T3 (Liothyronine) 100mcg/ml (30ml)
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This product is intended as a research chemical only. This designation allows the use of this chemical strictly for in-vitro laboratory testing and experimentation. Human or veterinary use is strictly forbidden. This product is not a drug, food or cosmetic and may not be misbranded, mislabeled or misused as such.
Buy T3 Liothyronine at Loti Labs: Pharmaceutical-Grade Thyroid Hormone Solutions
When healthcare providers need to buy T3 liothyronine for their patients with hypothyroidism or other thyroid gland disorders, it’s crucial to choose a reliable, accredited source. T3 liothyronine is a synthetic form of thyroid hormone that requires precise formulation, proper storage and strict prescription control to ensure patient safety and efficacy.
Loti Labs is a PCAB-accredited compounding pharmacy specializing in customized thyroid hormone formulations, offering healthcare providers and their patients pharmaceutical-grade T3 liothyronine with quality control and personalized dosing options. Understanding the molecular characteristics, clinical applications and safety requirements of this thyroid hormone helps in making informed treatment decisions.
Molecular Structure of T3 Liothyronine
T3 liothyronine has a defined molecular structure that determines its biological activity and therapeutic potential. The compound has the following specifications:
| Property | Value |
|---|---|
| Amino Sequence | Tyrosine-based structure with three iodine atoms at specific positions |
| Molecular Formula | C15H12I3NO4 |
| Molecular Weight | 650.97 g/mol |
| PubChem CID | 5920 |
| CAS Number | 55-06-1 |
The three iodine atoms—two on the inner benzene ring at positions 3 and 5, and one on the outer ring at position 3’—create the unique configuration that allows T3 to bind to thyroid hormone receptors with high affinity. This structure is what differentiates liothyronine from other thyroid hormones like levothyroxine and results in its rapid onset and potent metabolic effects.
Mechanism of Action
T3 liothyronine is a synthetic form of the natural thyroid hormone triiodothyronine and regulates metabolism throughout the body. When introduced into the system, this compound binds to thyroid hormone receptors (TRα and TRβ) in the cell nucleus, influencing protein synthesis and oxygen consumption in cells.
The mechanism involves several steps:
- Cellular uptake: T3 enters the target cells and translocates to the nucleus
- Receptor binding: High-affinity binding to nuclear thyroid hormone receptors
- DNA interaction: The receptor-hormone complex interacts with thyroid response elements
- Gene transcription: Modulation of genes responsible for basal metabolic rate regulationThis affects basal metabolic rate, cardiac function and various developmental processes so it’s essential for primary hypothyroidism and other thyroid status disorders. Unlike levothyroxine, T3 has faster onset and shorter half-life resulting in faster but shorter acting effects which is very useful in acute situations like myxedema coma.
Research Studies
Clinical studies show that T3 liothyronine normalizes thyroid function in hypothyroid patients. Research indicates regular monitoring is necessary, with lab results to be checked through serum TSH, free T3 and free T4 every 6-12 weeks initially, then every 6 months once stabilized.
Research Observation Requirements
Research studies show that special population including elderly, pregnant animal models and those with cardiac conditions in laboratory settings require careful consideration and more frequent observation protocols. Research findings indicate that endocrinologist oversight is beneficial for such research subjects receiving combination T4/T3 compound protocols as these research models require more observation including:
- Atrial rhythm irregularities in research settings
- Coronary artery responses in laboratory conditions
- Bone mineral density changes with extended research protocols
- Pituitary gland responses requiring protocol adjustments
Combination Compound Research
Clinical studies show that most research subjects respond to levothyroxine monotherapy in laboratory settings. However, a subset of research models do not respond despite normal lab results, so some researchers recommend combination compound protocols. Research subject response varies, some lab results show improved cognitive markers and energy measurements but objective data is inconclusive in research environments.
Research suggests potential use in laboratory settings but specific outcomes cannot be guaranteed
Special Research Considerations
Research indicates that compound protocols should never be used for weight loss in research subjects with normal thyroid status, as misuse can cause serious cardiac observations in laboratory settings. Research studies show that using thyroid compounds for weight research in euthyroid research models increases incidence of adverse outcomes including rapid or irregular rhythm patterns and bone density changes in controlled environments.
These substances are not for human consumption and are intended for research use only
Storage and Research Safety
Proper storage protocols ensures T3 liothyronine remains potent and effective in research settings. The compound should be stored in sealed containers at -20°C to -80°C depending on formulation requirements for research use. Standard immediate release formulations require controlled room temperature storage between 15°C to 30°C (59°F to 86°F) in research facilities, while research grade preparations may require ultra-low temperature storage protocols.
Research Storage Guidelines
- Keep away from moisture and light in laboratory conditions
- Follow storage instructions from your research supplier
- Maintain consistent temperature in research environments
- Use sealed, appropriate containers for formulation type in laboratory settings
All compounds are for research use only and require laboratory oversight
Loti Labs Research Advantages
Loti Labs provides pharmaceutical-grade T3 liothyronine for research with several advantages that sets the research facility apart from standard suppliers:
Research Compound Delivery Systems
Research shows that specialized delivery systems can improve compound stability and research outcomes in controlled laboratory environments. The facility has strict quality control protocols to ensure consistent research-grade compounds that meet laboratory standards for scientific research.
Combination Research Protocols
When scientifically justified, the laboratory supplies combination T4/T3 compound preparations so researchers can use evidence-based methods for studies where levothyroxine monotherapy is not effective in research settings. These specialized formulations require collaboration between laboratory personnel and research scientists to optimize experimental protocols based on individual study parameters.
Research shows combination protocols may have advantages in specific research applications but outcomes vary greatly based on experimental conditions and research model.
Research suggests potential use in laboratory settings but specific outcomes cannot be guaranteed. All compounds are for research use only and require laboratory oversight
These substances are not for human consumption and are intended for research use only
Regulatory Compliance
All research compounds follow federal and state regulations for research thyroid compounds. The facility has verification processes to ensure dispensing only occurs with valid research authorization, minimizing diversion and proper scientific oversight for every research protocol.
Research facilities like Loti Labs understand the importance of research use only and provides high quality compounds for legitimate scientific research. The laboratory’s compliance ensures researchers can focus on their research while having confidence in compound quality and legal compliance.
References
- Vanderpump, M. “Liothyronine (L-T3) in hypothyroidism.” The Endocrinologist, Fall 2017. Link
- Mayo Clinic. “Liothyronine (oral) – Description, dosage, and precautions.” Link
- MedChemExpress. “Liothyronine sodium (Triiodothyronine sodium) datasheet and research overview.” Link
- CareFirst Specialty Pharmacy. “Liothyronine (T3) Compounded medication information.” Link
- Amazon Pharmacy. “Liothyronine Generic for Cytomel Oral Tablet instructions.” Link
- British Thyroid Association. “Statement on combination L-T4/L-T3 therapy in hypothyroidism.” Link
For more information on Liothyronine visit Wikipedia.
| Weight | 0.1875 lbs |
| Appearance | Viscous transparent liquid |
| Stability | Room Temperature out of direct sunlight |
| Molar Mass | 273.3 |
| CAS Number | 1596-67-4 |
| Container | 30ml Bottle |
| Molecular Formula | C15H15NO4 |
| Concentration | 100mcg per ML |
| Terms | This product is sold for research/laboratory usage only. No other uses are permited. |
| Weight | 0.156 lbs |
|---|
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