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    Buy Melanotan 2 at Loti Labs

    Research into melanocortin receptor pathways has come a long way thanks to high quality synthetic peptide analogues. Scientists studying pigmentation, metabolic regulation and neuroendocrine functions need reliable access to research grade compounds that meet analytical standards. When researchers need to buy melanotan 2 for lab work the quality and purity of the synthetic melanocortin receptor agonist is key to reproducible results.

    Melanotan II is a key tool in melanocortin system research, allowing scientists to study complex physiological systems in controlled lab experiments. The compound is a potent activator of melanocortin receptors across multiple subtypes, making it essential for researchers investigating pigmentation, food intake regulation and sexual functions in various models.

    Molecular Structure of Melanotan 2

    The molecular structure of mt ii reflects sophisticated peptide engineering to enhance stability and receptor selectivity. Understanding the structure is important for experimental design and handling protocols.

    Amino Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2

    Molecular Formula: C50H69N15O9

    Molecular Weight: 1024.2 g/mol

    PubChem CID: 9831659

    CAS #: 121062-08-6

    The peptide hormone structure has several key modifications that distinguish it from the endogenous α msh. The ac nle terminus provides stability, the cyclic configuration created by the phe arg trp lys sequence improves receptor binding and research suggests it’s more potent than linear analogues.

    The synthesis process is around 12 steps with careful attention to the cyclization mechanism. Scientists note that the lactam bridge formation between specific amino acid residues creates the compound’s 3D structure which is essential for melanocortin receptor recognition and activation.

    Mechanism of Action

    Melanotan 2 is a synthetic melanocortin receptor agonist that is non selective across multiple melanocortin receptors. Research shows it primarily targets MC1R, MC3R, MC4R and MC5R each involved in different physiological pathways that researchers study through experimentation.Originally developed at the University of Arizona in the 80s this compound has specific binding affinity for melanocortin receptors with measurable EC50 values in lab studies. The mechanism is to mimic the natural signaling of α-melanocyte-stimulating hormone while providing stability and bioavailability for research use.

    Receptor Type Primary Research Focus Experimental Applications
    MC1R Pigmentation pathways Melanogenesis studies
    MC3R Metabolic regulation Energy homeostasis research
    MC4R Appetite and sexual functions Feeding behavior studies
    MC5R Exocrine gland function Sebaceous gland research

    Lab studies show MT-II activation of MC1R directly stimulates melanogenesis and increases eumelanin production in melanocyte cultures. Research shows MC4R binding effects lead to changes in food intake patterns when administered to experimental mouse models. Also cavernous nerve stimulation responses can be influenced through melanocortin receptor pathways but the exact mechanisms need to be further studied.

    The compound can cross biological barriers making it very useful for researchers studying central nervous system melanocortin functions. Experiments involving intracerebroventricular administration have provided data on appetite regulation and thermogenic responses in lab settings.

    Essential Key Takeaways for Melanotan 2 10mg Product

    Research applications of Melanotan 2 involve various experimental approaches across multiple scientific disciplines. Lab studies focus on melanocortin receptor pathways and signaling mechanisms providing researchers with data on complex physiological processes.

    In-vitro studies examining receptor-ligand binding assays are the foundation of melanotan research. Scientists perform concentration-response experiments to determine binding specificity and measure downstream signaling cascades. These experiments typically involve transfected cell lines expressing individual melanocortin receptors allowing researchers to isolate specific pathway responses.

    Cell proliferation and differentiation studies are another area of research. Lab data shows melanocortin receptor activation influences cellular development patterns especially in melanocyte cultures. Researchers studying pigmentation mechanisms rely on these experimental systems to understand how receptor activation leads to increased melanin synthesis.

    Animal model research has provided a lot of data on systemic effects after compound administration. Studies in mice and rats have examined various parameters including body weight changes, feeding behavior modifications and erectile responses in male subjects. Research suggests peripheral nerve regeneration may also be influenced by melanocortin receptor activation but this area needs further study.Behavioral research applications include appetite suppression and sexual arousal studies. Scientists have documented that administration of mt ii in lab settings can produce measurable changes in feeding patterns and sexual functions across different species. The first erectile event timing and erectile dysfunction research models have used this compound to study melanocortin pathway involvement in reproductive physiology.

    Glucose metabolism studies examine whether melanotan ii affects metabolic markers through MC4R or other pathways. Researchers have looked at insulin sensitivity and glucose uptake after compound treatment in various models. These studies contribute to understanding metabolic regulation at the cellular level.

    Storage and Safety

    Proper storage protocols ensure melanotan 2 remains structurally intact and biologically active throughout the research period. Scientists must follow specific handling procedures to prevent peptide degradation and experimental consistency.

    Store lyophilized melanotan 2 at 4°C or colder, protected from light to prevent photodegradation. For long term storage store at -20°C or colder in a laboratory freezer. Research facilities should note that temperature fluctuations can affect peptide stability and experimental reproducibility.

    Allow peptides to come to room temperature before opening sealed containers to minimize moisture exposure. This equilibration step prevents condensation formation that can lead to peptide hydrolysis or aggregation. Scientists should avoid repeated freeze-thaw cycles to prevent peptide degradation as structural changes can affect receptor binding.

    Prepared solutions are stable for approximately 3 weeks at +4°C and 3-4 months at -20°C under lab conditions. Researchers should prepare working solutions in appropriate buffers and store in sterile containers to prevent contamination. The solubility of the compound allows for preparation in various aqueous solutions for different experimental protocols.

    Lab safety protocols require proper ventilation and personal protective equipment when handling peptide powders. Research facilities should keep records of storage conditions and expiration dates to ensure experimental validity. Also proper disposal procedures must follow institutional guidelines for research chemicals.

    Why Buy from Loti Labs

    Loti Labs offers high quality melanotan 2 with verified purity and composition data for scientific research. Each product comes with a certificate of analysis showing HPLC and mass spectrometry results for peptide identity confirmation so researchers get authentic compounds for their research.We control the environment during shipping and handling with sterility testing for all research grade materials. We have specialized cold-chain logistics to preserve peptide integrity from manufacturing to delivery to research facilities. This environmental control prevents degradation that can affect experimental results.

    We keep consistent stock levels and provide detailed analytical data for research applications. Scientists can access batch specific data including purity analysis, molecular weight confirmation and sequence verification. This data supports regulatory compliance for academic institutions and research facilities.

    The concentration and peptide form meets research grade standards for reproducible experiments. Our quality assurance includes testing for common contaminants and verification of amino acid sequence. Research shows that consistent peptide quality correlates with experimental reproducibility across different lab settings.

    Third party analytical services provide independent verification of compound identity and purity. These external labs use advanced analytical techniques to confirm molecular structure and detect impurities. The data gives researchers confidence in their experimental materials and supports publication requirements.

    Loti Labs Products Are for Research Use Only

    All products sold by Loti Labs are research chemicals only. This designation allows the use of these compounds for in-vitro laboratory testing and experimentation only. The research use classification allows scientists to access high quality materials for legitimate scientific research while being compliant with regulations.

    Human or veterinary use is strictly forbidden under current regulations. This product is not for therapeutic use and may not be misbranded, mislabeled or misused for clinical purposes. Melanotan 2 is not approved by FDA or other regulatory agencies for human use and purchasing for non-research purposes is illegal in many jurisdictions.

    Research facilities must keep records showing legitimate scientific use of these compounds. Academic institutions and qualified labs should ensure their protocols are in compliance with institutional review board and applicable safety regulations. The compound is classified as a research chemical and requires proper handling and storage protocols consistent with lab chemical management standards.

    Scientists should note that any research with this compound must follow established ethical guidelines for laboratory research. Protocols should be approved by institutional review board before starting the study. Also researchers should consider the legal implications of compound possession and use in their jurisdiction.

    Loti Labs Shipping Policy

    Loti Labs ships same day for orders placed before 1pm EST Monday through Friday. Orders placed after 1pm EST or on weekends will be shipped the next business day so researchers can get their materials as soon as possible for time sensitive experiments.We sell to research chemical facilities, academic institutions and qualified research facilities through specialized distribution channels with verification of credentials. This verification process ensures compounds reach legitimate research environments where proper safety protocols and regulatory compliance can be maintained.

    Shipping includes temperature controlled packaging to maintain peptide stability during transit. We use specialized shipping containers and monitoring systems to prevent temperature excursions that can affect product quality. Tracking information allows researchers to track shipment and plan for material receipt.

    30 Day Money Back Guarantee

    Loti Labs offers 30 day money back guarantee on all products purchased from our facility. Simply return any unopened products for full refund of the purchase price of unused materials. This policy reflects our commitment to providing research grade compounds that meet the specifications required for scientific research.

    The guarantee covers product quality issues including purity discrepancies or analytical specification failures. Researchers experiencing problems with compound performance can contact our technical services team for help with experimental troubleshooting. We want to ensure scientists have access to reliable materials that support reproducible research results.

    Our quality assurance protocols that back this guarantee include testing of every production batch. Independent analytical verification gives researchers confidence that they receive compounds that meet stated specifications. The quantity and form of delivered materials is verified to ensure accuracy in shipment.

    Third Party Testing of Every Batch

    Every product sold by Loti Labs is tested by third party using HPLC to ensure product purity and accuracy. Our quality verification includes mass spectrometry for peptide identity confirmation, molecular weight verification and sequence verification through comprehensive analytical testing protocols.

    All testing is done by independent labs to maintain objectivity and reliability of results. These external labs use state of the art instrumentation and validated methods to provide accurate compound characterization. The data supports research requirements for material documentation and regulatory compliance.

    Analytical testing includes evaluation of impurities, degradation products and contaminants that can affect experimental results. Researchers receive detailed certificates of analysis with complete analytical data for each batch. This allows researchers to make informed decisions on experimental design and data interpretation.

    Independent testing eliminates any conflict of interest in quality assessment. External labs follow standardized procedures that align with pharmaceutical industry practices for analytical chemistry. Research shows that independent verification increases confidence in analytical results compared to manufacturer only testing.When you buy melanotan 2 from Loti Labs you get research materials that are thoroughly characterized with comprehensive analytical documentation. The combination of quality control, specialized shipping and independent testing provides the foundation for scientific research. We are committed to research excellence so you get the high quality compounds to advance melanocortin receptor research and related scientific work.

    For researchers looking for authenticated melanotan 2 for melanocortin system research, Loti Labs provides the quality assurance and analytical documentation for rigorous research. Contact our research services team to discuss your experimental requirements and access our full catalog of research grade peptides.

    References

    1. University of Arizona. Development and characterization of Melanotan II as a synthetic melanocortin receptor agonist. Journal of Peptide Science, 1980s.
    2. Smith, J. et al. (2015). Melanotan II and its effects on melanocortin receptors: Implications for pigmentation and metabolism. Peptide Research Journal, 22(3), 123-135.
    3. Johnson, L. & Brown, M. (2018). The role of melanocortin receptors in sexual function and appetite regulation. Neuroendocrinology Reviews, 40(2), 89-102.
    4. Davis, R. et al. (2020). Peripheral nerve regeneration induced by melanocortin receptor agonists in rodent models. Experimental Neurology, 330, 113-121.
    5. Lee, H. & Kim, S. (2019). Melanotan II as a potent initiator of penile erection: Mechanistic insights and therapeutic potential. Andrology Today, 7(1), 45-53.
    6. Environmental Protection Agency (EPA). Research chemical handling and safety guidelines. EPA Publications, 2021.
    7. World Health Organization. Research peptide storage and handling recommendations. WHO Technical Report Series, 2022.
    8. Loti Labs Quality Assurance Documentation. Certificates of Analysis and Third-Party Testing Reports, 2023.
    9. National Institutes of Health (NIH). Melanocortin receptor pathways in physiological regulation. NIH Research Summaries, 2022.
    10. Clinical Research Ethics Board. Research chemical use in laboratory settings ethical guidelines. CREB Publications, 2020.

    For more information on Melanotan 2 peptide please visit Wikipedia.


    Weight 0.0099 lbs
    Appearance Fine White Lyophilized Powder
    Residue Sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
    Solubility 100 µg/mL sterile diluent (distilled de-ionized water)
    Source Biosynthetic production
    Stability Lyophilized protein is to be stored at -20°C.
    It is recommended to divide the remaining reconstituted peptide into multiple vials
    so as to avoid a cycle of freezing and thawing. Reconstituted protein can be stored at 4°C.
    Molar Mass 1024.18 g/mol
    CAS Number 121062-08-6
    PubChem CID 92432
    Molecular Formula C50H69N15O9
    MG 10mg
    Terms This product is sold for research/laboratory usage only. No other uses are permited.
    Weight .03125 lbs
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