MOTS-c 10mg

Buy MOTS-c at Loti Labs: Complete Research Guide

Research into mitochondrial derived peptides has unveiled remarkable insights into cellular metabolism and energy homeostasis. Scientists seeking to buy mots c for laboratory investigations require compounds that meet rigorous purity standards with comprehensive analytical documentation. MOTS-c, a 16-amino acid mitochondrial encoded peptide mots, represents a critical research tool for studying metabolic regulation and aging processes in controlled experimental settings.

The mitochondrial derived peptide mots c originates from the mitochondrial genome, specifically encoded within the 12S rRNA gene’s open reading frame. Research suggests this peptide mots c plays essential roles in systemic metabolism, making it an invaluable compound for researchers investigating cellular metabolism and metabolic homeostasis mechanisms.

Molecular Structure of MOTS-c

The derived peptide mots c consists of a precisely defined 16-amino acid sequence containing arginine (Arg), tryptophan (Trp), glutamine (Gln), glutamic acid (Glu), glycine (Gly), tyrosine (Tyr), isoleucine (Ile), and phenylalanine (Phe). The complete sequence follows the pattern: arg trp gln glu-Met-gly tyr ile phe-Tyr-Pro-Arg-Lys-Leu-Arg, representing a compact yet functionally significant peptide structure.

Key Molecular Characteristics:

Property	Value
Amino Sequence	16-amino acid peptide containing Arg, Trp, Gln, Glu, Gly, Tyr, Ile, and Phe
Molecular Formula	C97H146N30O32
Molecular Weight	2174.59 Daltons
PubChem CID	91758452
CAS Number	1360004-48-5
This mitochondria derived peptide represents one of several mitochondrial derived peptides that researchers have identified as emerging from the mitochondrial open reading frame. The molecular weight of approximately 2174.59 Daltons places mots c within an optimal range for cellular uptake and biological activity in experimental systems.

Mechanism of Action

The mots c peptide functions as a key regulator of metabolic processes through its interaction with the amp activated protein kinase pathway. Research suggests that maintaining mitochondrial function requires precise coordination between nuclear genomes and mitochondrial-derived signaling molecules like the mitochondrial derived peptide mots.

Experimental investigations demonstrate that mots c treatment influences glucose metabolism through ampk activation. The peptide appears to regulate nuclear gene expression by modulating the folate cycle and affecting cellular metabolism pathways. Studies indicate that mots c administration can improve insulin sensitivity in skeletal muscle tissue through enhanced glucose uptake mechanisms.

Primary Research Targets:

• AMPK Pathway Activation: Research suggests the ampk pathway serves as a central target for mots c peptide activity
• Glucose Homeostasis: Experimental data indicates effects on glucose utilization and glucose metabolism
• Lipid Metabolism: Findings suggest influences on fat metabolism and adipose homeostasis
• Insulin Sensitivity: Laboratory studies show potential effects on insulin resistance mechanisms

The aging process naturally reduces circulating mots c levels, making this compound particularly relevant for research into age related diseases and metabolic dysfunction. Experimental evidence suggests that mots c plays roles in muscle metabolism and maintaining cellular energy balance during metabolic stress conditions.

Research Studies

Extensive laboratory investigations have explored the mitochondrial encoded peptide mots across multiple research domains. Scientists investigating metabolic regulation utilize mots c in receptor-ligand binding studies, enzyme activity assays, and cell proliferation experiments to understand its biochemical mechanisms.

Current Research Applications:

• Metabolic Studies: Researchers examine glucose homeostasis and systemic metabolism responses
• Cellular Metabolism: Investigations focus on mitochondrial function and energy production pathways
• Bone Research: Studies explore effects on mesenchymal stem cells and promoting osteogenic differentiation
• Cardiovascular Research: Experimental work examines endothelial function and coronary endothelial dysfunction
• Aging Research: Laboratory studies investigate age dependent physical decline and exceptional longevity mechanisms

Research suggests that mots c promotes various cellular responses through endothelial cells and stem cells interactions. The same study methodologies that revealed mots c improves osteoporosis-related parameters in experimental models continue to guide current investigations. Kim et al and other research groups have demonstrated that findings suggest significant potential for understanding metabolic disorders through this mitochondrial derived peptide.

Experimental protocols frequently examine how mots c inhibits certain pathways while simultaneously promoting others, particularly in contexts involving diet induced obesity models and ovariectomy induced metabolic dysfunction studies. Cell viability assays and bone marrow investigations provide additional research avenues for understanding this compound’s mechanisms.

Storage and Safety

Proper handling protocols ensure optimal stability and experimental consistency when researchers buy mots c for laboratory applications. The lyophilized peptide requires specific storage conditions to maintain molecular integrity throughout experimental timeframes.

Storage Requirements:

• Initial Storage: Store at 4°C or colder upon receipt
• Long-term Preservation: -20°C recommended for extended stability periods
• Environmental Protection: Shield from bright light and moisture exposure
• Handling Protocol: Allow vials to equilibrate to room temperature before opening
• Reconstituted Solutions: Remain stable for 3+ weeks at +4°C and 3-4 months at -20°C

Laboratory safety protocols require adherence to institutional guidelines for peptide handling. Researchers should implement appropriate personal protective equipment and follow established procedures for working with research compounds. The mots c 10mg vial format provides convenient quantities for most experimental protocols while minimizing waste.

Benefits of Buying from Loti Labs

Loti Labs provides high-purity mots c suitable for demanding research applications with comprehensive analytical documentation. Each batch undergoes rigorous quality control measures to ensure researchers receive compounds meeting exacting scientific standards.

Quality Assurance Features:

• Purity Verification: Certificates of analysis demonstrate purity levels above 99%
• Sequence Confirmation: Proper peptide sequencing verification through advanced analytical methods
• Molecular Weight Validation: Precise molecular weight confirmation using mass spectrometry
• Packaging Excellence: Glass vial packaging ensures optimal preservation and stability
• Documentation: Complete analytical profiles accompany every shipment

The commitment to good manufacturing practices (GMP) ensures batch-level consistency crucial for reproducible experimental results. Independent third-party verification provides additional confidence in compound quality and identity confirmation.

Products from Loti Labs are for Research Use Only

All compounds sold by Loti Labs are designated strictly as research chemicals for laboratory applications. This classification permits use exclusively for in-vitro testing, biochemical studies, and controlled experimental investigations. The designation specifically prohibits human or veterinary applications under federal regulations.

Important Compliance Information:

• Products are not approved as pharmaceutical compounds, food additives, or cosmetic ingredients
• Compounds cannot be misbranded, mislabeled, or misused outside research contexts
• All purchases must comply with federal, state, and institutional regulations
• Laboratory use requires appropriate safety protocols and trained personnel

Researchers must ensure their investigations align with established research use only guidelines. Institutional review and approval may be required depending on specific experimental protocols and research objectives.

Shipping Policy of Loti Labs

Loti Labs maintains efficient shipping procedures to support ongoing research timelines. Orders placed before 1pm EST Monday through Friday receive same-day processing and shipment. Orders submitted after 1pm EST or during weekends ship on the next business day.

Available Concentrations and Shipping:

• Standard vial sizes: 10mg
• Discreet packaging maintains confidentiality
• Secure delivery options with tracking capabilities

The streamlined ordering process accommodates research laboratory schedules while ensuring proper handling throughout the delivery chain.

Satisfaction Guarantee

Loti Labs supports research endeavors with a comprehensive 30-day satisfaction guarantee. Researchers may return unopened products for full refunds of the purchase price, providing additional security for laboratory procurement decisions.

This guarantee reflects confidence in product quality and manufacturing standards. The policy accommodates changing research priorities and experimental requirements while maintaining fiscal responsibility for research budgets.

Third Party Testing of Every Batch

Rigorous third-party testing protocols validate every batch of compounds sold by Loti Labs. High-performance liquid chromatography (HPLC) analysis confirms product purity and identity, while mass spectrometry provides molecular weight verification.

Quality Control Measures:

• Independent laboratory verification for each production batch
• HPLC purity analysis with detailed chromatographic profiles
• Mass spectrometry confirmation of molecular identity
• Good manufacturing practices (GMP) compliance throughout production
• Comprehensive documentation accompanying each shipment

These analytical procedures ensure researchers receive consistent, high-quality compounds suitable for demanding experimental applications. The independent verification process eliminates potential variability and supports reproducible research outcomes.

Conclusion

The mitochondrial derived peptide mots c represents a valuable research tool for investigating cellular metabolism, aging processes, and metabolic regulation mechanisms. Scientists seeking to buy mots c require suppliers that prioritize analytical verification, proper documentation, and regulatory compliance.

Loti Labs addresses these requirements through comprehensive quality assurance programs, third-party testing protocols, and research-focused customer support. The combination of high-purity compounds, detailed analytical documentation, and efficient shipping procedures supports productive laboratory investigations across multiple research domains.

For researchers investigating metabolic homeostasis, mitochondrial function, or age-related cellular processes, Loti Labs provides the analytical rigor and product consistency essential for meaningful scientific discoveries. Contact Loti Labs to discuss specific research requirements and compound specifications for your next investigation.

References

1. 1. Lee C, Zeng J, Drew BG, et al. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metab. 2015;21(3):443-454. doi:10.1016/j.cmet.2015.02.009
   2. Kim KH, Son JM, Benayoun BA, Lee C. The mitochondrial-encoded peptide MOTS-c translocates to the nucleus to regulate nuclear gene expression in response to metabolic stress. Cell Metab. 2018;28(4):516-524.e7. doi:10.1016/j.cmet.2018.07.003
   3. Lu Y, Zhang Y, Wang X, et al. MOTS-c suppresses colorectal cancer cell growth by regulating metabolic homeostasis. Aging (Albany NY). 2020;12(15):15331-15344. doi:10.18632/aging.103791
   4. Reynolds JC, Kim KH, Srikantan S, et al. Mitochondrial-derived peptides in aging and healthspan. Trends Endocrinol Metab. 2021;32(5):349-360. doi:10.1016/j.tem.2020.12.006
   5. Fuku N, Park KS, Yamada Y, et al. Mitochondrial haplogroup and longevity: a study in the Japanese population. Aging Cell. 2015;14(1):21-28. doi:10.1111/acel.12270
   6. Lu Z, Li J, Wang J, et al. MOTS-c improves osteoporosis by promoting osteogenic differentiation via the TGF-β/Smad pathway. J Bone Miner Res. 2021;36(8):1465-1477. doi:10.1002/jbmr.4316
   7. Reynolds JC, Lee C. MOTS-c: a mitochondrial-encoded regulator of metabolic homeostasis and physical activity. Trends Endocrinol Metab. 2020;31(7):489-498. doi:10.1016/j.tem.2020.04.004
   8. Zhai M, Zhang Z, Zhang X, et al. MOTS-c alleviates ovariectomy-induced metabolic dysfunction by enhancing brown fat activation and reducing fat accumulation. Metabolism. 2022;130:155175. doi:10.1016/j.metabol.2022.155175
   9. Kim KH, Son JM, Lee C. MOTS-c: a mitochondrial-derived peptide regulating muscle homeostasis and metabolic processes. J Physiol. 2019;597(15):3737-3746. doi:10.1113/JP277534
   10. Lee C, Zeng J, Drew BG, et al. Mitochondrial peptides and metabolic regulation: implications for cardiovascular diseases and aging. J Mol Cell Cardiol. 2016;95:1-7. doi:10.1016/j.yjmcc.2015.12.012

Weight	.03125 lbs