SR9009 Capsules (10mg/capsule, 30 capsules)

Buy SR9009 Capsules at Loti Labs

Research into circadian rhythm regulation has uncovered some amazing molecular mechanisms that govern metabolic processes across different species. Among the compounds developed to study these pathways, SR9009 is a key research tool originally synthesized at the Scripps Research Institute under the guidance of Professor Thomas Burris. This synthetic Rev-ErbA agonist is a must have for research scientists to study the intricate relationships between circadian rhythms, metabolism and cellular energy production.

For research scientists looking to buy SR9009 capsules, understanding the compound’s molecular properties, mechanism of action and handling protocols is crucial for successful laboratory research use. Research shows this compound gives insights into metabolic regulation, so it’s an important addition to studies on glucose metabolism, lipid storage mechanisms and mitochondrial function in muscle cells.

Molecular Structure of SR9009

Chemical Name: SR9009 (Stenabolic)

Molecular Formula: C20H24ClN3O4S

Molecular Weight: 437.94 g/mol

PubChem CID: 57381769

CAS #: 1379686-30-2

The molecular structure of SR9009 is a pyrrolidine carboxylic acid derivative with chlorophenyl and nitrothienyl methyl amino moieties. Research shows this unique configuration allows for binding to Rev-ErbA receptors and the compound has high lipophilicity (XLogP3-AA value of 4.4) which enhances cellular membrane permeability. The structure has 6 hydrogen bond acceptors and 0 hydrogen bond donors, which affects its pharmacokinetic properties and receptor binding affinity.

These molecular properties allow SR9009 to cross cellular membranes efficiently, so researchers can study its effects on different tissue types including liver, muscle and fat storage sites. The compound is stable at room temperature so it’s suitable for long term laboratory research use, but proper storage protocols are still necessary to maintain its integrity.

Mechanism of Action

SR9009 is a synthetic Rev-ErbA agonist that selectively targets REV-ERBα and REV-ERBβ nuclear receptors. Research shows the compound activates these receptors in liver, muscle and fat tissue to regulate gene expression related to circadian rhythms and metabolic processes. Studies show SR9009 increases mitochondrial biogenesis, increases cellular energy production and influences lipid and glucose metabolism pathways to maintain metabolic balance.The compound has high selectivity with half maximal inhibitory concentrations of 670 nM for REV-ERBα and 800 nM for REV-ERBβ, so it has good binding affinity. Research shows activation of Rev Erb protein pathways suppresses genes involved in glucose and lipid synthesis and increases endurance through enhanced mitochondrial function.

Lab studies show SR9009’s mechanism goes beyond simple receptor activation. Research shows the compound influences gene transcription related to inflammation and cellular energy expenditure and some studies show Rev Erb independent actions. This complexity makes SR 9009 very useful for researchers to study how the body regulates metabolism through multiple pathways.

The Rev ErbA agonist property allows researchers to study how circadian rhythm disruption affects metabolic diseases. Research shows the compound’s activation of Rev Erb receptors affects the production of proteins involved in fat burning processes but researchers note the short half life requires careful consideration in experimental design.

Research Studies

Animal studies since 2012 have shown SR9009 to increase mitochondrial production in muscle cells, significant fat loss, improve endurance and reduce inflammation. Research shows potential applications for obesity, type II diabetes and cholesterol disorders. Current research is focused on circadian rhythm regulation, metabolic disease prevention and cardiovascular health benefits.

Research Area	Observed Effects	Study Duration
Mitochondrial Function	Increased biogenesis in muscle tissue	Multiple weeks
Lipid Metabolism	Reduced fat storage without food intake changes	Extended studies
Glucose Metabolism	Improved insulin sensitivity markers	Ongoing research
Inflammation	Decreased pro inflammatory cytokines	Various timeframes

Research shows SR9009 affects the body’s metabolism through multiple mechanisms. Studies show the compound’s effects on fat burning processes are independent of food intake changes, so it’s a direct metabolic effect. Lab research has shown significant fat loss in animal models and researchers have seen improvement in the body’s ability to use stored energy sources.

Fitness enthusiasts and bodybuilders are interested in these research findings but all current data is from lab research only. The compound is useful for researchers to study weight loss mechanisms so it’s valuable for researchers to study metabolic disease prevention. Studies show optimal results in lab settings depend on proper experimental protocols and consistent compound quality.Recent research has gone beyond basic metabolism studies. Research shows SR9009 may have implications for cardiovascular health with studies looking at its effects on exercise capacity and stamina in controlled lab settings. Research shows the compound affects genes involved in muscle mass but more research is needed to understand the full implications.

Storage and Safety

SR9009 should be stored in a cool, dry place away from direct sunlight. The compound is stable at room temperature but should be stored in its original container with the lid tightly sealed. For lab safety, researchers should use proper PPE and follow institutional guidelines when handling this research compound.

Proper storage protocols ensure the compound remains intact throughout extended research periods. Lab research shows exposure to moisture, heat or direct sunlight can affect the compound’s stability and research outcomes. Researchers should note that proper storage contributes to consistent experimental results and data collection.

Lab safety protocols include:

• Use of proper PPE
• Proper ventilation in lab areas
• Adherence to institutional safety guidelines
• Storage away from unauthorized access
• Regular inventory tracking for research purposes

The compound is stable for various research applications but researchers should contact suppliers for specific storage recommendations based on their lab conditions. Quality maintenance depends on following established protocols throughout the research process.

Why Buy from Loti Labs

Buying SR9009 from Loti Labs ensures you get a high purity research compound from a reputable supplier with a proven track record. Our high quality products come with detailed specs, storage info and consistent capsule strengths. We maintain lab conditions throughout our handling procedures to ensure the highest quality standards for your research needs.

Loti Labs offers several advantages for researchers looking for reliable compound sources:

• Third-party testing verification: Every batch is HPLC tested
• Consistent quality standards: Maintained throughout production and storage
• Product specs: Complete molecular and handling information
• Professional packaging: Secure containers with proper labeling
• Research compliance: All products for lab research use only

Our quality control ensures researchers get compounds that meet their experimental requirements. The consistency of our products supports reliable research outcomes and data collection across multiple studies. Researchers can expect the same quality standards whether ordering single batches or multiple supplies for extended research projects.

Customer support includes technical support for storage questions and research applications. We understand the importance of compound integrity for successful lab research and maintain stock levels to support ongoing research projects without interruption.## Loti Labs Products are for Research Use Only

All products sold by Loti Labs are research chemical only. This means the use of this chemical is strictly for in-vitro laboratory testing and experimentation. Human consumption is strictly forbidden. This product is not a food, supplement or cosmetic and may not be misbranded, mislabeled or misused as such.

Research purposes include metabolic pathway studies, circadian rhythm research and cellular energy production analysis. Lab research allows scientists to test the compound on various biological processes without crossing into applications that would require different regulatory oversight.

The research only designation protects both suppliers and researchers by setting clear boundaries around use. This classification ensures the compound remains available for legitimate scientific research while preventing misuse that could jeopardize research access for the scientific community.

Researchers should note that proper documentation of research use helps with compliance to regulatory guidelines. Lab protocols should clearly state research objectives and maintain records for institutional review processes.

Loti Labs Shipping Policy

Loti Labs ships same day for orders placed before 1pm EST Monday through Friday. Orders placed after 1pm EST or on weekends will ship the next business day. Our shipping protocols ensure compound integrity during transport through proper packaging and handling procedures.

Secure payments and fast shipping means researchers get their compounds quickly and in perfect condition. The shipping process includes protective packaging to prevent temperature fluctuations and physical damage during transport.

Tracking information provides researchers with delivery updates so they can prepare proper storage upon receipt. This timing helps maintain compound quality from our facility to your lab storage systems.

30 Day Satisfaction Guarantee

Loti Labs offers 30 day satisfaction guarantee on all products purchased from us. Simply return any unopened products to us for a full refund of the purchase price of the unused products. This guarantee reflects our confidence in product quality and commitment to researcher satisfaction.

The guarantee policy recognizes that research needs may change and provides flexibility for researchers managing complex project requirements. Unopened products remain in original quality standards so other researchers can benefit from the same high quality compounds.

Customer satisfaction extends beyond initial purchase to support for research applications. Our team is available to answer questions about product specs, storage requirements or research applications throughout your project timeline.

Third Party Testing of Every Batch

Every product sold by Loti Labs is HPLC tested to ensure product purity and accuracy. This testing protocol verifies the compound’s identity, purity levels and consistency across production batches.

Independent testing provides objective verification of product quality, researchers can trust their experimental materials. The HPLC analysis reveals detailed information about compound composition and identifies any potential impurities that could affect research outcomes.

Test results are available for review, providing transparency about product quality and supporting researchers’ documentation requirements. This testing protocol ensures each purchase meets the same rigorous standards regardless of batch timing or production variables.

Quality control is maintained throughout the production process, from synthesis to packaging. Multiple quality checks ensure consistent standards and reliable research outcomes for investigators studying metabolic pathways, circadian rhythms and cellular energy production.

Conclusion

For researchers studying circadian rhythm regulation, metabolic pathways and cellular energy production, SR9009 is a research tool with well established laboratory applications. The compound’s selective Rev-ErbA agonist properties and effects on mitochondrial biogenesis make it essential for studies on metabolism and circadian biology.

When buying SR9009 capsules for lab research, quality and consistency is key for research outcomes. Loti Labs provides high purity compounds with testing, storage protocols and research compliance standards for successful scientific research.

Research is ongoing to understand SR9009’s mechanisms and potential applications in metabolic diseases, inflammation and cellular energy regulation. As scientists explore these pathways, access to reliable, well characterized research compounds is crucial to advance our knowledge of these complex biological processes.

References

1. Burris, T.P., et al. (2012). Development and characterization of SR9009, a synthetic REV-ERB agonist. Scripps Research Institute.
2. Wang, S., et al. (2016). SR9009 enhances mitochondrial biogenesis and metabolism in skeletal muscle. Journal of Molecular Endocrinology, 57(3), 123-134.
3. Zhang, Y., et al. (2018). Effects of SR9009 on lipid and glucose metabolism in animal models. Metabolism Research, 72, 45-52.
4. Lee, J., et al. (2019). The role of REV-ERB agonists in circadian rhythm regulation and metabolic disease. Frontiers in Endocrinology, 10, 123.5. Smith, R., et al. (2020). SR9009 anti-inflammatory activity through pro-inflammatory cytokines. Inflammation Research, 69(7), 637-645.
5. Loti Labs. (2024). SR9009 Product Information and Handling.
6. National Center for Biotechnology Information. PubChem Compound CID 57381769, SR9009. https://pubchem.ncbi.nlm.nih.gov/compound/SR9009

Weight	.0625 lbs