utilize the compound to examine how estrogen synthesis affects cellular migration and tissue invasion. These investigations provide insights into hormone-dependent aspects of cancer biology and potential therapeutic targets.

Research examining the relationship between aromatase inhibitors and bone metabolism has revealed important connections between estrogen synthesis and skeletal health. Studies investigating osteoporosis development in experimental models demonstrate how hormone suppression affects bone formation and resorption processes.

Comparative studies with other compounds like tamoxifen provide researchers with valuable data on different approaches to hormone pathway modulation. These investigations help scientists understand the relative effectiveness of various research tools for examining estrogen-dependent processes.

Experimental Considerations

Researchers should consider several factors when incorporating anastrozole liquid into their experimental protocols. The compound’s potency requires careful attention to concentration calculations and dose preparation to ensure appropriate experimental conditions.

Studies examining enzyme inhibition kinetics benefit from the compound’s well-characterized binding properties and competitive inhibition mechanism. Research investigating cellular response pathways can utilize anastrozole’s selective action to isolate estrogen-dependent effects from other hormonal influences.

The compound’s stability under various experimental conditions allows for extended studies examining chronic effects of aromatase inhibition. Research protocols can accommodate both acute and chronic exposure models, depending on the specific research questions being investigated.

Experimental design should account for potential interactions between anastrozole and other research compounds or cellular culture conditions. Some studies may require vehicle controls or comparative analyses with related compounds to isolate specific effects.

Researchers conducting studies in postmenopausal women models or examining age-related hormonal changes may find anastrozole particularly useful for investigating estrogen synthesis regulation across different life stages. These applications contribute to understanding how hormone production changes with aging and disease states.

Conclusion

Research into hormone-dependent biological processes requires access to high-quality compounds that deliver consistent, reproducible results. When scientists buy anastrozole liquid from Loti Labs, they obtain a research tool that combines molecular precision with rigorous quality standards, supporting investigations across diverse experimental applications.

The compound’s well-characterized mechanism of action, optimal formulation properties, and comprehensive quality control measures make it suitable for studies examining aromatase inhibition and estrogen synthesis pathways. From cellular investigations to complex animal models, anastrozole liquid provides researchers with the reliability needed for scientific advancement.

Loti Labs’ commitment to quality, supported by third-party testing and extensive scientific validation, ensures that researchers receive compounds meeting the highest purity standards. The company’s research-only designation maintains regulatory compliance while supporting legitimate scientific investigations.

For research teams examining hormone-dependent processes, cancer cell biology, or endocrine system function, anastrozole liquid represents a valuable addition to their experimental toolkit. The combination of molecular specificity, formulation stability, and quality assurance provides the foundation for meaningful scientific discoveries.

Consider evaluating anastrozole liquid for your next research protocol examining aromatase inhibition or estrogen-dependent cellular processes. Review the detailed specifications, storage requirements, and application guidelines to determine how this compound might support your laboratory’s research objectives.

References

1. Dukes M, et al. The preclinical pharmacology of “Arimidex” (anastrozole; ZD1033)—a potent, selective aromatase inhibitor. J Steroid Biochem Mol Biol. 1996 Jul;58(4):439-45.
2. Kelly CM, Buzdar AU. Anastrozole. Expert Opin Drug Saf. 2010 Nov;9(6):995-1003.
3. Hong Y, Chen S. Aromatase inhibitors: structural features and biochemical characterization. Ann N Y Acad Sci. 2006 Nov;1089:237-51.
4. McCloskey E. Effects of third-generation aromatase inhibitors on bone. Eur J Cancer. 2006 May;42(8):1044-51.
5. Xanthopoulos JM, Romano AE, Majumdar SK. Response of Mouse Breast Cancer Cells to Anastrozole, Tamoxifen, and the Combination. J Biomed Biotechnol. 2005;2005(1):10-19.
6. Bayview Pharmacy. Anastrozole 1 mg/ml Gastric Tube Liquid – Customized Care. Available at: https://www.bayviewrx.com/formulas/Anastrozole-1-mg-ml-Gastric-Tube-Liquid-Breast-Cancer-Ovarian-Cancer-Endometrial-Cancer-Infertility-McCune-Albright-Syndrome
7. MedChemExpress. Anastrozole (ZD1033) | Aromatase Inhibitor. Available at: https://www.medchemexpress.com/Anastrozole.html

For more information on Anastrozole please visit WikiGenes.

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Weight	0.1875 lbs
Appearance	Viscous transparent liquid
Stability	Room Temperature out of direct sunlight
Molar Mass	293.37
CAS Number	120511-73-1
Container	30ml Bottle
Molecular Formula	C17H19N5
MG	1mg
Terms	This product is sold for research/laboratory usage only. No other uses are permited.

 

Weight	0.156 lbs