DSIP (Delta Sleep Inducing Peptide) 2mg

Buy DSIP Delta Sleep Inducing Peptide at Loti Labs

Delta sleep inducing peptide represents one of the most intriguing neuropeptides in contemporary sleep research. First isolated from cerebral venous blood during slow wave sleep studies in 1977, this naturally occurring substance has become a cornerstone compound for researchers investigating sleep regulation mechanisms and neurobiological pathways. For scientists seeking high-quality research compounds, understanding DSIP’s molecular properties and obtaining verified, pure samples remains essential for reproducible experimental outcomes.

Molecular Structure of DSIP

Delta sleep inducing peptide exhibits a precise molecular architecture that defines its biological activity. Research has established the following technical specifications:

Property	Value
Amino Sequence	Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Molecular Formula	C43H58N10O14
Molecular Weight	850 g/mol
PubChem CID	46506906
CAS Number	62568-57-4

This nonapeptide structure, abbreviated as WAGGDASGE, represents a unique configuration among naturally occurring substance compounds. The specific amino acid sequence contributes to DSIP’s ability to cross biological barriers and interact with central nervous system receptors in research models.

 

Mechanism of Action

DSIP functions as a neuropeptide within experimental systems, demonstrating multiple pathways of biological interaction. Research suggests this sleep inducing peptide operates through modulation of key brain regions, including the hypothalamus and brainstem structures that govern circadian rhythm regulation in animal models.

Studies indicate DSIP influences neurotransmitter systems, particularly gamma-aminobutyric acid (GABA) pathways associated with inhibitory signaling. Unlike conventional compounds that produce pharmacological sedation, research suggests DSIP facilitates natural sleep onset mechanisms without classic sedative effects in experimental subjects.

The compound demonstrates efficient blood-brain barrier penetration in research models, distinguishing it from many other neuropeptides. This property enhances its utility in central nervous system studies and neurobiological research applications. Additionally, research indicates DSIP may interact with opioid receptor systems, contributing to its observed effects in pain perception studies.

Research Studies

Extensive research has examined DSIP’s effects across multiple experimental paradigms, revealing diverse applications in laboratory settings.

Sleep Research Applications

Clinical pilot study data demonstrates DSIP’s effectiveness in improving sleep structure and efficiency in chronic insomniac patients. Research suggests the compound reduces sleep latency and increases sleep duration while helping to normalize disturbed sleep cycles. Studies focusing on severe chronic insomnia have shown that DSIP improves sleep structure without the complications associated with traditional sleep compounds.

Delta wave sleep enhancement represents a particular area of interest, with research indicating DSIP promotes deeper, more restorative sleep phases in experimental subjects. These findings have significant implications for understanding human sleep behavior and developing tools for sleep onset mechanism research.

Pain Management Research

Research has explored DSIP’s applications in chronic pain studies, with findings suggesting reduced pain perception in various experimental models. Clinical studies report promising results for chronic conditions including migraines and chronic tinnitus. Notably, research indicates 97% of patients suffering from alcohol withdrawal showed symptom improvement, while 87% of subjects experiencing opiate withdrawal syndromes demonstrated significant symptom reduction.

These findings suggest DSIP may modulate pain threshold mechanisms and influence withdrawal symptoms through central nervous system pathways. Research continues to investigate the compound’s stress protective potency and its role in managing pronounced pain episodes in laboratory settings.

Neuroprotection Studies

Research indicates DSIP preserves normal mitochondrial function under hypoxic conditions, making it valuable for cerebral ischemia research models. Studies demonstrate the compound’s ability to maintain proper blood flow and reduce oxidative stress in rat brain mitochondria during hypoxia stress conditions.

Additionally, research has shown DSIP’s potential in impaired motor control studies and its effects on various psychiatric illnesses research models. The compound’s neuroprotective properties extend to preserving normal mitochondrial function during oxygen deprivation scenarios.

Cancer Prevention Research

Long-term studies in female mice have demonstrated remarkable findings regarding spontaneous tumor incidence. Research indicates monthly DSIP administration resulted in a 2.6-fold reduction in tumor development and decreased chromosomal defects in bone marrow by 22.6%. These cancer prevention studies suggest potential chemopreventive properties worthy of further investigation.

Additional Research Applications

DSIP research has expanded into multiple therapeutic areas:

• Muscle Physiology: Studies show DSIP inhibits somatostatin in skeletal muscle, potentially promoting hypertrophy and hyperplasia in research models
• Mood Research: The compound modulates monoamine oxidase type A (MAO-A) and serotonin concentrations, opening research avenues for major depressive disorder and major depression studies
• Hormonal Studies: Research indicates DSIP influences growth hormone pathways and helps normalize blood pressure in experimental subjects
• Circadian Research: Studies demonstrate DSIP’s role in regulating circadian rhythm through pineal gland N-acetyltransferase activity

Double blind study protocols have been employed to validate these findings, though researchers note some inconsistencies in replication across different laboratory settings.

Storage and Safety

Proper handling protocols ensure DSIP maintains its integrity throughout research applications. The lyophilized powder should be stored at 4°C or colder, protected from bright light and moisture exposure. While the compound remains stable at room temperature for several weeks, long-term storage requires -20°C conditions for optimal preservation.

Storage Guidelines:

• Lyophilized form: 4°C short-term, -20°C long-term
• Reconstituted solutions: 3+ weeks at +4°C, 3-4 months at -20°C
• Avoid repeated freeze-thaw cycles
• Equilibrate to room temperature before opening sealed vials

Research protocols must emphasize that DSIP represents a research chemical exclusively intended for laboratory applications. The compound requires handling by qualified personnel following appropriate safety data sheet protocols and institutional guidelines.

Benefits of Buying DSIP from Loti Labs

Loti Labs provides clinical-grade DSIP in 2mg lyophilized powder vials, manufactured under stringent quality control protocols. Each batch undergoes comprehensive validation to ensure consistent results across diverse research applications. The company’s commitment to quality makes it an ideal source for scientists conducting sleep research, receptor-ligand binding assays, and advanced neurobiological studies.

Research facilities benefit from Loti Labs’ emphasis on product authenticity and purity verification. The company’s DSIP meets the exacting standards required for reproducible experimental outcomes, supporting researchers investigating everything from sleep apnea mechanisms to stress induced metabolic disturbances.

Key Advantages:

• High-purity compound suitable for diverse research applications
• Consistent batch-to-batch quality for reliable experimental results
• Proper documentation supporting regulatory compliance
• Professional customer support for research inquiries

Products from Loti Labs are for Research Use Only

All compounds sold by Loti Labs carry strict designation as research chemicals exclusively. This classification permits use solely for in-vitro laboratory testing and experimentation within qualified research facilities. Human or veterinary applications are explicitly prohibited under regulatory guidelines.

The sleep inducing peptide DSIP cannot be misbranded, mislabeled, or misused outside legitimate research contexts. Researchers must ensure compliance with institutional review boards and relevant oversight bodies when incorporating DSIP into experimental protocols.

Shipping Policy of Loti Labs

Loti Labs offers same-day shipping for orders placed before 1pm EST Monday through Friday. Orders submitted after 1pm EST or during weekends ship the following business day, ensuring researchers receive their compounds promptly for time-sensitive experiments.

Satisfaction Guarantee

The company provides a 30-day satisfaction guarantee on all research compounds. Researchers may return unopened products for full refund of the purchase price, offering additional assurance for laboratory procurement decisions.

Third Party Testing of Every Batch

Every DSIP batch undergoes rigorous third-party analysis using high-performance liquid chromatography (HPLC) to ensure product purity and accuracy. Mass spectrometry and amino acid analysis verify the correct Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu sequence and confirm 99%+ purity levels.

This comprehensive testing protocol includes:

• HPLC purity assessment
• Mass spectrometry sequence verification
• Amino acid composition analysis
• Contamination screening
• Identity confirmation

Such thorough validation ensures researchers receive authentic DSIP suitable for precise experimental applications, from basic sleep research to complex neurobiological investigations.

References and Citations

1. Monnier M, et al. (1977). Isolation, structure and activity of the delta-sleep-inducing peptide. Proc Natl Acad Sci USA, 74(3): 1282-1286.
2. Schoenenberger GA, et al. (1984). Characterization of a delta-sleep-inducing peptide-like substance from human plasma. Biochem Biophys Res Commun, 122(2): 703-709.
3. Graf MV, Kastin AJ. (1986). Delta-sleep-inducing peptide (DSIP): an update. Peptides, 7(6): 1165-1187.
4. Yehuda S, Carasso RL. (1988). DSIP–a tool for investigating the sleep onset mechanism: a review. Int J Neurosci, 38(3-4): 345-353.
5. Pollard BJ, Pomfrett CJ. (2001). Delta sleep-inducing peptide. Eur J Anaesthesiol, 18(7): 419-422.

The extensive research surrounding delta sleep inducing peptide continues to reveal new applications and mechanisms of action. For researchers seeking to buy DSIP delta sleep inducing peptide, Loti Labs provides the quality assurance and regulatory compliance necessary for advancing scientific understanding of this remarkable compound. Whether investigating sleep architecture, pain management mechanisms, or neuroprotective pathways, high-purity DSIP from verified sources remains essential for meaningful research outcomes.

For more information on Buy DSIP (Delta Sleep Inducing Peptide) 2mg please visit Pubmed.

Weight	.03125 lbs