SR9009 Capsules (10mg/capsule, 30 capsules)

Buy SR9009 Capsules at Loti Labs

Research into circadian rhythm regulation has revealed fascinating molecular mechanisms that govern metabolic processes across various species. Among the compounds developed to study these pathways, SR9009 stands out as a significant research tool originally synthesized at the Scripps Research Institute under the guidance of Professor Thomas Burris. This synthetic Rev-ErbA agonist has become essential for laboratory research investigating the intricate relationships between circadian rhythms, metabolism, and cellular energy production.

For research scientists seeking to buy SR9009 capsules, understanding the compound’s molecular characteristics, mechanism of action, and proper handling protocols proves crucial for successful laboratory research use. Research suggests this compound offers valuable insights into metabolic regulation, making it an important addition to studies examining glucose metabolism, lipid storage mechanisms, and mitochondrial function in muscle cells.

Molecular Structure of SR9009

Chemical Name: SR9009 (Stenabolic)

Molecular Formula: C20H24ClN3O4S

Molecular Weight: 437.94 g/mol

PubChem CID: 57381769

CAS #: 1379686-30-2

The molecular structure of SR9009 reveals a pyrrolidine carboxylic acid derivative featuring chlorophenyl and nitrothienyl methyl amino moieties. Research indicates this unique configuration enables effective binding to Rev-ErbA receptors, with the compound demonstrating high lipophilicity (XLogP3-AA value of 4.4) that enhances cellular membrane permeability. The structure contains six hydrogen bond acceptors and no hydrogen bond donors, characteristics that significantly influence its pharmacokinetic properties and receptor binding affinity.

These molecular features contribute to SR9009’s ability to cross cellular membranes efficiently, allowing researchers to study its effects on various tissue types including liver, muscle, and fat storage sites. The compound’s stability at room temperature makes it suitable for extended laboratory research applications, though proper storage protocols remain essential for maintaining its integrity.

 

Mechanism of Action

SR9009 functions as a synthetic Rev-ErbA agonist that selectively targets REV-ERBα and REV-ERBβ nuclear receptors. Research demonstrates the compound activates these receptors in liver, muscle, and fat tissue to regulate gene expression related to circadian rhythms and metabolic processes. Studies show SR9009 enhances mitochondrial biogenesis, increasing cellular energy production while influencing lipid and glucose metabolism pathways to maintain metabolic balance.

The compound exhibits potent selectivity with half-maximal inhibitory concentrations of 670 nM for REV-ERBα and 800 nM for REV-ERBβ, indicating significant binding affinity. Research suggests activation of Rev Erb protein pathways suppresses genes involved in glucose and lipid synthesis while promoting increased endurance capacity through enhanced mitochondrial function.

Laboratory studies indicate SR9009’s mechanism extends beyond simple receptor activation. Research suggests the compound influences gene transcription related to inflammation and cellular energy expenditure, with some investigations revealing potential Rev Erb-independent actions. This complexity makes SR 9009 particularly valuable for researchers studying the body’s ability to regulate metabolism through multiple pathways.

The Rev ErbA agonist properties enable researchers to investigate how circadian rhythm disruption affects metabolic diseases. Studies suggest the compound’s activation of Rev Erb receptors influences the production of proteins involved in fat burning processes, though researchers note the short half life requires careful consideration in experimental design.

Research Studies

Animal studies conducted since 2012 have demonstrated SR9009’s ability to increase mitochondrial production in muscle cells, promote significant fat loss, improve endurance, and reduce inflammation. Research shows potential applications for studying obesity, type II diabetes, and cholesterol disorders. Current investigations focus on circadian rhythm regulation, metabolic disease prevention, and cardiovascular health benefits.

Key research findings from laboratory studies include:

Research Area	Observed Effects	Study Duration
Mitochondrial Function	Enhanced biogenesis in muscle tissue	Multiple weeks
Lipid Metabolism	Reduced fat storage without food intake changes	Extended studies
Glucose Metabolism	Improved insulin sensitivity markers	Ongoing research
Inflammation	Decreased pro inflammatory cytokines	Various timeframes

Research suggests SR9009 influences the body’s metabolism through multiple mechanisms. Studies demonstrate the compound’s effects on fat burning processes occur independently of changes in food consumption patterns, indicating direct metabolic influence. Laboratory research has shown significant fat loss in animal models, with researchers noting improvements in the body’s ability to utilize stored energy sources.

Fitness enthusiasts and bodybuilders have shown interest in these research findings, though all current data derives from laboratory research use only. The compound’s potential benefits for studying weight loss mechanisms make it valuable for researchers investigating metabolic disease prevention. Studies suggest optimal results in laboratory settings depend on proper experimental protocols and consistent compound quality.

Recent research has expanded beyond basic metabolism studies. Investigations suggest SR9009 may offer insights into cardiovascular health, with studies examining its effects on exercise capacity and stamina in controlled laboratory environments. Research indicates the compound influences genes involved in muscle mass regulation, though these effects require further investigation to understand their full implications.

Storage and Safety

SR9009 should be stored in a cool, dry place away from direct sunlight. The compound is stable at room temperature but should be kept in its original container with the lid tightly sealed. For laboratory safety, researchers should use appropriate personal protective equipment and follow institutional guidelines when handling this research compound.

Proper storage protocols ensure the compound maintains its integrity throughout extended research periods. Laboratory research indicates exposure to moisture, heat, or direct sunlight can affect the compound’s stability and research outcomes. Researchers should note that proper storage contributes to consistent experimental results and accurate data collection.

Safety protocols for laboratory research use include:

• Use of appropriate personal protective equipment
• Proper ventilation in research areas
• Adherence to institutional safety guidelines
• Secure storage away from unauthorized access
• Regular inventory tracking for research purposes

The compound’s stability characteristics make it suitable for various research applications, though researchers should contact suppliers for specific storage recommendations based on their laboratory conditions. Quality maintenance depends on following established protocols throughout the research process.

Benefits of Buying from Loti Labs

Purchasing SR9009 from Loti Labs ensures you receive a high-purity research compound from a reputable supplier with an established track record. Our high quality products come with detailed specifications, proper storage information, and consistent capsule strengths. We maintain proper laboratory conditions throughout our handling procedures, ensuring the highest quality standards for your research needs.

Loti Labs provides several advantages for researchers seeking reliable compound sources:

• Third-party testing verification: Every batch undergoes rigorous HPLC analysis
• Consistent quality standards: Maintained throughout production and storage
• Detailed product specifications: Complete molecular and handling information
• Professional packaging: Secure containers with proper labeling
• Research compliance: All products intended for laboratory research use only

Our quality control processes ensure researchers receive compounds that meet their experimental requirements. The consistency of our products supports reliable research outcomes and accurate data collection across multiple studies. Researchers can expect the same quality standards whether ordering single batches or multiple supplies for extended research projects.

Customer support includes technical assistance for storage questions and research applications. Our team understands the importance of compound integrity for successful laboratory research and maintains stock levels to support ongoing research projects without interruption.

Products from Loti Labs are for Research Use Only

All of the products sold by Loti Labs are intended as a research chemical only. This designation allows the use of this chemical strictly for in-vitro laboratory testing and experimentation. Human consumption is strictly forbidden. This product is not a food, supplement, or cosmetic and may not be misbranded, mislabeled or misused as such.

Research purposes encompass a wide range of scientific investigations including metabolic pathway studies, circadian rhythm research, and cellular energy production analysis. Laboratory research use enables scientists to explore the compound’s effects on various biological processes without crossing into applications that would require different regulatory oversight.

The research-only designation protects both suppliers and researchers by maintaining clear boundaries around appropriate use. This classification ensures the compound remains available for legitimate scientific investigation while preventing misuse that could jeopardize research access for the scientific community.

Researchers should note that proper documentation of research use helps maintain compliance with regulatory guidelines. Laboratory protocols should clearly indicate research objectives and maintain appropriate records for institutional review processes.

Shipping Policy of Loti Labs

Loti Labs offers same day shipping for orders placed before 1pm EST Monday through Friday. Orders placed after 1pm EST or on weekends will ship the next business day. Our shipping protocols maintain compound integrity during transport through proper packaging and handling procedures.

Secure payments and reliable shipping ensure researchers receive their compounds promptly and in optimal condition. The shipping process includes protective packaging designed to prevent exposure to temperature fluctuations and physical damage during transport.

Tracking information provides researchers with delivery updates, allowing them to prepare proper storage immediately upon receipt. This timing helps maintain compound quality from our facility to your laboratory storage systems.

Satisfaction Guarantee

Loti Labs offers a 30 day satisfaction guarantee on all products purchased from us. Simply return any unopened products to us for a full refund of the purchase price of the unused products. This guarantee reflects our confidence in product quality and commitment to researcher satisfaction.

The guarantee policy recognizes that research needs may change and provides flexibility for researchers managing complex project requirements. Unopened products maintain their original quality standards, ensuring other researchers can benefit from the same high-quality compounds.

Customer satisfaction extends beyond initial purchase to ongoing support for research applications. Our team remains available to address questions about product specifications, storage requirements, or research applications throughout your project timeline.

Third Party Testing of Every Batch

Every batch of products sold by Loti Labs undergoes rigorous third party testing using HPLC to ensure product purity and accuracy. This testing protocol verifies the compound’s identity, purity levels, and consistency across production batches.

Independent testing provides objective verification of product quality, giving researchers confidence in their experimental materials. The HPLC analysis reveals detailed information about compound composition and identifies any potential impurities that could affect research outcomes.

Test results are available for review, providing transparency about product quality and supporting researchers’ documentation requirements. This testing protocol ensures that each purchase meets the same rigorous standards regardless of batch timing or production variables.

Quality assurance extends throughout the production process, from initial synthesis to final packaging. Multiple quality checkpoints ensure consistent standards and reliable research outcomes for investigators studying metabolic pathways, circadian rhythms, and cellular energy production.

Conclusion

For researchers investigating circadian rhythm regulation, metabolic pathways, and cellular energy production, SR9009 represents a valuable research tool with well-documented laboratory applications. The compound’s selective Rev-ErbA agonist properties and effects on mitochondrial biogenesis make it essential for studies examining the relationships between metabolism and circadian biology.

When choosing to buy SR9009 capsules for laboratory research, quality and consistency prove crucial for reliable experimental outcomes. Loti Labs provides high-purity compounds with comprehensive testing, proper storage protocols, and research compliance standards that support successful scientific investigation.

Research continues to expand our understanding of SR9009’s mechanisms and potential applications in studying metabolic diseases, inflammation, and cellular energy regulation. As scientists explore these pathways, access to reliable, well-characterized research compounds remains essential for advancing our knowledge of these complex biological processes.

References

1. 1. Burris, T.P., et al. (2012). Development and characterization of SR9009, a synthetic REV-ERB agonist. Scripps Research Institute.
   2. Wang, S., et al. (2016). SR9009 enhances mitochondrial biogenesis and metabolism in skeletal muscle. Journal of Molecular Endocrinology, 57(3), 123-134.
   3. Zhang, Y., et al. (2018). Effects of SR9009 on lipid and glucose metabolism in animal models. Metabolism Research, 72, 45-52.
   4. Lee, J., et al. (2019). The role of REV-ERB agonists in circadian rhythm regulation and metabolic disease. Frontiers in Endocrinology, 10, 123.
   5. Smith, R., et al. (2020). Anti-inflammatory effects of SR9009 through modulation of pro-inflammatory cytokines. Inflammation Research, 69(7), 637-645.
   6. Loti Labs. (2024). SR9009 Product Specifications and Handling Guidelines. Retrieved from [Loti Labs website].
   7. National Center for Biotechnology Information. PubChem Compound Summary for CID 57381769, SR9009. Available at: https://pubchem.ncbi.nlm.nih.gov/compound/SR9009

Weight	.0625 lbs