Semaglutide 5mg

Buy Semaglutide Peptide for sale at Loti Labs

Semaglutide peptide, a synthetic hormone, functions by mimicking GLP-1 in research settings to regulate glucose and potentially influence appetite regulation. This article covers the research mechanisms, potential benefits, research observations, and scientific findings.

 

Understanding Semaglutide Peptide

Semaglutide is a synthetic analogue of the GLP-1 hormone, specifically designed for investigation in type 2 diabetes and obesity research with animal models. This peptide mimics the actions of GLP-1, a hormone that plays a crucial role in glucose regulation and appetite signaling. Available under the brand name Wegovy, semaglutide has garnered significant interest due to its potential applications in weight-related studies and its classification among approved compounds.

Classified as a glucagon-like peptide-1 (GLP-1) receptor agonist, semaglutide stimulates the GLP-1 receptors in the brain, which leads to various physiological responses that can affect metabolism and body composition in research settings. Understanding its molecular structure and mechanism of action allows researchers to appreciate its potential benefits and applications in controlled laboratory studies.

Molecular Structure and Formula

The molecular formula of semaglutide is C187H291N45O59, and it has a molecular weight of 4113.64 g/mol. This intricate structure is crucial for its effectiveness in research contexts, providing the foundation for its interaction with GLP-1 receptors.

Mechanism of Action

Semaglutide functions by mimicking the natural GLP-1 hormone, enhancing glucose-dependent insulin secretion while simultaneously lowering blood sugar levels and glucagon levels in laboratory models. This dual action contributes to improved insulin response, which is essential for regulating blood sugar levels and maintaining metabolic parameters in research settings.

Moreover, semaglutide decreases glucagon production, further aiding in blood sugar regulation in test subjects. By activating GLP-1 receptors, research suggests semaglutide can also reduce appetite and decrease food intake, providing a potential mechanism for weight reduction in animal models. This complex interplay of processes highlights the peptide’s multifaceted role in metabolic research.

Research Applications of Semaglutide

Research on semaglutide extends beyond its molecular structure and mechanism of action to its applications in managing weight and metabolic conditions in animal studies. As a synthetic analogue of the GLP-1 hormone, semaglutide has shown promise in research models of type 2 diabetes and obesity. Research suggests that it may offer significant benefits in chronic weight management studies and cardiovascular health investigations.

Investigating its effects in animal studies helps to unravel semaglutide’s potential in various research applications. This section explores its impact on chronic weight management and cardiovascular health research, shedding light on the ongoing studies and findings in these areas.

Proper Usage and Storage for Research

Proper usage and storage of semaglutide are vital for maintaining its effectiveness in research applications. Semaglutide must be stored in a freezer at -20°C to preserve its stability and potency. Before use, it should be kept in a refrigerator between 2°C to 8°C.

Once opened, semaglutide can be maintained at room temperature (15°C to 30°C) for up to 56 days, ensuring its usability over an extended research period. Handling semaglutide with care is essential to prevent degradation and ensure accurate research outcomes.

Summary

Research suggests that semaglutide presents a compelling case for its potential metabolic health investigations. By mimicking GLP-1, it may offer mechanisms for appetite suppression, blood sugar regulation, and possibly cardiovascular benefits, as indicated by animal studies. However, safety considerations, particularly gastrointestinal reactions, must be carefully managed to ensure effective usage in research settings.

As investigations continue to explore the complexities of semaglutide, it stands as a promising tool in the study of obesity and metabolic disorders. Ongoing studies and findings pave the way for a more comprehensive understanding and application of this peptide in scientific research.

Frequently Asked Questions

What is the molecular weight of Semaglutide?

The molecular weight of Semaglutide is 4113.64 g/mol.

What is the recommended storage temperature for lyophilized Semaglutide?

The recommended storage temperature for lyophilized Semaglutide is -20°C. This temperature ensures the stability and efficacy of the compound.

References and Citations

1. Wilding, J. P. H., et al. (2021). “Once-Weekly Semaglutide in Adults with Overweight or Obesity.” New England Journal of Medicine, 384(11), 989-1002. doi:10.1056/NEJMoa2032183.
2. Davies, M., et al. (2017). “Semaglutide as a Treatment for Type 2 Diabetes.” Diabetes Care, 40(7), 951-960. doi:10.2337/dc16-1390.
3. Marso, S. P., et al. (2016). “Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.” New England Journal of Medicine, 375(19), 1834-1844. doi:10.1056/NEJMoa1607141.
4. Blundell, J., et al. (2017). “Effects of once-weekly semaglutide on appetite, energy intake, control of eating, and food preference in subjects with obesity.” Diabetes, Obesity and Metabolism, 19(9), 1242-1251. doi:10.1111/dom.12932.
5. Nauck, M. A., et al. (2021). “Semaglutide for the treatment of type 2 diabetes and obesity: a review.” Frontiers in Endocrinology, 12, 645930. doi:10.3389/fendo.2021.645930.
6. Wadden, T. A., et al. (2021). “Weight reduction and improvement in glycaemic control with semaglutide in obese patients with type 2 diabetes.” Diabetes, Obesity and Metabolism, 23(1), 102-112. doi:10.1111/dom.14234.
7. Kushner, R. F., et al. (2020). “Semaglutide 2.4 mg for the treatment of obesity: a review of the STEP trials.” Obesity, 28(6), 1050-1062. doi:10.1002/oby.22813.

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Weight	0.0099 lbs
Appearance	Lyophilized Powder
Peptide Sequence	HXEGTFTSDVSSYLEGQAAK-OH.steric diacid-EFIAWLVRGRG
Solubility	100 µg/mL sterile diluent
Source	Biosynthetic production
Stability	Lyophilized protein is to be stored at -20°C. It is recommended to divide the remaining reconstituted peptide into multiple vials so as to avoid a cycle of freezing and thawing. Reconstituted protein can be stored at 4°C.
Molecular Weight	4113.64 g/mol
Synonyms	Semaglutide, Rybelsus, NN9535
CAS Number	910463-68-2
PubChem	CID 56843331
Molecular Formula	C187H291N45O59
MG	5mg
Terms	This product is sold for research/laboratory usage only. No other uses are permited.

 

Weight	.03125 lbs