IGF-1 LR3 1mg

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    IGF-1 LR3 is a potent synthetic version of IGF-1, used by researchers to study muscle growth, development, and repair in animal models. This article examines its design, unique features, and applications in scientific research.

    Key Takeaways

    • IGF-1 LR3 is a synthetic variant of IGF-1 with an extended half-life of 20 to 30 hours, enhancing its stability and usability for research purposes.
    • The compound demonstrates significant anabolic properties, including increased muscle growth, improved recovery, and enhanced protein synthesis, making it valuable for studies on muscle health.
    • IGF-1 LR3 is strictly for laboratory research, not human consumption, and proper storage and handling are crucial to maintaining its effectiveness and integrity.

    Introduction to Insulin Like Growth Factor IGF-1 LR3 by Loti Labs

    IGF-1 LR3, also known as Insulin-like Growth Factor I Long Arg3, is a synthetic version of the natural hormone insulin-like growth factor-1 (IGF-1). This variant has been modified to boost its potency and duration, providing researchers with a powerful tool for studying various biological processes.

    Research suggests that IGF-1 primarily mediates the effects of growth hormone, promoting cell growth and differentiation. It is considered vital for muscle growth, bone development, and tissue repair. The IGF-1 network is intricate, involving IGF-1, IGF-2, insulin, IGF receptors, and IGF binding proteins (IGFBPs).

    Additionally, IGF-1 plays a crucial role in cartilage and bone metabolism, influencing the development and maintenance of these tissues.

    IGF-1 LR3 is regarded as a promising research compound in the field of growth factors. It is marketed as a potent synthetic variant of IGF-1, primarily targeting researchers conducting animal studies. This compound offers a stable and effective tool for investigating growth and differentiation mechanisms.

    The unique selling points of IGF-1 LR3 include its extended half-life, enhanced potency, and improved metabolic effects. These features make it an appealing option for researchers exploring the effects of insulin-like growth factors on various biological systems.

    What is IGF-1 LR3?

    IGF-1 LR3 is a synthetic analog of insulin-like growth factor-1 (IGF-1), a protein that plays a crucial role in cell growth and division. By modifying the amino acid sequence of mature human IGF-1, researchers have created IGF-1 LR3, which boasts an increased half-life and enhanced biological potency. This synthetic variant is designed to bind effectively to both IGF-1 and insulin receptors, thereby promoting protein synthesis and anabolism. The extended half-life of IGF-1 LR3 allows for prolonged biological activity, making it a valuable tool for scientific studies focused on insulin-like growth factors and their impact on various biological processes.

    Role of Insulin-Like Growth Factor in Cell Growth and Division

    Research suggests that insulin-like growth factor (IGF) is pivotal in regulating cell growth and division. IGF-1, in particular, may stimulate cell proliferation and differentiation, which are essential for the growth and development of various tissues. Beyond its role in cell growth, IGF-1 is also thought to play a part in regulating protein metabolism, glucose uptake, and fat metabolism. These functions are crucial for maintaining overall health and well-being. The interaction between IGF-1 and its binding proteins (IGFBPs) is vital for regulating its bioavailability and activity, potentially ensuring that cell growth and division occur in a controlled and coordinated manner. This intricate balance highlights the importance of IGF-1 in promoting insulin-like growth and maintaining cellular health.

    Interaction with the Insulin Receptor

    IGF-1 LR3 interacts with the insulin receptor, a transmembrane receptor that is essential for regulating glucose uptake and protein synthesis. When IGF-1 LR3 binds to the insulin receptor, it activates a signaling pathway that may promote protein synthesis and anabolism, leading to increased muscle growth and repair. This interaction not only enhances protein synthesis but also improves glucose uptake, potentially boosting insulin sensitivity and reducing the risk of insulin resistance. The dual action of IGF-1 LR3 on both IGF-1 and insulin receptors underscores its potential in promoting muscle growth and improving metabolic health.

    Unique Selling Points of IGF-1 LR3

    Research suggests that one of the standout features of IGF-1 LR3 is its significantly extended half-life, which ranges from 20 to 30 hours. This is a substantial improvement over standard IGF-1, which has a much shorter half-life. The prolonged duration allows for more sustained biological activity, making it a valuable tool for extended research studies.

    IGF-1 LR3 comes in a lyophilized powder form, enhancing stability and ease of storage. This form is particularly advantageous for researchers, allowing for convenient handling and precise dosing. The powder can be reconstituted as needed, ensuring stability and effectiveness over time.

    Proper storage conditions for IGF-1 LR3 are recommended at a temperature of -20°C to maintain stability and integrity. This meticulous attention highlights the product’s suitability for rigorous scientific research.

    The unique identifier for IGF-1 LR3 is its CAS Number, 946870-92-4, which ensures the compound’s authenticity and traceability. This level of specificity is crucial for researchers who require precise and reliable compounds for their studies.

    IGF-1 LR3 is strictly for laboratory research and not for human consumption. Its target audience includes researchers focused on animal studies to explore various biological processes and mechanisms. This review will critically examine whether IGF-1 LR3 genuinely offers the benefits touted by the manufacturers.

    Design and Composition of IGF-1 LR3

    Research suggests that IGF-1 LR3’s design and composition are meticulously crafted to ensure maximum efficacy and usability in research settings. Presented in lyophilized powder form, it enhances stability and facilitates precise dosing and handling.

    IGF-1 LR3 is a modified variant of naturally occurring IGF-1, with alterations enhancing its potency and reducing affinity for IGF binding proteins. This modification allows more effective interaction with IGF receptors, promoting more robust biological effects.

    SDS-PAGE analysis of Recombinant Human LR3 IGF-I/IGF-1 reveals a distinct single band at 7 kDa, indicating a high degree of purity and consistency. This purity is crucial for research applications, as it ensures that the compound’s effects can be attributed solely to IGF-1 LR3, without interference from impurities.

    IGF-1 LR3 packaging meets rigorous standards, ensuring stability and effectiveness throughout its shelf life. Proper packaging maintains the integrity of the lyophilized powder, prevents contamination, and facilitates accurate dosing.

    The molecular formula of IGF-1 LR3 is C990H1528N282O300S7, reflecting its complex and precise composition. This advanced design is tailored to enhance its biological activity and stability.

    Overall, research suggests that IGF-1 LR3’s design and composition demonstrate sophistication and attention to detail. These attributes make it a reliable and valuable tool for researchers exploring the effects of insulin-like growth factors in biological systems.

    Effects on Skeletal Muscle Fibers

    Research suggests that IGF-1 LR3 may have a profound impact on skeletal muscle fibers by potentially promoting protein synthesis and anabolism. When IGF-1 LR3 binds to the IGF-1 receptor on muscle cells, it may stimulate the activation of satellite cells, which are crucial for muscle growth and repair. This activation could lead to increased muscle hypertrophy and the development of new muscle fibers. Additionally, IGF-1 LR3 might enhance the expression of genes involved in muscle growth and differentiation, further promoting the development of skeletal muscle. The suggested anabolic effects of IGF-1 LR3 on skeletal muscle fibers make it an attractive subject for research into muscle wasting disorders, highlighting its potential in promoting muscle regeneration and overall muscle health.

    Functional Attributes of IGF-1 LR3 in Promoting Cell Growth

    Research into IGF-1 LR3 highlights several functional attributes useful in scientific studies. A key advantage is its capacity to potentially stimulate muscle growth by activating IGF receptors within muscle cells. This activation may lead to increased protein synthesis and muscle hypertrophy, which is essential for studies on muscle development and repair.

    Another important aspect is the interaction with Mechano Growth Factor (MGF), which research suggests plays a significant role in muscle regeneration and repair by stimulating satellite cell activation and proliferation.

    Compared to regular IGF-1, IGF-1 LR3 has a reduced tendency to bind with IGF binding proteins, potentially resulting in more pronounced metabolic effects and longer activity in the bloodstream, enhancing overall effectiveness.

    Research suggests that IGF-1 LR3 may stimulate cell proliferation and differentiation, contributing to muscle hypertrophy and repair. These effects are valuable in studies on muscle regeneration and recovery, providing insights into underlying mechanisms.

    IGF-1 LR3 is also believed to exhibit anti-apoptotic properties, potentially protecting muscle cells from stress-induced damage. This protection could be crucial during intense physical activity or stress, making IGF-1 LR3 a valuable tool for muscle health research.

    The prolonged half-life of IGF-1 LR3 allows for more sustained anabolic effects compared to regular IGF-1. This extended duration benefits long-term studies requiring consistent biological activity.

    Research suggests IGF-1 LR3 may improve muscle repair and hypertrophy, promote fat metabolism, and inhibit myostatin. These combined effects highlight its potential for research into metabolic processes and muscle health, providing a comprehensive tool for exploring growth factors and cellular functions.

    Real-world Application of IGF-1 LR3 in Animal Studies for Muscle Regeneration

    In real-world applications, researchers using IGF-1 LR3 have observed notable improvements in muscle recovery and performance in animal studies, suggesting its potential for enhancing muscle health and performance in various research models.

    A key benefit noted is the enhanced delivery of nutrients to muscle cells, aiding recovery and performance after workouts. This nutrient delivery is crucial for maintaining muscle health and facilitating recovery, making IGF-1 LR3 valuable for muscle regeneration studies.

    The peptide’s ability to boost promoting protein synthesis and repair muscle tissues more efficiently is another significant advantage. This enhanced repair process is essential for studies on muscle health, providing insights into muscle recovery and regeneration mechanisms.

    However, challenges in applying IGF-1 LR3 include increased sensitivity to pain in subjects. This necessitates careful monitoring of pain thresholds during experiments to ensure subject well-being and result accuracy.

    Proper labeling of vials containing IGF-1 LR3 is necessary to prevent mix-ups and ensure traceability in experiments. This attention to detail is crucial for maintaining research integrity and ensuring reliable, reproducible results.

    Overall, real-world applications of IGF-1 LR3 in animal studies suggest its potential for enhancing muscle recovery and performance. Researchers must remain vigilant about challenges and ensure proper handling and monitoring for accurate, reliable results.

    Observed Effects and Research Outcomes

    Research suggests that IGF-1 LR3 may enhance muscle growth and recovery in various animal models, primarily due to its potential to stimulate protein synthesis and promote anabolic processes in muscle tissues.

    Research highlights IGF-1 LR3’s potential role in reducing post-exercise recovery times in test subjects. This accelerated recovery is crucial for muscle health and performance studies, providing insights into muscle repair and regeneration mechanisms.

    Certain studies suggest a link between IGF-1 LR3 and the promotion of anabolic processes in muscle tissues, possibly leading to improved muscle growth and hypertrophy. These effects are essential for understanding the complex interactions between growth factors and muscle cells.

    IGF-1 LR3’s interaction with muscle cells may lead to improved protein synthesis, as observed in laboratory settings. This synthesis is crucial for maintaining muscle health and facilitating recovery, making IGF-1 LR3 valuable for muscle regeneration research.

    Animal research suggests a potential correlation between IGF-1 LR3 usage and enhanced strength metrics. These findings highlight its potential for improving muscle performance and strength, providing valuable insights for muscle health studies.

    In animal research, combining IGF-1 with NT-3 has shown significant improvements in motor function recovery after spinal cord injuries compared to control groups. This combination has reduced spasticity and improved motor coordination among treated subjects. These findings underscore IGF-1 LR3’s potential for research on nerve recovery and motor function, providing valuable insights into underlying mechanisms.

    Final Thoughts and Recommendations

    In conclusion, research suggests that IGF-1 LR3 offers a potent and reliable tool for researchers exploring the effects of insulin-like growth factors in various biological systems. Its extended half-life, enhanced potency, and improved metabolic effects make it a valuable addition to a researcher’s toolkit.

    However, IGF-1 LR3 is strictly intended for research purposes only. Proper handling and storage are necessary to maintain its stability and effectiveness.

    While alternatives like wild-type IGF-I exist, research indicates that the enhanced potency and extended half-life of IGF-1 LR3 make it a more attractive option for specific research applications. Additionally, its lyophilized powder form enhances usability and stability, providing further advantages.

    Overall, IGF-1 LR3 is considered a valuable and reliable tool for researchers focused on understanding the complex interactions between growth factors and cellular functions. Its unique attributes and observed effectiveness in animal studies suggest it is a worthwhile investment for any research laboratory.

    Summary

    In summary, IGF-1 LR3 stands out as a potent and reliable research compound, offering extended half-life, enhanced potency, and improved metabolic effects. Its design and composition demonstrate a high level of sophistication, tailored to meet the rigorous demands of scientific research.

    The functional attributes of IGF-1 LR3, including its potential to promote muscle growth, enhance protein synthesis, and support muscle recovery, make it a valuable tool for researchers exploring the effects of insulin-like growth factors on various biological systems. The observed effects and research outcomes suggest its potential for enhancing muscle health and performance in animal studies.

    Despite the challenges observed in its application, research suggests that IGF-1 LR3 offers significant benefits for studies on muscle regeneration, metabolic processes, and nerve recovery. Researchers are encouraged to consider IGF-1 LR3 for their studies, ensuring proper handling and storage to maintain its stability and effectiveness.

    Frequently Asked Questions

    What is the half-life of IGF-1 LR3?

    The half-life of IGF-1 LR3 is approximately 20 to 30 hours, which indicates its duration of activity in the body.

    What is the recommended storage condition for the lyophilized protein?

    It is recommended to store lyophilized protein at -20°C for optimal preservation. This will help maintain its stability and effectiveness.

    What is the CAS Number for IGF-1 LR3?

    The CAS Number for IGF-1 LR3 is 946870-92-4.

    What is the molecular formula of IGF-1 LR3?

    The molecular formula of IGF-1 LR3 is C990H1528N282O300S7, which encompasses its complex structure essential for biological function.

    How does IGF-1 LR3 compare in potency to IGF-1?

    Research suggests that IGF-1 LR3 is significantly more potent than IGF-1, with a potency that is three times greater. This enhanced effectiveness makes IGF-1 LR3 a preferred choice for certain applications.

    Citations

    1. Smith, J. & Brown, T. (2021). The Role of Insulin-like Growth Factors in Muscle Regeneration. Journal of Muscle Research, 45(3), 123-135.
    2. Johnson, L. et al. (2022). Mechanisms of IGF-1 LR3 in Promoting Muscle Hypertrophy. Endocrinology and Metabolism Journal, 58(7), 456-467.
    3. Williams, P. & Green, H. (2020). Extended Half-life of IGF-1 LR3: Implications for Research. Growth Factor Reviews, 39(2), 89-101.
    4. Thompson, R. et al. (2023). Interaction of IGF-1 LR3 with Insulin Receptors and its Anabolic Effects. Hormone and Metabolic Research, 55(5), 211-220.
    5. Martinez, A. & Lopez, G. (2019). Stability and Efficacy of Lyophilized IGF-1 LR3 in Laboratory Settings. Journal of Biological Chemistry, 294(22), 845-857.
    6. Patel, K. et al. (2021). IGF-1 LR3 and Muscle Recovery: A Comprehensive Review. Muscle & Nerve, 64(4), 311-324.
    7. Kim, S. & Lee, J. (2020). Comparative Analysis of IGF-1 and IGF-1 LR3 in Animal Models. Journal of Endocrinology, 246(1), 45-56.
    8. Zhang, Y. et al. (2023). IGF-1 LR3 in Muscle Regeneration: Potential Applications and Challenges. Cytokine Growth Factor Reviews, 68(3), 178-192.
    9. Anderson, N. & Clark, D. (2022). The Impact of IGF-1 LR3 on Protein Synthesis and Muscle Hypertrophy. American Journal of Phys.

    BUY IGF-1 LR3 Today from LOTI LABS!

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    For best results in your research, buy IGF-1 LR3 peptides of the highest quality from LOTI LABS.

    Use our products for only research/laboratory purposes. Violation is strictly forbidden. Please read our Terms and Conditions.

    Anyone using products sold by LOTI LABS for any purpose other than research/laboratory use will be added to our no-sell list.

    For more information on IGF-1 LR3 please visit Wikipedia.


    Weight 0.0099 lbs
    Appearance Fine White Lyophilized Powder
    Sequence MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA
    Solubility 100 µg/mL sterile diluent (distilled de-ionized water)
    Source E-coli Expression
    Stability Lyophilized protein is to be stored at -20°C.
    It is recommended to divide the remaining reconstituted peptide into multiple vials
    so as to avoid a cycle of freezing and thawing. Reconstituted protein can be stored at 4°C.
    Molar Mass 9111.0 g/mol
    CAS Number 946870-92-4
    Molecular Formula C990H1528N282O300S7
    MG 1mg
    Terms This product is sold for research/laboratory usage only. No other uses are permited.
    Weight 0.05 lbs
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